Phase 3 HAE Clinical Trials
60 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 60 trials
Recruiting
Phase 3
The Fifth INTEnsive pReventing Secondary Injury in Acute Cerebral Haemorrhage Trial Within ACT-GLOBAL
Acute intracerebral haemorrhageAcute StrokeIntracerebral Hemorrhage+2 more
The George Institute2,000 enrolled2 locationsNCT06763055
Recruiting
Phase 3
Efficacy and Safety of Minocycline in Patients With Acute Ischaemic Stroke Receiving Intravenous Thrombolysis
Ischaemic Stroke
Beijing Tiantan Hospital934 enrolled3 locationsNCT07526987
Recruiting
Phase 2Phase 3
DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol
Haematological MalignancySolid Tumour
Cancer Research UK825 enrolled27 locationsNCT05722886
Recruiting
Phase 3
A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A
Haemophilia AHaemophilia A With Inhibitors
Novo Nordisk A/S451 enrolled152 locationsNCT05685238
Recruiting
Phase 3
Study to Provide Continued Access to Treatment for Patients Completing a Previous Trial With Efanesoctocog Alfa
Haemophilia A (Moderate or Severe)
Swedish Orphan Biovitrum104 enrolled21 locationsNCT06716814
Recruiting
Phase 3
A Phase III Clinical Study to Evaluate the Efficacy, Safety, and Tolerability of Plonmarlimab in Subjects With Relapsed/Refractory Rheumatic and Immunologic Disease-associated Haemophagocytic Lymphohistiocytosis (Also Known as Macrophage Activation Syndrome [MAS])
Relapsed/Refractory Rheumatic and Immunologic Disease-associated Haemophagocytic Lymphohistiocytosis
TJ Biopharma Co., Ltd.30 enrolled15 locationsNCT07208058
Recruiting
Phase 3
Timing to Restart Direct Oral Anticoagulants After Traumatic Intracranial Haemorrhage
Traumatic Intracranial Haemorrhage
Walton Centre NHS Foundation Trust1,084 enrolled2 locationsNCT06322953
Recruiting
Phase 3
Phase 3 Extension Study of ADX-324 in Participants With Hereditary Angioedema (HAE)
Hereditary Angioedema (HAE)Hereditary Angioedema - Type 1Hereditary Angioedema - Type 2+1 more
ADARx Pharmaceuticals, Inc.90 enrolled48 locationsNCT07428499
Recruiting
Phase 3
STOP-HAE: A Phase 3 Study of ADX-324 in HAE
Hereditary AngioedemaHereditary Angioedema - Type 1Hereditary Angioedema - Type 2+1 more
ADARx Pharmaceuticals, Inc.90 enrolled51 locationsNCT06960213
Recruiting
Phase 3
A Study to Investigate the Efficacy, Safety, and Pharmacokinetics of Oral Rilzabrutinib Compared With Placebo in Participants 18 Years of Age and Older With Warm Autoimmune Hemolytic Anemia
Autoimmune Haemolytic Anaemia
Sanofi90 enrolled95 locationsNCT07086976
Recruiting
Phase 3
Donidalorsen Treatment in Children With Hereditary Angioedema
Hereditary Angioedema (HAE)
Ionis Pharmaceuticals, Inc.20 enrolled10 locationsNCT07298447
Recruiting
Phase 3
Long-Term, Open-label Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE
Hereditary Angioedema (HAE)
Pharvaris Netherlands B.V.170 enrolled62 locationsNCT06679881
Recruiting
Phase 3
A Study of Navenibart in Participants With Hereditary Angioedema
Hereditary Angioedema (HAE)
Astria Therapeutics, Inc.145 enrolled87 locationsNCT06842823
Recruiting
Phase 3
Avoiding Anticoagulation After IntraCerebral Haemorrhage
Atrial FibrillationIntracerebral HemorrhageMicrohaemorrhage
University Hospital, Lille300 enrolled3 locationsNCT03243175
Recruiting
Phase 3
EVE TRIAL , ALMA SYSTAM
Postpartum Haemorrhage (PPH)PPHPostpartum Hemorrhage (Primary)
ResQ Medical Ltd50 enrolled2 locationsNCT06646653
Recruiting
Phase 3
Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia Gravis
Myasthaenia Gravis
Cartesian Therapeutics100 enrolled34 locationsNCT06799247
Recruiting
Phase 2Phase 3
Minocycline in Stroke Study at Maimonides
Cerebrovascular Accident (Stroke)StrokeMortality+4 more
Joyce Chen1,164 enrolled1 locationNCT07237048
Recruiting
Phase 3
Efficacy and Safety Evaluation Study of SCT800 in Previously Untreated Hemophilia A Patients.
Haemophilia A
Sinocelltech Ltd.36 enrolled1 locationNCT07437404
Recruiting
Phase 3
Fibrinogen Early In Severe Trauma StudY II
coagulopathyTraumaHaemorrhagic Shock
Australian and New Zealand Intensive Care Research Centre900 enrolled24 locationsNCT05449834
Recruiting
Phase 2Phase 3
DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With HER2 Amplification or Activating Mutations
Ovarian NeoplasmsColorectal NeoplasmsUrinary Bladder Neoplasm+8 more
Cancer Research UK30 enrolled27 locationsNCT05786716