Phase 3 Headache Clinical Trials
8 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–8 of 8 trials
Recruiting
Phase 3
Multi-center RCT of IV Ketamine Efficacy and Safety in Chronic Daily Headaches
Chronic Daily Headache
University Health Network, Toronto56 enrolled2 locationsNCT05306899
Recruiting
Phase 2Phase 3
Transnasal Sphenopalatine Ganglion Block for Treatment of Acute Subarachnoid Hemorrhage Associated Headache
SAH (Subarachnoid Hemorrhage)Headache
University of California, Davis40 enrolled1 locationNCT06621329
Recruiting
Phase 3
Repeated GON Injections in CCH
Cluster Headache
Leiden University Medical Center50 enrolled2 locationsNCT05324748
Recruiting
Phase 3
Idebenone for the Preventive Treatment of Migraine
Migraine DisordersHeadache Disorders
Second Affiliated Hospital, School of Medicine, Zhejiang University180 enrolled1 locationNCT04151472
Recruiting
Phase 3
Safety and Efficacy of Botulinum Toxin A in Patients With Posttraumatic Headache
Posttraumatic Headache
Danish Headache Center80 enrolled1 locationNCT06839118
Recruiting
Phase 3
Botulinum Toxin Type A Blockade of the Sphenopalatine Ganglion in Treatment-refractory Chronic Cluster Headache
Cluster Headache
Norwegian University of Science and Technology112 enrolled5 locationsNCT03944876
Completed
Phase 3Phase 4
A double-blind randomised controlled study to evaluate the effectiveness of orally-dosed Palmitoylethanolamide (PEA) compared to ibuprofen for reducing pain severity and duration of headaches in healthy participants aged 18 years and older.
Headache
RDC Global Pty Ltd80 enrolled1 locationACTRN12618000294257
Not Yet Recruiting
Phase 3
Inadvertant dural puncture in labour: Intrathecal Catheter versus Epidural (The ICE Pilot Study)
Epidural blood patchPostdural puncture headache
Allan M Cyna12 enrolled1 locationACTRN12608000009314