Fuchs Clinical Trials

22 recruitingLast updated: May 21, 2026

There are 22 actively recruiting fuchs clinical trials across 14 countries. Studies span Not Applicable, Phase 1, Phase 3, Phase 2, Phase 4. Top locations include Nijmegen, Gelderland, Netherlands, Portland, Oregon, United States, Boston, Massachusetts, United States. Updated daily from ClinicalTrials.gov.


Fuchs Trials at a Glance

22 actively recruiting trials for fuchs are listed on ClinicalTrialsFinder across 6 cities in 14 countries. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in Nijmegen, Portland, and Boston. Lead sponsors running fuchs studies include Singapore Eye Research Institute, Centre Hospitalier Régional Metz-Thionville, and Aurion Biotech.

Browse fuchs trials by phase

About Fuchs Clinical Trials

Looking for clinical trials for Fuchs? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Fuchs trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Fuchs clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 22 trials

Recruiting
Phase 3

Descemet Endothelial Thickness Comparison Trial II

Fuchs' Endothelial DystrophyFuchs DystrophyFuchs
Stanford University60 enrolled8 locationsNCT05275972
Recruiting
Phase 3

AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction

Corneal EdemaCorneal Endothelial DysfunctionFuchs Endothelial Corneal Dysfunction+1 more
Aurion Biotech120 enrolled12 locationsNCT07368959
Recruiting
Not Applicable

Plasma Rich in Growth Factors in Corneal Endothelial Transplantation

Fuchs' Endothelial DystrophyCorneal Edema
University of Miami100 enrolled2 locationsNCT06261346
Recruiting
Not Applicable

The Belgian Endothelial Surgical Transplant of the Cornea

Pseudophakic Bullous KeratopathyFuchs' Endothelial DystrophyCorneal Edema+2 more
University Hospital, Antwerp220 enrolled11 locationsNCT05436665
Recruiting
Not Applicable

Influence of Supine Positioning on the Outcomes After Descemet Membrane Endothelial Keratoplasty (DMEK)

Descemet Membrane Endothelial Keratoplasty (DMEK)Fuchs' Endothelial Corneal Dystrophy
University Hospital Heidelberg102 enrolled1 locationNCT07373821
Recruiting
Phase 1

PVEK Corneal Implant For Treatment of Corneal Edema

Pseudophakic Bullous KeratopathyFuchs' Endothelial DystrophyCorneal Edema+1 more
Precise Bio15 enrolled3 locationsNCT07325097
Recruiting
Phase 2

DT-168 in Keratoplasty Patients With Fuchs Endothelial Corneal Dystrophy

Fuchs' Endothelial Corneal DystrophyFuchs
Design Therapeutics, Inc.28 enrolled2 locationsNCT07024693
Recruiting
Phase 1

Study to Assess Safety and Tolerability of Multiple Doses of EO2002

Endothelial DysfunctionPseudophakic Bullous KeratopathyFuchs' Endothelial Dystrophy+5 more
Asociación para Evitar la Ceguera en México12 enrolled1 locationNCT05636579
Recruiting

SUCCESS Score Validation in Fuchs Dystrophy

Fuchs' Endothelial Corneal Dystrophy
Instituto Ramón y Cajal de Investigación Sanitaria250 enrolled1 locationNCT07265388
Recruiting

A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal Ectasia

KeratoconusFuchs' Endothelial DystrophyEctasia+1 more
Massachusetts General Hospital168 enrolled1 locationNCT02118922
Recruiting
Phase 4

The OPTIMISE Study

Intraocular PressurePseudophakic Bullous KeratopathyFuchs' Endothelial Dystrophy
Maastricht University Medical Center342 enrolled8 locationsNCT05716945
Recruiting
Phase 2

Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy

Fuchs' Endothelial Corneal Dystrophy
Massachusetts Eye and Ear Infirmary45 enrolled1 locationNCT04440280
Recruiting
Phase 1

Safety and Efficacy of Tissue Engineered Endothelial Keratoplasty

Fuchs' Endothelial DystrophyBullous KeratopathyMild to Moderate Corneal Endothelial Decompensation+1 more
Singapore Eye Research Institute30 enrolled1 locationNCT04319848
Recruiting

OCT in Fuchs' Dystrophy

Pseudophakic Bullous KeratopathyFuchs Dystrophy
Oregon Health and Science University60 enrolled1 locationNCT04258787
Recruiting

DISCOVER Study: Microscope-integrated Intraoperative OCT Study

Retinal diseasesEpiretinal MembraneRetinal Detachment+2 more
The Cleveland Clinic3,000 enrolled1 locationNCT02423213
Recruiting

Comparison of Outcomes Between Femtosecond Laser-Assisted and Conventional Phacoemulsification in Fuchs Endothelial Corneal Dystrophy Patients With Cataracts

CataractFuchs' Endothelial Corneal Dystrophy
Eye & ENT Hospital of Fudan University120 enrolled1 locationNCT06966167
Recruiting

FECD-TRACE: Fuchs' Endothelial Corneal Dystrophy TRAjectory and Correlation With Genotype in the United Kingdom

Corneal DystrophyFuchs' Endothelial DystrophyFuchs Dystrophy+2 more
University College, London500 enrolled1 locationNCT06881771
Recruiting

Prognosis of Posterior Lamellar Keratoplasty, an Observational Cohort Study

Pseudophakic Bullous KeratopathyFuchs' Endothelial Corneal Dystrophy
Centre Hospitalier Régional Metz-Thionville1,000 enrolled1 locationNCT06859411
Recruiting
Not Applicable

Trial Comparing Cataract Surgery With Triple-DMEK in Patients With Cataract and Fuchs Endothelial Corneal Dystrophy

Cataract SurgeryCataract and Fuchs Endothelial Corneal Dystrophy
University of Cologne120 enrolled4 locationsNCT06425666
Recruiting
Phase 3

The Effects of Ripasudil in Patients With FED Undergoing Femtosecond Laser Assisted Cataract Surgery

CataractFuchs' Endothelial Dystrophy
Singapore Eye Research Institute120 enrolled1 locationNCT06048380