Early Phase 1 GAN Clinical Trials

12 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 112 of 12 trials

Recruiting
Early Phase 1

CD19/BCMA UCAR-T for B Cell-Related Autoimmune Disease

IgA Nephropathy (IgAN)Autoimmune DiseasesSystemic Sclerosis (SSc)+3 more
The Children's Hospital of Zhejiang University School of Medicine15 enrolled1 locationNCT07586267
Recruiting
Early Phase 1

Donor Virus-Specific CMV or AdV CTL to Treat CMV or AdV Reactivation or Disease After Solid Organ or HCT

Allogeneic Hematopoietic Stem Cell Transplantation RecipientAdenovirusCytomegalovirus+2 more
Sumithira Vasu20 enrolled2 locationsNCT03665675
Recruiting
Early Phase 1

Allogeneic CD19/BCMA CAR-T for B Cell-Related Autoimmune Disease

IgA Nephropathy (IgAN)Autoimmune DiseasesSystemic Sclerosis (SSc)+3 more
The Children's Hospital of Zhejiang University School of Medicine15 enrolled1 locationNCT07507201
Recruiting
Early Phase 1

iMagemHTT-009- FIH Evaluation of Novel Mutant Huntingtin PET Radioligand [11C]CHDI-00491009

Huntington’s DiseaseHuntington DiseasePositron Emission Tomography+6 more
CHDI Foundation, Inc.27 enrolled1 locationNCT06634628
Recruiting
Early Phase 1

In Vivo PARP-1 Expression With 18F-FluorThanatrace PET/CT in Patients With Pheochromocytoma and Paraganglioma

ParagangliomaPheochromocytoma
Heather Wachtel30 enrolled1 locationNCT05636540
Recruiting
Early Phase 1

B-GLUCANCER2 : A Pilot Study Evaluating a New Method for Cancer Detection by Measuring the Activity of Different Glycosidase Enzymes in the Plasma of Patients With a Localized Cancer.

Breast CancerPancreatic CancerPulmonary Cancer+4 more
Poitiers University Hospital220 enrolled1 locationNCT07236177
Recruiting
Early Phase 1

A Clinical Study Evaluating the Safety and Efficacy of GT719 Universal Cell Injection in the Treatment of Immune-mediated Kidney Diseases

IgA Nephropathy (IgAN)Membranous NephropathyANCA-associated Vasculitis (AAV)/ANCA-associated Glomerulonephritis (AAGN)+2 more
Grit Biotechnology30 enrolled1 locationNCT07389499
Recruiting
Early Phase 1

Anti-CD19/BCMA CAR-NK Cells in Patients With B Cell Mediated Autoimmune Disease

Autoimmune DiseasesSystemic Lupus ErthematosusMulti-Drug Resistant Nephrotic Syndrome+1 more
The Children's Hospital of Zhejiang University School of Medicine36 enrolled1 locationNCT06792799
Recruiting
Early Phase 1

Safety and Efficacy of ONT01 in Lupus

Systemic Lupus ErythematosusSLELupus Nephritis (LN)+5 more
Hospital for Special Surgery, New York61 enrolled1 locationNCT07107659
Recruiting
Early Phase 1

Pulsed RF Neuromodulation and Leukocyte-Rich PRP for Refractory Low Back Pain

Multi-Organ Disorder
Iffat Anwar Medical Complex100 enrolled1 locationNCT06524531
Recruiting
Early Phase 1

18F-MFBG PET/CT in the Evaluation of Neural Crest Tumor

ParagangliomaPheochromocytomaNeuroblastoma+1 more
Peking Union Medical College Hospital150 enrolled1 locationNCT05069220
Recruiting
Early Phase 1

Clinical Study of High Concentration Ganciclovir Eye Drops in the Treatment of Cytomegalovirus Retinitis

Cytomegalovirus RetinitisGanciclovir Eye Drops
Tianjin Medical University15 enrolled1 locationNCT05911503