Phase 1 Human Papillomavirus Clinical Trials

8 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 18 of 8 trials

Recruiting
Phase 1

Testing RG1-VLP Vaccine to Prevent HPV-related Cancers

Human Papillomavirus-Related Carcinoma
National Cancer Institute (NCI)18 enrolled5 locationsNCT05985681
Recruiting
Phase 1

Decitabine in Combination With Standard of Care Therapy for the Treatment of Surgically Resectable HPV-Negative Head and Neck Cancer

Resectable Head and Neck Squamous Cell CarcinomaHuman Papillomavirus-Negative Neck Squamous Cell CarcinomaResectable Human Papillomavirus-Independent Head and Neck Mucosal Squamous Cell Carcinoma+1 more
Mayo Clinic24 enrolled1 locationNCT06997094
Recruiting
Phase 1

HPV DNA Vaccine Via Electroporation for HPV16 Positive Cervical Neoplasia

Human Papillomavirus Type 16Cervical Intraepithelial Neoplasia Grade IICervical Intraepithelial Neoplasia, Grade III
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins48 enrolled2 locationsNCT04131413
Recruiting
Phase 1Phase 2

Effect of Honey For CIN II

Cervical Intraepithelial Neoplasia-IIHigh Risk Human Papillomavirus
Zuyderland Medisch Centrum60 enrolled2 locationsNCT06219018
Recruiting
Phase 1Phase 2

HUC-MSC for Treatment of High-risk HPV Infection

Human Papillomavirus VirusesMesenchymal Stem Cells
Shanghai East Hospital60 enrolled1 locationNCT06610773
Recruiting
Phase 1

SCG142 TCR-T Cells for Human Papillomavirus-Associated Carcinomas

Cervical CancerAnal CancerPenile Cancer+5 more
The Affiliated Hospital of Qingdao University18 enrolled1 locationNCT06544720
Not Yet Recruiting
Phase 1

A study comparing Brincidofovir administered as an oral suspension versus Intravenous Formulation in Japanese and Non-Japanese Adult Volunteers

Viral Infection - orthopoxvirusesViral Infection - polyomavirusesViral Infection - human herpesviruses (HHV)+2 more
Chimerix Inc.36 enrolled1 locationACTRN12618002011268
Not Yet Recruiting
Phase 1

Efficacy of iodine solution administered via a treatment applicator for treating human papillomavirus (HPV) infection of the cervix.

Cervical human papillomavirus infection
Jenny McClloskey60 enrolled1 locationACTRN12617000726358