HIES Clinical Trials

229 recruitingLast updated: May 21, 2026

There are 229 actively recruiting hies clinical trials across 53 countries. Studies span Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 3, Phase 4. Top locations include Philadelphia, Pennsylvania, United States, Boston, Massachusetts, United States, New York, New York, United States. Updated daily from ClinicalTrials.gov.


HIES Trials at a Glance

229 actively recruiting trials for hies are listed on ClinicalTrialsFinder across 6 cities in 53 countries. The largest study group is Not Applicable with 53 trials, with the heaviest enrollment activity in Philadelphia, Boston, and New York. Lead sponsors running hies studies include University of Pennsylvania, Shanghai Changzheng Hospital, and Children's Hospital of Philadelphia.

About HIES Clinical Trials

Looking for clinical trials for HIES? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new HIES trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about HIES clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 229 trials

Recruiting
Phase 1

Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis

Atopic DermatitisLupusHyper IgE Syndrome From STAT3 Mutation+2 more
National Institute of Allergy and Infectious Diseases (NIAID)20 enrolled1 locationNCT07262983
Recruiting
Phase 2

Phase 2 Study of Rapcabtagene Autoleucel in Myositis

Idiopathic Inflammatory Myopathies
Novartis Pharmaceuticals123 enrolled58 locationsNCT06665256
Recruiting
Phase 2

Phase 2 Study of SAT-3247 in Pediatric Ambulatory Patients

Duchenne Muscular DystrophyDMDNeuromuscular Diseases+2 more
Satellos Bioscience, Inc.51 enrolled21 locationsNCT07287189
Recruiting
Phase 3

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

CardiomyopathiesAmyloidosisHeart Diseases+3 more
Eidos Therapeutics, a BridgeBio company587 enrolled101 locationsNCT06563895
Recruiting
Phase 2

Drug Rediscovery for Rare Immune Mediated Inflammatory Diseases

Behcet's DiseaseIdiopathic Inflammatory MyopathiesIgG4-related Disease
UMC Utrecht60 enrolled6 locationsNCT06285539
Recruiting
Phase 1

Safety and Pharmacodynamics of QH103 Cell Injection in the Treatment of Patients With Relapsed/Refractory Antibody-Mediated Neurological Autoimmune Diseases.

Neuromyelitis Optica Spectrum Disorder (NMOSD)Multiple Sclerosis (MS)Myasthenia Gravis (MG)+4 more
Tongji Hospital6 enrolled1 locationNCT07526493
Recruiting
Phase 1

A Phase 1 Open-label Study to Evaluate Safety in Healthy Participants and Participants With Autoimmune Diseases

HealthyIdiopathic Inflammatory MyopathiesSystemic Sclerosis+1 more
Xencor, Inc.60 enrolled1 locationNCT07284797
Recruiting

Noninvasive Cardiovascular Diagnosis of Patients With Fully Magnetically Levitated Blood Pumps

CardiomyopathiesEnd-stage Heart FailureMechanical Circulatory Support
Thomas Schlöglhofer, PhD, MSc60 enrolled1 locationNCT04641416
Recruiting

Analysis of the Genotype/Phenotype Relationship in the Fuchs' Corneal Endothelial Dystrophy in France

Corneal Dystrophies
Centre Hospitalier Universitaire de Saint Etienne500 enrolled1 locationNCT05742321
Recruiting
Not Applicable

Electrical Impedance Myography: Natural History Studies inNeuromuscular Disorders and Healthy Volunteers

Motor Neuron DiseaseInherited Neuromuscular ConditionsInherited Neuropathies+1 more
National Institute of Neurological Disorders and Stroke (NINDS)275 enrolled1 locationNCT01900132
Recruiting
Phase 1

A Study of AZD0120 in Autoimmune Diseases

Rheumatoid ArthritisIdiopathic Inflammatory MyopathiesSystemic Sclerosis
AstraZeneca27 enrolled18 locationsNCT07295847
Recruiting
Not Applicable

ECoG BMI for Motor and Speech Control

StrokeMultiple SclerosisALS+2 more
Karunesh Ganguly3 enrolled1 locationNCT03698149
Recruiting

Discarded Bone Marrow for Hematology Research

Hemoglobinopathies
St. Jude Children's Research Hospital50 enrolled1 locationNCT04671212
Recruiting
Phase 1Phase 2

Cannabidiol for the Treatment of Diabetic Peripheral Neuropathy: Pilot Study

Diabetic NeuropathiesDiabetic Peripheral Neuropathic Pain (DPN)
Florida A&M University20 enrolled1 locationNCT07298408
Recruiting

Clinical Characteristics and Mechanism Research of Deucravacitinib in the Idiopathic Inflammatory Myopathies

Idiopathic Inflammatory Myopathies (IIMs)
Peking University People's Hospital10 enrolled1 locationNCT07564271
Recruiting
Phase 1

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.

Rheumatoid ArthritisSystemic Lupus ErythematosusIdiopathic Inflammatory Myopathies
AstraZeneca72 enrolled35 locationsNCT06916806
Recruiting
Early Phase 1

Study of Biodistribution, Metabolism, Excretion and Brain Uptake11C-M503

Tauopathies
University of Pennsylvania70 enrolled3 locationsNCT06303921
Recruiting

Mayo AVC Registry and Biobank

CardiomyopathiesCardiovascular DiseasesSarcoidosis+14 more
Mayo Clinic1,000 enrolled2 locationsNCT03049254
Recruiting

Study of Axial and Cognitive Symptoms and Biomarkers of Neurodegeneration in Brain-first and Body-first PD

Parkinson DiseaseBrain DiseaseSynucleinopathies+2 more
Azienda USL Reggio Emilia - IRCCS150 enrolled1 locationNCT07187843
Recruiting
Early Phase 1

Efficacy of a Topical Palmitated Formulation of Capsaicin (Capsadyn®) In the Treatment of Diabetic Neuropathic Foot Pain

Diabetic FootDiabetic Peripheral NeuropathyDiabetic Neuropathies, Painful
Carilion Clinic80 enrolled1 locationNCT07260656