Phase 2 Human Papillomavirus Clinical Trials

8 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 18 of 8 trials

Recruiting
Phase 2

De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 ctHPV-DNA

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+4 more
Mayo Clinic455 enrolled3 locationsNCT05541016
Recruiting
Phase 2

Phase II Trial of Neoadjuvant Chemotherapy (NAC) Alone or in Combination With Immunotherapy Vaccine PRGN-2009 in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal (Head and Neck) Cancer

Squamous Cell Carcinoma of the Head and NeckDrug TherapyOropharynx+2 more
National Cancer Institute (NCI)70 enrolled1 locationNCT06223568
Recruiting
Phase 2

Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN)

Head and Neck CancerLaryngeal CancerOral Cavity Cancer+6 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins75 enrolled1 locationNCT07209189
Recruiting
Phase 2

Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP Trial

Metastatic Head and Neck Squamous Cell CarcinomaRecurrent Head and Neck Squamous Cell CarcinomaClinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+19 more
Emory University28 enrolled2 locationsNCT06636734
Recruiting
Phase 1Phase 2

Effect of Honey For CIN II

Cervical Intraepithelial Neoplasia-IIHigh Risk Human Papillomavirus
Zuyderland Medisch Centrum60 enrolled2 locationsNCT06219018
Recruiting
Phase 2

Vaccination Against Human Papillomavirus (HPV) After Allogeneic Stem Cell Transplantation

Myelodysplastic SyndromeDiffuse Large B-Cell Lymphoma (DLBCL)Acute Myeloid Leukaemia+2 more
Vastra Gotaland Region100 enrolled5 locationsNCT06793410
Recruiting
Phase 2

HPV Vaccine, Imiquimod, and Metformin Combination Trial

Cervical CarcinomaVaginal CarcinomaVulvar Carcinoma+1 more
Baylor College of Medicine85 enrolled2 locationsNCT06686043
Recruiting
Phase 1Phase 2

HUC-MSC for Treatment of High-risk HPV Infection

Human Papillomavirus VirusesMesenchymal Stem Cells
Shanghai East Hospital60 enrolled1 locationNCT06610773