Phase 3 Hepatocellular Carcinoma Clinical Trials
40 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 40 trials
Recruiting
Phase 3
DEB-TACE vs cTACE in HCC After TIPS
Hepatocellular Carcinoma (HCC)TACETIPS+2 more
First Affiliated Hospital, Sun Yat-Sen University206 enrolled1 locationNCT07322848
Recruiting
Phase 2Phase 3
A Study to Evaluate the Efficacy and Safety of IBI310 and Sintilimab Combination Therapy in Patients With Hepatocellular Carcinoma as First-line Treatment.
Hepatocellular Carcinoma (HCC)
Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD.680 enrolled2 locationsNCT07490262
Recruiting
Phase 3
TACE Plus Camrelizumab and Apatinib for Unresectable Hepatocellular Carcinoma
Unresectable Hepatocellular CarcinomaApatinibCamrelizumab+1 more
Guohui Xu101 enrolled1 locationNCT06485466
Recruiting
Phase 2Phase 3
Comparison of SBRT and SIRT With Combination IO for Locally-advanced, Unresectable HCCs (BIIRTH)
Hepatocellular Carcinoma (HCC)
Tuen Mun Hospital106 enrolled1 locationNCT07293468
Recruiting
Phase 3
Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial
Stage III Hepatocellular Carcinoma AJCC v8Stage IV Hepatocellular Carcinoma AJCC v8Advanced Hepatocellular Carcinoma
NRG Oncology226 enrolled107 locationsNCT07166406
Recruiting
Phase 3
Adjuvant TACE in HCC With High-risk Recurrence Factors
Hepatocellular CarcinomaAdjuvantTransarterial Chemoembolization
Guangxi Medical University442 enrolled1 locationNCT07417397
Recruiting
Phase 2Phase 3
Durvalumab and Tremelimumab With or Without Hepatic Arterial Infusion of Chemotherapy in Hepatocellular Carcinoma
Hepatocellular Carcinoma
UNICANCER196 enrolled11 locationsNCT06904170
Recruiting
Phase 3
Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma
Hepatocellular Carcinoma
AstraZeneca1,220 enrolled204 locationsNCT06921785
Recruiting
Phase 2Phase 3
The Efficacy of Sequential Treatment With Bevacizumab Combined With Atezolizumab in Advanced Liver Cancer With MASLD
HCC - Hepatocellular Carcinoma
Eastern Hepatobiliary Surgery Hospital20 enrolled1 locationNCT07285850
Recruiting
Phase 3
Study of ADI-PEG 20 Versus Placebo in Subjects With High Arginine Level and Unresectable Hepatocellular Carcinoma
Hepatocellular CarcinomaAdvanced Hepatocellular Carcinoma
Polaris Group300 enrolled11 locationsNCT05317819
Recruiting
Phase 3
Infusional FOLFOX Plus Camrelizumab and Apatinib vs HAIC-FOLFOX Plus Camrelizumab and Apatinib for Advanced HCC
Chemotherapy EffectBCLC Stage C Hepatocellular Carcinoma
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University262 enrolled1 locationNCT06172205
Recruiting
Phase 2Phase 3
A Prospective Study of Memantine in Patients With Cirrhosis and Liver Cancer
Hepatocellular CarcinomaCirrhosis
Inova Health Care Services12 enrolled2 locationsNCT06007846
Recruiting
Phase 2Phase 3
Single-arm Clinical Trial of TACE in Combination With Icaritin as Adjuvant Therapy After Surgery in Patients With Hepatocellular Carcinoma at High Risk of Recurrence
Hepatocellular Carcinoma (HCC)
Zhujiang Hospital30 enrolled1 locationNCT06644937
Recruiting
Phase 3
Adjuvant Radiotherapy of Sintilimab Versus TACE for HCC
Radiotherapy, AdjuvantHepatocellular Carcinoma (HCC)Immune Checkpoint Inhibitor+2 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences286 enrolled1 locationNCT07186621
Recruiting
Phase 2Phase 3
A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)
Hepatocellular Carcinoma
AbbVie660 enrolled37 locationsNCT06109272
Recruiting
Phase 3
Continuation of First-line Therapy With Radiotherapy Versus Early Switch to Second-line Therapy in Oligoprogressive HCC
RadiotherapyOligoProgressive Metastatic DiseaseHepatocellular Carcinoma (HCC)+1 more
Shandong Cancer Hospital and Institute132 enrolled1 locationNCT06841172
Recruiting
Phase 3
Evaluating Novel Therapies in ctDNA Positive GI Cancers
Hepatocellular CarcinomaGastric AdenocarcinomaPancreatic Adenocarcinoma+4 more
Georgetown University20 enrolled3 locationsNCT05482516
Recruiting
Phase 3
Chinese HCC Efficacy Evaluation, Response and Safety Study of TareSphere
Unresectable Hepatocellular Carcinoma
Chengdu New Radiomedicine Technology Co. LTD.108 enrolled11 locationsNCT06900543
Recruiting
Phase 3
Study of SHR-8068 Combined With Adebrelimab and Bevacizumab Versus Sintilimab Combined With Bevacizumab for the Treatment of Advanced Hepatocellular Carcinoma
Advanced Hepatocellular Carcinoma
Suzhou Suncadia Biopharmaceuticals Co., Ltd.590 enrolled1 locationNCT06618664
Recruiting
Phase 3
Namodenoson in the Treatment of Advanced Hepatocellular Carcinoma in Patients With Child-Pugh Class B7 Cirrhosis
Hepatocellular CarcinomaCirrhosis
Can-Fite BioPharma471 enrolled32 locationsNCT05201404