Characterization of Humoral and Cellular Immune Responses Elicited by Influenza Vaccination in Healthy Adults
University of Pennsylvania
700 participants
Oct 7, 2021
INTERVENTIONAL
Conditions
Summary
Cellular and humoral immune responses before and after seasonal influenza vaccination will be assessed. Each year, up to 100 participants will be enrolled. To study age-specific differences in immune responses, participants with various years of birth will be enrolled. The investigators hypothesize that humans with different birth years will mount antibody and cellular responses of different specificities following seasonal influenza vaccination.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
The seasonal influenza vaccine is administered intramuscularly at a dose of 15 ug of HA per component, as approved by the FDA.
Locations(1)
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NCT05108818