Hypertrophic Clinical Trials

1 recruiting

About Hypertrophic Clinical Trials

Looking for clinical trials for Hypertrophic? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Hypertrophic trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Hypertrophic clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 72 trials

Recruiting
Phase 2Phase 3

A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

PediatricSymptomatic Obstructive Hypertrophic Cardiomyopathy
Cytokinetics55 enrolled38 locationsNCT06412666
Recruiting
Phase 1Phase 2

Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM

Hypertrophic Cardiomyopathy
Tenaya Therapeutics30 enrolled10 locationsNCT05836259
Recruiting
Phase 2

Ademetionine in Obstructive Hypertrophic Cardiomyopathy

Obstructive Hypertrophic Cardiomyopathy (oHCM)
China National Center for Cardiovascular Diseases44 enrolled3 locationsNCT07367724
Recruiting

HCMR Re-Imaging Study

Hypertrophic Cardiomyopathy (HCM)
Christopher Kramer314 enrolled8 locationsNCT07054073
Recruiting

A Study to Assess the Real-World Effectiveness of Mavacamten in Adult Patients With Obstructive Hypertrophic Cardiomyopathy in China

Hypertrophic Cardiomyopathy
Bristol-Myers Squibb500 enrolled15 locationsNCT07361289
Recruiting
Phase 1Phase 2

Application of [68Ga]Ga-NI-FAPI-04 PET/CT Imaging in Fibroblast Activation Protein Related Diseases

TumorCardiovascular DiseasesPulmonary Fibrosis+3 more
Peking Union Medical College Hospital30 enrolled1 locationNCT07464132
Recruiting
Phase 4

A Study of Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India (ROVER)

Symptomatic Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb50 enrolled31 locationsNCT07004972
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy

Non-obstructive Hypertrophic CardiomyopathyObstructive Cardiomyopathy, Hypertrophic
Lexicon Pharmaceuticals500 enrolled107 locationsNCT06481891
Recruiting

Retrospective Natural History Study of RASopathy-associated Cardiomyopathy (RAS-CM)

Heart FailureHypertrophic Cardiomyopathy (HCM)RASopathy
Deutsches Herzzentrum Muenchen100 enrolled1 locationNCT07344480
Recruiting

Study of the Progression of Chronic Cardiovascular Conditions

Heart FailureHypertensionDilated Cardiomyopathy+9 more
Prolaio5,000 enrolled1 locationNCT07420907
Recruiting
Early Phase 1

Sodium Glucose Co-transporter (SGLT) Inhibitors in Nonobstructive Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy Without Obstruction
University of Pennsylvania26 enrolled1 locationNCT06433050
Recruiting
Phase 2

A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

Non-obstructive Hypertrophic Cardiomyopathy
Imbria Pharmaceuticals, Inc.165 enrolled23 locationsNCT07023614
Recruiting

Myocardial Perfusion CMR for Differentiating and Characterizing Hypertrophic Cardiomyopathy Phenotypes

Anderson Fabry DiseaseAmyloid CardiomyopathyCardiac Magnetic Resonance Imaging+1 more
IRCCS Azienda Ospedaliero-Universitaria di Bologna250 enrolled1 locationNCT07382128
Recruiting

Mavacamten Post-marketing Surveillance in Patients With Obstructive Hypertrophic Cardiomyopathy in Japan

Obstructive Hypertrophic Cardiomyopathy (oHCM)
Bristol-Myers Squibb200 enrolled1 locationNCT07383025
Recruiting
Not Applicable

Left Bundle Branch Pacing in Patients With Hypertrophic Cardiomyopathy After Myectomy

Sudden Cardiac DeathHeart Failure (HF)HCM - Hypertrophic Cardiomyopathy+2 more
Meshalkin Research Institute of Pathology of Circulation30 enrolled1 locationNCT07372196
Recruiting

Multimodal Analysis of Endomyocardial Biopsies

CardiomyopathiesHypertrophic Cardiomyopathy (HCM)Heart Transplantation+4 more
University Hospital, Essen216 enrolled1 locationNCT07359690
Recruiting

Institutional Registry of Rare Diseases

ParagangliomaPheochromocytomaAmyloidosis+23 more
Hospital Italiano de Buenos Aires380 enrolled1 locationNCT06573723
Recruiting

The Application of T1 Mapping in Real-World

Hypertrophic Cardiomyopathy (HCM)MyocarditisMyocardial Infarction (MI)+2 more
Chinese Academy of Medical Sciences, Fuwai Hospital2,000 enrolled1 locationNCT07354646
Recruiting

National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry

Sudden Cardiac DeathArrhythmogenic Right Ventricular DysplasiaCardiomyopathy, Dilated+11 more
Hospital do Coracao600 enrolled27 locationsNCT06546137
Recruiting
Not Applicable

Mavacamten Enables Exercise in Hypertrophic Obstructive Cardiomyopathy

Cardiomyopathy, Hypertrophic
Technical University of Munich24 enrolled1 locationNCT07077005