Phase 4 Health Clinical Trials

66 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 66 trials

Recruiting
Phase 4

Longitudinal Tracking of Bone Marrow Plasma Cell Responses to Licensed Human Vaccines

Healthy AdultsImmunology
Washington University School of Medicine25 enrolled1 locationNCT07493460
Recruiting
Phase 4

Concurrent Versus Sequential Administration of Tdap and RSV Vaccines in Pregnancy

PregnancyHealthyRSV+1 more
Canadian Immunization Research Network60 enrolled4 locationsNCT07097012
Recruiting
Phase 4

Effects of Donor-recipient Sex-matched Blood Transfusion on Patient Outcomes

CardiovascularRed Blood Cell TransfusionsSex Differences+3 more
Michelle Zeller11,082 enrolled8 locationsNCT06840756
Recruiting
Phase 4

Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body Dementia

Dementia With Lewy BodiesParkinson Disease DementiaHealthy (Controls)
Virginia Commonwealth University120 enrolled1 locationNCT07284290
Recruiting
Phase 4

Effects of GH and Lirglutide on AgRP

HealthyGrowth Hormone Deficiency
Columbia University40 enrolled1 locationNCT05681299
Recruiting
Phase 4

Observing Metabolism of EPA With Consideration of Genetics And Sex

HealthyOmega 3Metabolism, Lipids
University of Toronto64 enrolled1 locationNCT06975241
Recruiting
Phase 4

KarXT Concentrations in the Breast Milk and Plasma of Lactating Females

Healthy Volunteers
Karuna Therapeutics, Inc., a Bristol Myers Squibb company8 enrolled1 locationNCT07257120
Recruiting
Phase 4

Pasteurised Donor Human Milk Supplementation for Term Babies

neonatal intensive care unitMental Health IssueHospital Length of Stay+4 more
The University of Queensland1,444 enrolled4 locationsNCT06993103
Recruiting
Phase 4

Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics

Low birthweightPregnancyPreterm Birth+6 more
Duke University2,500 enrolled2 locationsNCT05757167
Recruiting
Phase 4

Comparing Dynamic Navigation to Static Navigation in the Implant Placement

Healthy AdultsDental ImplantAccuracy
Ain Shams University20 enrolled1 locationNCT07291336
Recruiting
Phase 4

Investigation of Locus Coeruleus Function in Sustained Attention

Attention - no Condition is Being Assessed - Healthy Adults
University of California, Davis40 enrolled1 locationNCT06041048
Recruiting
Phase 4

Effects of Energy Drinks on Cardiovascular Endpoints

Healthy VolunteersSafety After Oral Intake
University of the Pacific3 enrolled1 locationNCT07212803
Recruiting
Phase 4

Low- and Moderate-intensity Statin and Clinical Outcome of Primary Prevention in Individuals Aged >70 Years: the SCOPE-70 RCT Study

Healthy Elderly Individuals With High LDL-cholesterol or Risk of Cardiovascular Disease
Yonsei University724 enrolled1 locationNCT03770312
Recruiting
Phase 4

Pharmacokinetic Study of Allisartan Isoproxil Tablets in Healthy Chinese Participants

Healthy Participants
Shenzhen Salubris Pharmaceuticals Co., Ltd.54 enrolled1 locationNCT07174830
Recruiting
Phase 4

Characterizing the Human Airway Immune Response to FluMist Vaccination

Healthy Young AdultsInfluenza VaccinesInfluenza Vaccine Response
Washington University School of Medicine30 enrolled1 locationNCT07177417
Recruiting
Phase 4

Effect of Endurance Training-Induced Coenzyme Q10 (CoQ10) Supplementation on Myokine, Exerkine Secretion and Cognitive Functions in Long-Distance Runners

Health Knowledge, Attitudes, Practice
Gdansk University of Physical Education and Sport24 enrolled1 locationNCT06619249
Recruiting
Phase 4

Integrated e-Health (Electronic Health) for HIV and Substance Use Disorders in Justice Involved Women

Opioid-use DisorderHIVeHealth
Yale University250 enrolled2 locationsNCT05547048
Completed
Phase 4

Assessment of the Effects of Nebulised Dexmedetomidine for Premedication on Inflammatory and Oxidative Stress Response in Children Undergoing Tonsillotomy and Adenoidectomy: A Pilot Study

Other mental health disordersAnxiety
Mother and Child Health Institute Serbia, Belgrade, Serbia - Vesna Stevanovic30 enrolled1 locationACTRN12625000041459
Recruiting
Phase 4

Effects of Caffeine on Reinforcement Learning in Healthy Adults Using PET/MRI

HealthyCaffeineAdenosine+1 more
Hsiao-Ying Wey12 enrolled1 locationNCT06763172
Recruiting
Phase 4

The Effects of Acute Melatonin Supplementation on Cardiovascular Responses to Sympathetic Activation

Healthy
University of Oklahoma100 enrolled1 locationNCT04831398