Phase 2 GIST Clinical Trials
12 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–12 of 12 trials
Recruiting
Phase 1Phase 2
A Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced Malignancies
GIST
Deciphera Pharmaceuticals, LLC94 enrolled25 locationsNCT05957367
Recruiting
Phase 2
Comparing Regorafenib Combined With Envafolimab to Physician's Choice in Patients With Metastatic Gastrointestinal Stromal Tumors Harboring KIT Exon 17 Mutations Refractory to Standard Treatment
GIST - Gastrointestinal Stromal TumorKIT Gene Mutation
Jian Li100 enrolled1 locationNCT07559864
Recruiting
Phase 2
A Prospective, Randomized, Multicenter, Comparative Study of the Efficacy of Imatinib Resumption Combined With Atezolizumab Versus Imatinib Resumption Alone in Patients With Unresectable Advanced Gastrointestinal Stromal Tumors (GIST) After Failure of Standard Treatments
Unresectable Gastrointestinal Stromal Tumor (GIST)Locally Advanced Gastrointestinal Stromal Tumor (GIST)Metastatic Gastrointestinal Stromal Tumor
Centre Leon Berard110 enrolled13 locationsNCT05152472
Recruiting
Phase 2
KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting
GISTGIST - Gastrointestinal Stromal TumorGastrointestinal Tumors+2 more
Kumquat Biosciences Inc.46 enrolled1 locationNCT07406633
Recruiting
Phase 1Phase 2
Lenvatinib After Progression on Imatinib, Sunitinib, and Regorafenib for GIST Patients
GIST
Asan Medical Center48 enrolled1 locationNCT07096609
Recruiting
Phase 1Phase 2
A Master Protocol to Evaluate DCC-3009 in Gastrointestinal Stromal Tumor (GIST)
Gastrointestinal Stromal Tumor (GIST)
Deciphera Pharmaceuticals, LLC120 enrolled10 locationsNCT06630234
Recruiting
Phase 2
Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue Sarcoma
Soft Tissue Sarcoma AdultLeiomyosarcomaSynovial Sarcomas+6 more
Oslo University Hospital110 enrolled4 locationsNCT07169344
Recruiting
Phase 2
Efficiency of Imatinib Treatment After 10 Years of Treatment in Patients With Gastrointestinal Stromal Tumours (GIST) (Gist-Ten)
C-KIT MutationMetastatic Gastrointestinal Stromal Tumor (GIST)Advanced Gastrointestinal Stromal Tumor (GIST)
Centre Leon Berard50 enrolled13 locationsNCT05009927
Completed
Phase 2
A randomised phase II trial of imatinib alternating with regorafenib compared to imatinib alone for the first line treatment of advanced gastrointestinal stromal tumour (GIST)
Metastatic gastrointestinal stromal tumour (GIST)
Australasian Gastro-Intestinal Trials Group (AGITG)76 enrolled20 locationsACTRN12614000950662
Completed
Phase 2
Effect of ion channel modification on symptoms in chronic eczema
Dermatologist or allergist diagnosed eczema
Peter Smith20 enrolled1 locationACTRN12612000249853
Completed
Phase 2
The REGISTER Study: A multicentre phase II study of risk evaluation in gastrointestinal stromal tumours (GIST) with selective therapy escalation for response
Gastrointestinal Stromal Tumour (GIST)
AGITG80 enrolled14 locationsACTRN12608000392369
Completed
Phase 2Phase 3
Providing parents in a neonatal intensive care unit with audiorecordings of their conversation with neonatologists: a randomised trial.
2) Maternal depression, anxiety, general health and parenting stress scales.1) Poor recall by mothers of information given by neonatologists.
Dr Andrew Johnson, The Townsville Hospital200 enrolled1 locationACTRN12606000478516