Phase 4 Function Clinical Trials

86 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 86 trials

Recruiting
Phase 4

Postpartum Vaginal Estrogen for Breastfeeding Patients

BreastfeedingVaginal AtrophyPostpartum Sexual Dysfunction
University Hospitals Cleveland Medical Center100 enrolled1 locationNCT05457972
Recruiting
Phase 4

SGLT2i Therapy in Islet Transplantation (SIT)

DiabetesPartial Islet FunctionTPIAT
University of Minnesota40 enrolled1 locationNCT07228195
Recruiting
Phase 4

A Study to Investigate of the Effects of Opioid Exposure on the Ability of the Diaphragm Muscle

Respiratory Function LossRespiratory Complication
Mayo Clinic69 enrolled1 locationNCT05856136
Recruiting
Phase 4

PRP vs PRP+Betamethasone vs Betamethasone Injection for Upper Trapezius Myofascial Pain

Trigger Point in Trapezius MuscleMyofascial Pain Dysfunction SyndromeTrigger Points, Myofascial
University of Kyrenia150 enrolled2 locationsNCT07547605
Recruiting
Phase 4

L-Citrulline and Tadalafil for Mild to Moderate Erectile Dysfunction

Erectile Dysfunction
Beni-Suef University133 enrolled1 locationNCT07642505
Recruiting
Phase 4

Efficacy of Vevye Ophthalmic Solution for the Treatment of Meibomian Gland Dysfunction

Meibomian Gland Dysfunction (MGD)
University of Alabama at Birmingham48 enrolled1 locationNCT07224529
Recruiting
Phase 4

Cervicothoracic Sympathetic Block Evaluation for Post COVID Condition

Autonomic Dysfunction
University Health Network, Toronto78 enrolled3 locationsNCT07468604
Recruiting
Phase 4

Ocular Surface Health and Tear Film Stability With a Nasal Spray Dry Eye Treatment

Dry EyeMeibomian gland dysfunction
University of California, Berkeley65 enrolled1 locationNCT07606625
Recruiting
Phase 4

Evaluation of Efficacy of Skål Pro Powder on Symptoms of Irritable Bowel Syndrome

Pathologic ProcessesIntestinal DiseaseGastrointestinal Diseases+5 more
EP Plus Group Sdn Bhd60 enrolled1 locationNCT06271538
Recruiting
Phase 4

The Research of Integrated Traditional Chinese and Western Medicine on Hypothalamic Amenorrhea

Functional Hypothalamic Amenorrhea
Peking Union Medical College Hospital210 enrolled1 locationNCT07580950
Recruiting
Phase 4

LANdiolol to Avoid TAchycardia in Patients at Risk for Cardiovascular Events Undergoing Major Non-cardiac Surgery

myocardial injury after non-cardiac surgeryAutonomic DysfunctionCardiovascular (CV) Risk+3 more
Insel Gruppe AG, University Hospital Bern114 enrolled1 locationNCT07168421
Recruiting
Phase 4

Safety and Efficacy of Collagenase Clostridium Histolyticum After Prior Intralesional PRP for Peyronie's Disease

Genital Diseases, MaleSexual Dysfunctions, PsychologicalPeyronie Disease
University of Miami22 enrolled2 locationsNCT05777031
Recruiting
Phase 4

Dual Orexin Antagonism and Emotion and Affective Processing Study

Cognitive functioningLearningEmotional Processing
University of Oxford62 enrolled1 locationNCT07267559
Recruiting
Phase 4

Atorvastatin Pretreatment in Cerebrovascular Events (APICES) After Flow Diverter Implantation

Endothelial DysfunctionIschemic StrokeCerebrovascular Event+4 more
Duan Chuanzhi354 enrolled1 locationNCT06308952
Recruiting
Phase 4

Daily Tadalafil 5 mg Combined With On-Demand Sildenafil 100 mg for Treatment of Erectile Dysfunction in PDE-5I Non Responder Patients

Erectile Dysfunctions
Mansoura University500 enrolled11 locationsNCT07391579
Recruiting
Phase 4

Effect of a GnRH Analog on Hepatic Steatosis

EndometriosisMetabolic Dysfunction-Associated Steatotic Liver DiseaseNonalcoholic Fatty Liver
Aristotle University Of Thessaloniki62 enrolled2 locationsNCT06523530
Recruiting
Phase 4

Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years

Cognitive FunctionMotor FunctionContrast Media
Guerbet2,076 enrolled51 locationsNCT04373564
Recruiting
Phase 4

Evaluation of Suvorexant for Reduction of Brain Reactivity in Patients With Cannabis Use Disorder (Pilot Study)

Cannabis Use DisorderCue-reactivityFunctional MRI+1 more
Massachusetts General Hospital20 enrolled1 locationNCT06584942
Recruiting
Phase 4

Efficacy of Clostridium Butyricum in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia

DepressionAnxietyFunctional Dyspepsia+1 more
Xijing Hospital of Digestive Diseases180 enrolled1 locationNCT07182890
Recruiting
Phase 4

Efficacy of Bacillus Coagulans in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia

DepressionAnxietyFunctional Dyspepsia+1 more
Xijing Hospital of Digestive Diseases180 enrolled1 locationNCT07187492