Phase 4 Human Clinical Trials
17 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–17 of 17 trials
Recruiting
Phase 4
Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking Cessation Package for Smokers in HIV Clinical Care
Smoking CessationHuman Immunodeficiency Virus (HIV)
New York University500 enrolled1 locationNCT06598397
Recruiting
Phase 4
Low Dose Naltrexone for Pain in Patients With HIV
Human Immunodeficiency VirusChronic Neuropathic Pain
Emory University60 enrolled3 locationsNCT05537935
Recruiting
Phase 4
A Study to Assess the Reduction of Human Papillomavirus (HPV) Viral Infectivity and Transmission in HPV-Positive Women After Vaccination With 9vHPV (RIFT-HPV)
Cervical Intraepithelial Neoplasia Grade I/ II/ III (CIN I/II/III)Human Papillomavirus (HPV) InfectionsHigh-risk HPV+1 more
Miquel Angel Pavon Ribas69 enrolled1 locationNCT05334706
Recruiting
Phase 4
Characterization of Humoral and Cellular Immune Responses Elicited by Influenza Vaccination in Healthy Adults
Influenza, Human
University of Pennsylvania700 enrolled1 locationNCT05108818
Recruiting
Phase 4
A Study of Reduced Dosing of the Nonavalent HPV Vaccine in Women Living With HIV
Human Papilloma VirusHPVHuman Immunodeficiency Virus
University of British Columbia275 enrolled10 locationsNCT05495906
Recruiting
Phase 4
Comparing Immune Response of 2 vs 3 HPV Doses (27-45 Years Old)
Human PapillomavirusHPV InfectionImmunization
The University of Texas Medical Branch, Galveston618 enrolled1 locationNCT05672927
Recruiting
Phase 4
Tfh Dysfunction in HIV and Aging
Human Influenza
University of Miami400 enrolled1 locationNCT04487041
Recruiting
Phase 4
Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIV
Papillomavirus InfectionHuman Immunodeficiency VirusCervical Intraepithelial Neoplasia+4 more
Louisiana State University Health Sciences Center in New Orleans250 enrolled1 locationNCT05266898
Recruiting
Phase 4
Study of 2LPAPI® on the Clearance of Genital HR-HPV Infections.
Human Papilloma Virus
Labo'Life284 enrolled12 locationsNCT04232917
Terminated
Phase 3Phase 4
Reactogenicity Study of Afluria Quad/Afluria Quad Junior in Children
Influenza, Humans
Seqirus1,800 enrolled1 locationACTRN12619000792123
Recruiting
Phase 4
The impact of Clonidine, a pharmacological treatment for attention deficit hyperactivity disorder (ADHD), on behavioural and brain imaging measures of attention, inhibition and error processing.
Study employs a commonly used ADHD medication (Clonidine) with healthy human adults (only) and examines changes in behaviours that are of relevance to ADHD (inhibition, error processing, selective attention)
Professor Mark Bellgrove26 enrolled1 locationACTRN12615000093583
Completed
Phase 4
The pharmacokinetics of intranasal droperidol in healthy volunteers.
Pharmacokinetics of intranasal drug delivery in healthy human volunteers.
Monash Health7 enrolled1 locationACTRN12614000514606
Completed
Phase 4
Effects of inhaled methoxyflurane (Penthrox) on psychomotor function in humans: a randomized placebo trial
Psychomotor function in humans who inhale methoxyflurane (Penthrox) as a mode of analgesia
Department of Gastroenterology and Hepatology, Royal Adelaide Hospital60 enrolled1 locationACTRN12613000666729
Completed
Phase 4
Vitamin D Deficiency in Human Immunodeficiency Virus
Human Immundeficiency InfectionVitamin D Deficiency
The Alfred Hospital Research Trust40 enrolled1 locationACTRN12611000631909
Active
Phase 4
A randomised open-label study comparing the safety and efficacy of ritonavir boosted lopinavir and 2-3 nucleoside reverse transcriptase inhibitors (NRTI) backbone versus ritonavir boosted lopinavir and raltegravir in participants virologically failing first-line non-nucleoside reverse transcriptase inhibitors (NNRTI)/2 NRTI therapy (the SECOND-LINE study). This study is for Human Immunodeficiency Virus (HIV) infection.
Human Immunodeficiency Virus (HIV) -1 infection
University of New South Wales/Kirby Institute550 enrolled31 locationsACTRN12609000881235
Completed
Phase 4
Comparative pharmacokinetics and pharmcodynamics of recombinant and urinary human chorionic gonadotrophin (rhCG vs uhCG)
Comparative pharmacological effects of two different preparations of human chorionic gonadotrophin (hCG) in men
Concord Repatriation General Hospital (CRGH)26 enrolled1 locationACTRN12609000462280
Completed
Phase 4
Cardiovascular function with switching from Kivexa to Truvada (or from Abacavir to Tenofovir).
Human Immunodeficiency Virus (HIV)Cardiovascular function
St Vincents Hospital20 enrolled1 locationACTRN12609000014257