Hypersensitivity Clinical Trials

40 recruitingLast updated: June 19, 2026

There are 40 actively recruiting hypersensitivity clinical trials across 22 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 1, Early Phase 1, Phase 4. Top locations include Boston, Massachusetts, United States, Baltimore, Maryland, United States, Kansas City, Kansas, United States. Updated daily from ClinicalTrials.gov.


Hypersensitivity Trials at a Glance

40 actively recruiting trials for hypersensitivity are listed on ClinicalTrialsFinder across 6 cities in 22 countries. The largest study group is Not Applicable with 16 trials, with the heaviest enrollment activity in Boston, Baltimore, and Kansas City. Lead sponsors running hypersensitivity studies include HALEON, Assistance Publique - Hôpitaux de Paris, and Johns Hopkins University.

Browse hypersensitivity trials by phase

Treatments under study

About Hypersensitivity Clinical Trials

Looking for clinical trials for Hypersensitivity? There are currently 5 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Hypersensitivity trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Hypersensitivity clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 40 trials

Recruiting
Phase 2

Omalizumab for the Treatment of Food Allergy in Patients With Elevated Total IgE Levels

Food Hypersensitivity
Johns Hopkins University32 enrolled1 locationNCT06934200
Recruiting

Activation and Function of Eosinophils in Conditions With Blood or Tissue Eosinophilia

Immune System DiseasesEosinophiliaHelminthiasis+2 more
National Institute of Allergy and Infectious Diseases (NIAID)800 enrolled1 locationNCT00001406
Recruiting
Not Applicable

Effect of Fluoride Varnish Formulation on the Management of Dentin Hypersensitivity

Fluoride VarnishesHypersensitivity Dentin
University of Concepcion, Chile92 enrolled1 locationNCT07286344
Recruiting
Not Applicable

Reimagining Interventions for Support and Education in Hypersensitivity Pneumonitis

Hypersensitivity Pneumonitis
Weill Medical College of Cornell University42 enrolled1 locationNCT06811389
Recruiting
Phase 2

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing

antibiotic allergyDrug hypersensitivityCephalosporin Allergy+4 more
Massachusetts General Hospital300 enrolled6 locationsNCT06406114
Recruiting
Phase 1Phase 2

Novel Biomarkers of Non-IgE Immediate Hypersensitivity Drug Reactions

Healthy VolunteerVancomycinHypersensitivity Reactions
Johns Hopkins University25 enrolled1 locationNCT07605806
Recruiting
Not Applicable

Skeletal Muscle Function in Interstitial Lung Disease

Interstitial Lung DiseaseIdiopathic Pulmonary FibrosisScleroderma+2 more
University of British Columbia40 enrolled1 locationNCT03800017
Recruiting

P4O2 ILD Extension

Interstitial Lung DiseasePulmonary FibrosisIPF+7 more
Amsterdam UMC, location VUmc450 enrolled1 locationNCT06644144
Recruiting

Multi-site Study to Look at Tooth Wear and Tooth Sensitivity and the Risk Factors Associated.

Dentin HypersensitivityErosive Tooth Wear
Indiana University2,500 enrolled1 locationNCT07195357
Recruiting

A Study Evaluating Oral-Health-Related Quality of Life and Treatment Patterns Among Dentin Hypersensitivity Sufferers

Dentin Hypersensitivity
HALEON375 enrolled1 locationNCT07337109
Recruiting
Not Applicable

Hydroxyapatite-Based Home Treatment for Dentin Sensitivity in Celiac Patients

Dentin HypersensitivityCeliac DiseaseTooth Demineralization
University of Pavia40 enrolled1 locationNCT07069127
Recruiting

Origin and Function of Eosinophilic Polynuclear During DRESS Syndrome

Drug hypersensitivityDRESS Syndrome
University Hospital, Lille80 enrolled11 locationsNCT04330118
Recruiting
Phase 4

Inhaling Penehyclidine to Prevent Perioperative Respiratory Adverse Events in Children at Risk Undergoing Sevoflurane Anesthesia

Perioperative Respiratory Adverse EventsHigh-RiskRespiratory Hypersensitivity+2 more
Sun Yat-sen University204 enrolled2 locationsNCT06624696
Recruiting
Phase 2

A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis

Progressive Pulmonary FibrosisInterstitial Lung DiseasePulmonary Fibrosis+7 more
Avalyn Pharma Inc.375 enrolled152 locationsNCT06329401
Recruiting
Phase 1

Effects of Inhaled Epinephrine on Systemic Allergic Reactions During Allergy Testing, Immunotherapy or Oral Challenges

AnaphylaxisHypersensitivity
Dr. George Luciuk100 enrolled1 locationNCT07038746
Recruiting
Phase 3

Clinical Study to Investigate the Antihypersensitivity Efficacy of a Novel Dentifrice

Dentin Hypersensitivity
HALEON850 enrolled3 locationsNCT07215767
Recruiting
Not Applicable

Intraosseous vs Infiltration Anesthesia in Molar-Incisor Hypomineralization (MIH) Children

HypersensitivityMolar Incisor Hypomineralization
Ankara Yildirim Beyazıt University30 enrolled1 locationNCT07352813
Recruiting

SMASH: Study to Evaluate the Clinical Efficacy of an Extensively Hydrolysed Infant Formula With Synbiotics and a Human Milk Oligosaccharide (HMO) in Infants With Cow's Milk Protein Allergy (CMPA)

Gut MicrobiotaFood HypersensitivityCow's Milk Protein Allergy (CMPA)+1 more
Outcomes'1041 enrolled13 locationsNCT07342621
Recruiting
Not Applicable

Birth Cohort: Development of IgE Autoantibodies in Newborns With (High Risk of) Atopic Dermatitis

Allergic diseaseAtopic Dermatitis (AD)Autoantibody+4 more
Universitair Ziekenhuis Brussel500 enrolled1 locationNCT07316465
Recruiting
Not Applicable

Goat vs. Cow Milk Digestive Tolerance

milk intoleranceMilk HypersensitivityCow Milk Protein Sensitivity
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement20 enrolled1 locationNCT07239856