Phase 1 Healt Clinical Trials
583 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 583 trials
Recruiting
Phase 1
A Study to Test How Well Different Doses of BI 3034701 Are Tolerated by Japanese Healthy People and Japanese People With Obesity or Overweight
ObesityHealthy
Boehringer Ingelheim48 enrolled3 locationsNCT07693231
Recruiting
Phase 1
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)
HealthyMild Cognitive ImpairmentAlzheimer s Disease
National Institute of Mental Health (NIMH)90 enrolled1 locationNCT07169630
Recruiting
Phase 1
A Phase 1, First-in-Human Study of CND319 in Healthy Participants and Patients With Rheumatic Diseases
Rheumatoid ArthritisSjogren's SyndromeHealthy Participants Study
Candid Therapeutics105 enrolled1 locationNCT07712939
Recruiting
Phase 1
Safety, Tolerability and Pharmacokinetics Study of L608 in Healthy Adults
healthy adult participants
Pharmosa Biopharm Inc.40 enrolled1 locationNCT06429930
Recruiting
Phase 1
FIH Study to Evaluate the Tolerability of PF-07832837 in Healthy Adults and Patients
Healthy ParticipantsAtopic Dermatitis
Pfizer119 enrolled5 locationsNCT06564389
Recruiting
Phase 1Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Healthy Volunteers, Pulmonary Arterial Hypertension
Novartis Pharmaceuticals232 enrolled87 locationsNCT06649110
Recruiting
Phase 1
A Study to Investigate the Effect of AZD6234, AZD9550, and a Combination of AZD9550 and AZD6234 on Pharmacokinetics of Combined Oral Contraceptive Ethinyl Estradiol/Levonorgestrel in Healthy Female Participants Living With Overweight or Obesity
Healthy Participants
AstraZeneca50 enrolled2 locationsNCT07013643
Recruiting
Phase 1
A Study of BL1332 on Capsaicin-Induced Ocular Pain in Healthy Trial Participants
Healthy
Bausch & Lomb Incorporated28 enrolled1 locationNCT07717918
Recruiting
Phase 1
A Study of LY4065967 in Healthy Participants
Healthy
Eli Lilly and Company36 enrolled2 locationsNCT07607483
Recruiting
Phase 1
Study of XmAb412 in Healthy Participants
Not Applicable - Healthy Adult Participants
Xencor, Inc.128 enrolled2 locationsNCT07713485
Recruiting
Phase 1
PET Imaging of Noradrenergic Transmission in the Brain
Healthy
National Institute of Mental Health (NIMH)40 enrolled1 locationNCT07686393
Recruiting
Phase 1
A Research Study of a New Medicine, NNC9733-0001, in Healthy Participants and Participants With Type 2 Diabetes
Healthy VolunteerType 2 Diabetes
Novo Nordisk A/S60 enrolled1 locationNCT07270731
Recruiting
Phase 1
A Study of LY4298445 in Healthy Participants and Participants With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA)
Rheumatoid ArthritisHealthySystemic Lupus Erythematosus
Eli Lilly and Company63 enrolled9 locationsNCT07276958
Recruiting
Phase 1
Phase 1 Challenge Study Using rDEN2delta30-7169 to Evaluate Host-Pathogen Interactions in Primary, Homotypic, and Heterotypic Dengue Virus Infection
Healthy VolunteersDengueHuman Challenge Trial
National Institute of Allergy and Infectious Diseases (NIAID)200 enrolled1 locationNCT07706686
Recruiting
Phase 1
Study Evaluating Safety & Tolerability of Migaldendranib in Healthy Volunteers
Healthy Volunteers
Ashvattha Therapeutics, Inc.36 enrolled1 locationNCT07370155
Recruiting
Phase 1
Safety of RAD301 in Healthy Human Volunteers and Patients With Pancreatic Cancer or Other Solid Tumors
Non-small Cell Lung Cancer (NSCLC)Ovarian CancerCervical Cancer+4 more
Radiopharm Theranostics, Ltd9 enrolled2 locationsNCT05799274
Recruiting
Phase 1
Developing Biomarkers of Dietary Intake: Dose Dependent Measurement of Sugar Intake
Healthy VolunteersDiet Therapy
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)60 enrolled1 locationNCT04799301
Recruiting
Phase 1
Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Buprenorphine/Naloxone or Methadone
Healthy Volunteer Study
Atea Pharmaceuticals, Inc.32 enrolled3 locationsNCT07314346
Recruiting
Phase 1
A Study of B-3E07 and Forsteo® in Healthy Adult Female Participants
Healthy Volunteers
Syneos Health48 enrolled1 locationNCT07497503
Recruiting
Phase 1
A Study of Food Effect on Tersolisib (LY4064809) in Healthy Participants
Healthy
Eli Lilly and Company60 enrolled2 locationsNCT07662798