Phase 4 FL Clinical Trials

128 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 128 trials

Recruiting
Phase 4

A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD) and Hyperinflation

Chronic Obstructive Pulmonary DiseaseHyperinflation
AstraZeneca56 enrolled7 locationsNCT07073950
Recruiting
Phase 4

Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases

Psoriatic Arthritis (PsA)Rheumatoid Arthritis (RA)Systemic Lupus Erythematosus (SLE)+9 more
University of Sao Paulo General Hospital477 enrolled2 locationsNCT07087912
Recruiting
Phase 4

Innovative Steroid Treatment to Reduce Asthma Development in Children After First-time Rhinovirus Induced Wheezing

AsthmaInflammation
St. Olavs Hospital280 enrolled8 locationsNCT03889743
Recruiting
Phase 4

Secukinumab Open Label Roll-over Extension Protocol

Autoimmunity, Inflammation
Novartis Pharmaceuticals1,000 enrolled167 locationsNCT04638647
Recruiting
Phase 4

Colchicine's Effect on Inflammatory Markers

ColchicinePost-operative Atrial FibrillationInflammation in Cardiac Surgery+2 more
Ayesha Ather24 enrolled1 locationNCT07287345
Recruiting
Phase 4

The Bioavailability and Effect on Pouch pH of Esomeprazole After Gastric Bypass

ObesityGastric refluxUlcer, Gastric
Prof Urs Zingg50 enrolled1 locationNCT05320796
Recruiting
Phase 4

The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity

ObesityMenopause Hot Flashes
Mayo Clinic40 enrolled1 locationNCT07218445
Recruiting
Phase 4

Controlled Fluid Removal in Critical Ill Patients With Fluid Overload in the Intensive Care Unit.

Fluid Overload
Morten H. Bestle1,000 enrolled29 locationsNCT04180397
Recruiting
Phase 4

Famotidine and Antacids for Treatment of Dyspepsia

DyspepsiaGERDAcid Reflux
Stony Brook University80 enrolled1 locationNCT06241183
Recruiting
Phase 4

Effect of Misoprostol on Fluid Deficit Volume in Hysteroscopic Myomectomy

Fibroids, UterineFluid DeficitHysteroscopy / Methods
Northwestern University40 enrolled1 locationNCT07286188
Recruiting
Phase 4

Two Dose Levels of Privigen in Pediatric CIDP

Pediatric Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
CSL Behring30 enrolled9 locationsNCT03684018
Recruiting
Phase 4

Evaluation of the Effects of Ketorolac Dose on Duration of Analgesia in Emergency Department (ED) Renal Colic Patients

AnalgesiaEmergenciesRenal Colic+1 more
Hackensack Meridian Health86 enrolled1 locationNCT05776953
Recruiting
Phase 4

The Danish Warfarin-Dialysis Study - Safety and Efficacy of Warfarin in Patients With Atrial Fibrillation on Dialysis

StrokeEnd Stage Renal DiseaseAtrial Fibrillation and Flutter+1 more
Nicholas Carlson718 enrolled13 locationsNCT03862859
Recruiting
Phase 4

Once Daily Intrapleural Enzyme Therapy in Complicated Parapneumonic Effusion or Empyema

EmpyemaPleural EffusionPleural Effusion Associated With Pulmonary Infection+5 more
University of North Carolina, Chapel Hill270 enrolled6 locationsNCT07095361
Recruiting
Phase 4

DICE Study- Diastolic Improvement With Carvedilol & Empagliflozin in Patients With Cirrhosis

Cardiometabolic Risk FactorsCirrhosisCirrhotic Cardiomyopathy+1 more
Post Graduate Institute of Medical Education and Research, Chandigarh400 enrolled1 locationNCT07322237
Recruiting
Phase 4

Sufentanil Infusion vs Intravenous Methadone for Postoperative Analgesia Following Head and Neck Dissection With Free Flap or Rotational Reconstruction

Free Flap Reconstruction
Indiana University128 enrolled1 locationNCT06784999
Recruiting
Phase 4

Woodsmoke Exposure, Influenza Infection, and Nasal Immunity

InfluenzaSmoke Exposure
University of North Carolina, Chapel Hill112 enrolled1 locationNCT06841913
Recruiting
Phase 4

Taper Or Abrupt Steroid Stop: TOASSTtrial

AutoimmuneInflammatory Disorder
University Hospital, Basel, Switzerland530 enrolled16 locationsNCT03153527
Recruiting
Phase 4

Assessment of Metformin for Restoration of Immune Homeostasis in HIV+ and HIV- Individuals With a History of Injection Drug Use

Immune DysregulationHIVSystemic Inflammation+1 more
University of Alabama at Birmingham100 enrolled1 locationNCT06829238
Recruiting
Phase 4

Adenosine Pre-Medication in Primary Percutaneous Coronary Intervention

Acute Myocardial InfarctionST-segment elevation myocardial infarction (STEMI)No-Reflow Phenomenon+1 more
National Institute of Cardiovascular Diseases, Pakistan1,148 enrolled2 locationsNCT07536802