Phase 4 Heart Failure Clinical Trials
59 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 59 trials
Recruiting
Phase 4
Optimized Treatment of Pulmonary Edema or Congestion
Congestive Heart FailurePulmonary EdemaAcute Heart Failure
Rigshospitalet, Denmark1,104 enrolled4 locationsNCT05276219
Recruiting
Phase 4
Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure
Heart FailureChronic Lymphocytic Leukaemia
AstraZeneca60 enrolled23 locationsNCT06651970
Recruiting
Phase 4
Mechanistic Clinical Trial Comparing the Pharmacokinetics/Pharmacodynamics of Metoprolol in Heart Failure With Reduced Ejection Fraction Patients With Low vs. High Polygenic Score
Heart Failure With Reduced Ejection Fraction
University of Michigan100 enrolled1 locationNCT07490067
Recruiting
Phase 4
Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure
Heart FailureCardiogenic ShockKetone Body Metabolism+2 more
Institute for Clinical and Experimental Medicine12 enrolled1 locationNCT07527156
Recruiting
Phase 4
Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure
Heart FailureHeart Failure AcuteAcute Heart Failure (AHF)+1 more
Lakeland Regional Health Systems, Inc.600 enrolled1 locationNCT07263035
Recruiting
Phase 4
The Assessment of Partial Guideline-Directed Medical Therapy Down Titration in Heart Failure in Remission.
Heart Failure
Ziekenhuis Oost-Limburg100 enrolled1 locationNCT07513883
Recruiting
Phase 4
The STOP-MED CTRCD Trial
Heart FailureCancerCardiotoxicity+2 more
Dinesh Thavendiranathan335 enrolled14 locationsNCT06183437
Recruiting
Phase 4
Effects of SGLT2 Inhibitors in Pre-heart Failure Populations With Hypertension
HypertensionPre-Heart Failure
China National Center for Cardiovascular Diseases120 enrolled2 locationsNCT06055452
Recruiting
Phase 4
Impact of Intravenous Iron Repletion On Mechanisms of Exercise InTolerance in HFpEF (IRONMET-HFpEF)
Iron-deficiencyHeart Failure With Preserved Ejection Fraction
Massachusetts General Hospital66 enrolled1 locationNCT04945707
Recruiting
Phase 4
Unmitigated Aldosterone Signaling During Standard Clinical MRA Dosing
Heart Failure
Yale University20 enrolled1 locationNCT07281014
Recruiting
Phase 4
Vericiguat and Reverse Remodeling Indices in Heart Failure
Heart Failure With Reduced Ejection Fraction (HFrEF)Chronic Heart Failure
University Medical Centre Ljubljana60 enrolled1 locationNCT07405944
Recruiting
Phase 4
Efficacy and Safety With Early Treatment of Finerenone in Hospitalized Patients With Heart Failure
Acute Heart Failure
Juntendo University550 enrolled21 locationsNCT07397650
Recruiting
Phase 4
Digoxin After Acute Heart Failure
Acute Heart Failure (AHF)
Guillermo Liniado120 enrolled1 locationNCT07321509
Recruiting
Phase 4
ENAVOgliflozin Outcome Trial in Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Replacement
Heart FailureAortic Valve Stenosis
Duk-Woo Park, MD1,040 enrolled31 locationsNCT05672836
Recruiting
Phase 4
The Prevalence of Iron Deficiency and the Effectiveness of Ferinject® in Patients With HFpEF (ID-HFpEF)
Chronic Heart FailureIron Deficiency, Latent
Tomsk National Research Medical Center of the Russian Academy of Sciences100 enrolled1 locationNCT05793996
Recruiting
Phase 4
Single and Twice-daily Dosing of Ramipril on Renal Function in Chronic Kidney Disease Patients With Reduced Ejection Fraction Heart Failure
Chronic Kidney DiseaseHeart Failure With Reduced Ejection Fraction (HFrEF)
Evi Liliek Wulandari80 enrolled1 locationNCT07259512
Recruiting
Phase 4
Gator SCALES-WHF: SubCutaneous Administration of Lasix to Eliminate Symptoms of Worsening Heart Failure
Heart FailureVolume Overload
University of Florida100 enrolled1 locationNCT06979726
Recruiting
Phase 4
Efficacy Of Sodium Glucose Transporter Inhibitor (SGLT2I) In Adult Patients With Congenital Heart Disease
Heart FailureAdult Congenital Heart Disease
Anita Saraf40 enrolled3 locationsNCT06260059
Recruiting
Phase 4
Effect of Oral sucRosomIal Iron on exerciSE Capacity and Quality of Life in Patients With Heart Failure
Iron-deficiencyChronic Heart FailureLeft Ventricular Systolic Dysfunction
Raffaele De Caterina60 enrolled1 locationNCT06270498
Recruiting
Phase 4
Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator
CardiomyopathySudden Cardiac DeathHeart Failure With Reduced Ejection Fraction (HFrEF)+3 more
University of Rochester2,000 enrolled13 locationsNCT06964464