Phase 2 High-risk Prostate Cancer Clinical Trials
7 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–7 of 7 trials
Recruiting
Phase 2
Neoadjuvant ADT + Darolutamide With Pembrolizumab, Followed by Adjuvant Pembrolizumab in Molecularly Stratified High-Risk Prostate Cancer
Prostate CancerHigh-risk Prostate Cancer
Icahn School of Medicine at Mount Sinai40 enrolled1 locationNCT07027124
Recruiting
Phase 2
Androgen-responsive POSLUMA-guided Intra-prostatic Boost
Prostate CancerHigh-risk Prostate CancerIntermediate Risk Prostate Cancer
Martin T. King, MD, PhD23 enrolled4 locationsNCT07393867
Recruiting
Phase 2
A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN Loss
High-risk Prostate Cancer
VA Office of Research and Development30 enrolled6 locationsNCT05593497
Recruiting
Phase 1Phase 2
Tb-PSMA-I&T Radionuclide Before Radical Prostatectomy in Patients With Locally Advanced Prostate Cancer - TbeforePROST Trial.
High-risk Prostate Cancer
Rabin Medical Center20 enrolled1 locationNCT07208240
Recruiting
Phase 2
Surgical Treatment With or Without Apalutamide in Subjects With High Risk Prostate Cancer Who Are Candidates for Radical Prostatectomy and Staged as Oligometastatic With PSMA-PET
High-risk Prostate Cancer
Marco Oderda94 enrolled1 locationNCT06758882
Recruiting
Phase 2
FK-PC101 as Adjuvant Therapy for Men With High-Risk Prostate Cancer
Prostate CancerProstate CancersProstate Cancer (Adenocarcinoma)+4 more
Cellvax Therapeutics Inc100 enrolled3 locationsNCT06636682
Recruiting
Phase 2
Neoadjuvant Intense Endocrine Therapy for High Risk and Locally Advanced Prostate Cancer
Neoadjuvant TherapyHigh-risk Prostate CancerLocally Advanced Prostate Cancer+1 more
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School900 enrolled1 locationNCT05406999