Early Phase 1 HIES Clinical Trials
12 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–12 of 12 trials
Recruiting
Early Phase 1
Study of Biodistribution, Metabolism, Excretion and Brain Uptake11C-M503
Tauopathies
University of Pennsylvania70 enrolled3 locationsNCT06303921
Recruiting
Early Phase 1
Efficacy of a Topical Palmitated Formulation of Capsaicin (Capsadyn®) In the Treatment of Diabetic Neuropathic Foot Pain
Diabetic FootDiabetic Peripheral NeuropathyDiabetic Neuropathies, Painful
Carilion Clinic80 enrolled1 locationNCT07260656
Recruiting
Early Phase 1
MTS109 in Patients With Refractory Autoimmune Diseases
Systemic Lupus ErythematosusIdiopathic Inflammatory MyopathiesSystemic Sclerosis (SSc)+2 more
Shanghai Changzheng Hospital15 enrolled1 locationNCT07526350
Recruiting
Early Phase 1
A Study of CC312 for Relapsed/Refractory Autoimmune Diseases
SLE - Systemic Lupus ErythematosusSSc-Systemic SclerosisIIM- Idiopathic Inflammatory Myopathies
CytoCares Inc6 enrolled1 locationNCT07193810
Recruiting
Early Phase 1
Clinical Study on Targeted CD19 or CD19-BCMA CAR-T Therapy for Autoimmune Diseases
Sjogren's SyndromeAutoimmune DiseasesIdiopathic Inflammatory Myopathies+3 more
Nanjing Bioheng Biotech Co., Ltd.20 enrolled1 locationNCT06548607
Recruiting
Early Phase 1
Efficacy and Safety of Pozelimab and Cemdisiran Combination Therapy in Patients With Sporadic Inclusion Body Myositis
Idiopathic Inflammatory MyopathiesSporadic Inclusion Body Myositis (sIBM)
Austin Neuromuscular Center10 enrolled2 locationsNCT06479863
Recruiting
Early Phase 1
Study of Biodistribution, Metabolism, Excretion and Brain Uptake 18F-JSS20-183A
Tauopathies
University of Pennsylvania90 enrolled2 locationsNCT06932809
Recruiting
Early Phase 1
Study of Biodistribution, Metabolism, Excretion and Brain Uptake of 11C-HY-2-15
Tauopathies
University of Pennsylvania70 enrolled1 locationNCT06032026
Recruiting
Early Phase 1
An Exploratory Study of CD19/CD22/BCMA CAR-T Cells (BZE2204) in Subjects With Relapsed or Refractory Autoimmune Diseases
Systemic Lupus Erythematosus (SLE)Immune Thrombocytopenia (ITP)Idiopathic Inflammatory Myopathies(IIM)
Shanghai Cell Therapy Group Co.,Ltd20 enrolled1 locationNCT07174843
Recruiting
Early Phase 1
[18F]ACI-19626 PET in TDP-43 Proteinopathies
Amyotrophic Lateral Sclerosis(ALS)Alzheimer's Disease(AD)Frontotemporal Dementia (FTD)+2 more
AC Immune SA45 enrolled1 locationNCT06891716
Recruiting
Early Phase 1
Safety and Efficacy of CT103A Cells for Relapsed/Refractory Antibody-associated Inflammatory Diseases of the Nervous System
Myasthenia GravisAutoimmune EncephalitisMultiple Sclerosis+7 more
Tongji Hospital36 enrolled1 locationNCT04561557
Recruiting
Early Phase 1
Safety and Efficacy of RM-004 Cells for Hemoglobin H-Constant Spring Disease
Hereditary DiseasesHemoglobinopathiesAlpha Thalassemia Hemoglobin H Constant Spring
The 923rd Hospital of Joint Logistics Support Force of People's Liberation Army5 enrolled1 locationNCT06107400