Human Clinical Trials

3 recruiting

Human Trials at a Glance

209 actively recruiting trials for human are listed on ClinicalTrialsFinder across 6 cities in 56 countries. The largest study group is Not Applicable with 68 trials, with the heaviest enrollment activity in Atlanta, Houston, and Bethesda. Lead sponsors running human studies include National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID), and Mayo Clinic.

Treatments under study

About Human Clinical Trials

Looking for clinical trials for Human? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Human trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Human clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 209 trials

Recruiting

Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants

Sickle Cell DiseaseMalariaAlpha and Beta Thalassemia+1 more
National Institute of Allergy and Infectious Diseases (NIAID)300 enrolled1 locationNCT03937817
Recruiting
Phase 2

Phase II Trial of Neoadjuvant Chemotherapy (NAC) Alone or in Combination With Immunotherapy Vaccine PRGN-2009 in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal (Head and Neck) Cancer

Squamous Cell Carcinoma of the Head and NeckDrug TherapyOropharynx+2 more
National Cancer Institute (NCI)70 enrolled1 locationNCT06223568
Recruiting
Phase 2

Doravirine (DOR) in Human Immunodeficiency Virus (HIV)-Infected Children Aged 4 Weeks to <12 Years and <45 kg (MK-1439-066)

Human Immunodeficiency Virus (HIV) Infection
Merck Sharp & Dohme LLC84 enrolled24 locationsNCT04375800
Recruiting
Phase 2

A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat Cancer

Oropharyngeal CancerThroat CancerHuman Papilloma Virus+2 more
Memorial Sloan Kettering Cancer Center121 enrolled7 locationsNCT05491512
Recruiting
Phase 1Phase 2

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

Head and Neck Squamous Cell Carcinoma (HNSCC)Non-small Cell Lung Cancer (NSCLC)Pancreatic Adenocarcinoma+2 more
Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.230 enrolled13 locationsNCT05985655
Recruiting
Phase 2Phase 3

A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)

Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Merck Sharp & Dohme LLC570 enrolled47 locationsNCT07266831
Recruiting
Phase 2

Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN)

Head and Neck CancerLaryngeal CancerOral Cavity Cancer+6 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins75 enrolled1 locationNCT07209189
Recruiting

Harm Reduction in HIV Primary Care for PLWH Who Use Drugs

Substance UseHuman Immunodeficiency VirusStigma, Social
University of Pittsburgh768 enrolled3 locationsNCT05404750
Recruiting
Not Applicable

Transpulmonary Pressure - Guided Mechanical Ventilation in Morbidly Obese ARDS Patients: a Feasibility Study.

ARDS, HumanObesity, Morbid
Assistance Publique - Hôpitaux de Paris40 enrolled5 locationsNCT06119516
Recruiting
Phase 1

Lenacapavir Intensification to Disrupt HIV Reservoirs in Virologically Suppressed People With HIV Receiving Antiretroviral Therapy

Human Immunodeficiency Virus
National Institute of Allergy and Infectious Diseases (NIAID)50 enrolled1 locationNCT06819176
Recruiting

Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer

Kidney CancerKidney NeoplasmsPneumothorax+1 more
National Cancer Institute (NCI)950 enrolled1 locationNCT00033137
Recruiting
Not Applicable

Digital Telecytology for Triage of HPV-Positive Women in Cameroon

Human Papillomavirus InfectionCervical Cancer Screening MethodsCervical Intraepithelial Neoplasia Grade 2 (CIN2)
University Hospital, Geneva1,800 enrolled2 locationsNCT07550010
Recruiting
Not Applicable

Adaptation and Implementation of an Evidence-based Approach to Advance HIV Prevention and Care

HIV (Human Immunodeficiency Virus)StigmaContinuum of Care
University of California, Los Angeles80 enrolled1 locationNCT07495059
Recruiting
Early Phase 1

Merck IIT: RRP Pembro and Lenvatinib

Pulmonary DiseaseRecurrent Respiratory PapillomatosisHuman Papilloma Virus
Yale University20 enrolled1 locationNCT04645602
Recruiting

Natural History, Epidemiology and Pathogenesis of Severe HPV-Related Diseases (Neptune)

Human Papillomavirus
National Institute of Allergy and Infectious Diseases (NIAID)850 enrolled1 locationNCT05026138
Recruiting
Phase 2

BPL-1357 Against H1N1 Influenza Virus Challenge

HumanInfluenza
National Institute of Allergy and Infectious Diseases (NIAID)129 enrolled2 locationsNCT07215858
Recruiting
Phase 2

A Phase 2 Trial Comparing Antiviral Treatments in Early Symptomatic Influenza

InfluenzaInfluenza, Human
University of Oxford3,000 enrolled4 locationsNCT05648448
Recruiting
Phase 1

Testing RG1-VLP Vaccine to Prevent HPV-related Cancers

Human Papillomavirus-Related Carcinoma
National Cancer Institute (NCI)18 enrolled5 locationsNCT05985681
Recruiting

Multidimensional and Multimodal Profiling of Oropharyngeal Carcinoma

Human Papilloma VirusOropharyngeal Carcinoma
Stanford University1,000 enrolled1 locationNCT05880797
Recruiting
Phase 4

Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking Cessation Package for Smokers in HIV Clinical Care

Smoking CessationHuman Immunodeficiency Virus (HIV)
New York University500 enrolled1 locationNCT06598397