Phase 3 HCC Clinical Trials

10 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 110 of 10 trials

Recruiting
Phase 3

DEB-TACE vs cTACE in HCC After TIPS

Hepatocellular Carcinoma (HCC)TACETIPS+2 more
First Affiliated Hospital, Sun Yat-Sen University206 enrolled1 locationNCT07322848
Recruiting
Phase 2Phase 3

A Study to Evaluate the Efficacy and Safety of IBI310 and Sintilimab Combination Therapy in Patients With Hepatocellular Carcinoma as First-line Treatment.

Hepatocellular Carcinoma (HCC)
Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD.680 enrolled2 locationsNCT07490262
Recruiting
Phase 2Phase 3

Comparison of SBRT and SIRT With Combination IO for Locally-advanced, Unresectable HCCs (BIIRTH)

Hepatocellular Carcinoma (HCC)
Tuen Mun Hospital106 enrolled1 locationNCT07293468
Recruiting
Phase 2Phase 3

Transarterial Chemoembolization (TACE) Plus ABCB1 Inhibition Versus TACE Alone in Patients With Hepatocellular Carcinoma

Hepato Cellular Carcinoma (HCC)
University Hospital, Basel, Switzerland152 enrolled3 locationsNCT07302919
Recruiting
Phase 2Phase 3

The Efficacy of Sequential Treatment With Bevacizumab Combined With Atezolizumab in Advanced Liver Cancer With MASLD

HCC - Hepatocellular Carcinoma
Eastern Hepatobiliary Surgery Hospital20 enrolled1 locationNCT07285850
Recruiting
Phase 3

Camrelizumab and Apatinib With or Without FOLFOX Chemotherapy for Advanced HCC

Chemotherapy EffectHepato Cellular Carcinoma (HCC)
Linhui Peng326 enrolled1 locationNCT07267806
Recruiting
Phase 2Phase 3

Single-arm Clinical Trial of TACE in Combination With Icaritin as Adjuvant Therapy After Surgery in Patients With Hepatocellular Carcinoma at High Risk of Recurrence

Hepatocellular Carcinoma (HCC)
Zhujiang Hospital30 enrolled1 locationNCT06644937
Recruiting
Phase 3

Adjuvant Radiotherapy of Sintilimab Versus TACE for HCC

Radiotherapy, AdjuvantHepatocellular Carcinoma (HCC)Immune Checkpoint Inhibitor+2 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences286 enrolled1 locationNCT07186621
Recruiting
Phase 3

Continuation of First-line Therapy With Radiotherapy Versus Early Switch to Second-line Therapy in Oligoprogressive HCC

RadiotherapyOligoProgressive Metastatic DiseaseHepatocellular Carcinoma (HCC)+1 more
Shandong Cancer Hospital and Institute132 enrolled1 locationNCT06841172
Recruiting
Phase 2Phase 3

A Phase II/III Trial Comparing Transarterial Tirapazamine Embolization (TATE) With cTACE for Intermediate-stage Liver Cancer.

HCC
Zhejiang Raygene Pharmaceuticals Co., Ltd300 enrolled2 locationsNCT06844357