Heart Clinical Trials in St Louis, Missouri
31 recruitingSt Louis, Missouri
Showing 1–20 of 31 trials
Recruiting
Phase 3
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Heart Failure
Boehringer Ingelheim6,000 enrolled653 locationsNCT06424288
Recruiting
Phase 3
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Heart Failure
Boehringer Ingelheim4,200 enrolled638 locationsNCT06935370
Recruiting
Phase 2Phase 3
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Heart FailureLeft Ventricular Systolic Dysfunction
Merck Sharp & Dohme LLC342 enrolled105 locationsNCT05714085
Recruiting
Phase 3
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
Left Ventricular Systolic DysfunctionHeart Failure (Pediatric)
Bayer111 enrolled133 locationsNCT07188805
Recruiting
Phase 1
A Safety, Tolerability, and Biomarker Trial of VS-041 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
Heart
Vasa Therapeutics42 enrolled21 locationsNCT07219511
Recruiting
Phase 3
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
Heart Failure
AstraZeneca11,300 enrolled928 locationsNCT06677060
Recruiting
Phase 3
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
CardiomyopathiesAmyloidosisHeart Diseases+3 more
Eidos Therapeutics, a BridgeBio company582 enrolled98 locationsNCT06563895
Recruiting
Not Applicable
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
Heart FailureCardiovascular DiseasesHeart Diseases
BrioHealth Solutions, Inc.780 enrolled37 locationsNCT06310031
Recruiting
Not Applicable
XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)
Heart FailureHeart TransplantTransplant; Failure, Heart
XVIVO Perfusion60 enrolled14 locationsNCT06895070
Recruiting
Phase 2
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
Heart Failure
Novo Nordisk A/S200 enrolled109 locationsNCT06979362
Recruiting
Phase 3
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Heart FailureHeart Failure With Reduced Ejection Fraction
Cytokinetics1,800 enrolled183 locationsNCT06736574
Recruiting
Not Applicable
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
Heart FailureHeart Failure NYHA Class IIIHeart Failure NYHA Class II
Endotronix, Inc.1,750 enrolled49 locationsNCT05934487
Recruiting
Phase 2
AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
Symptomatic Heart Failure With Preserved Ejection Fraction (HFpEF)
Cytokinetics60 enrolled24 locationsNCT06793371
Recruiting
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
Heart FailureArrhythmiaBradycardia+1 more
Medtronic20,000 enrolled318 locationsNCT00271180
Recruiting
Phase 2
Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
Heart Failure
Bristol-Myers Squibb208 enrolled117 locationsNCT06122779
Recruiting
Not Applicable
Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study
Heart Failure With Reduced Ejection Fraction (HFrEF)Dilated Cardiomyopathy
Ancora Heart, Inc.400 enrolled132 locationsNCT04331769
Recruiting
Phase 3
Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)
Acute Decompensated Heart Failure
Reprieve Cardiovascular, Inc400 enrolled53 locationsNCT06898515
Recruiting
Phase 2
Study of JK07 in Patients With Chronic Heart Failure
Heart Failure With Reduced Ejection FractionHeart Failure With Preserved Ejection Fraction
Salubris Biotherapeutics Inc282 enrolled62 locationsNCT06369298
Recruiting
Phase 2
The Inorganic Nitrate and eXercise Performance in Heart Failure (iNIX-HF)
Heart Failure
Washington University School of Medicine75 enrolled1 locationNCT05562167
Recruiting
Phase 1Phase 2
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction
Heart FailureCongestive Heart FailureHFrEF - Heart Failure With Reduced Ejection Fraction+1 more
Sardocor Corp.57 enrolled5 locationsNCT04703842