Phase 1 Infections Clinical Trials
47 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 47 trials
Recruiting
Phase 1Phase 2
A Phase I Study of Mozobil in the Treatment of Patients With WHIMS
NeutropeniaInfectionsWarts+2 more
National Institute of Allergy and Infectious Diseases (NIAID)20 enrolled1 locationNCT00967785
Recruiting
Phase 1
Safety and Pharmacokinetics of Ingavirin Forte, Capsules, 90 mg + 20 mg (Valenta Pharm JSC, Russia) Compared With Ingavirin, Capsules, 90 mg, Under Fasting and Fed Conditions.
InfluenzaAcute Respiratory Viral Infections
Valenta Pharm JSC36 enrolled1 locationNCT07645534
Recruiting
Phase 1
R-MVST Cells for Treatment of Viral Infections
Epstein-Barr Virus InfectionsCytomegalovirus InfectionsBK Virus Infection+1 more
Columbia University36 enrolled1 locationNCT05183490
Recruiting
Phase 1Phase 2
Study on Safety and Efficacy of Two Doses of PRS CK STORM in the Modulation of the Cytokine Storm in Patients With Acute Respiratory Infection Caused by SARS-Cov-2, Influenza A, Influenza B and Respiratory Syncytial Virus (RSV)
Systemic Inflammatory Response SyndromeSARS CoV-2Respiratory distress syndrome+2 more
PEACHES BIOTECH50 enrolled3 locationsNCT06684379
Recruiting
Phase 1
Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)40 enrolled9 locationsNCT06665646
Recruiting
Phase 1
Dasatinib for HIV-1 Reservoir Reduction
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)14 enrolled3 locationsNCT07342491
Recruiting
Phase 1Phase 2
A Study of BLB-201 RSV Vaccine in Infants and Children
Respiratory Syncytial Virus Infections
Blue Lake Biotechnology Inc.137 enrolled15 locationsNCT05655182
Recruiting
Phase 1Phase 2
The Tatelo Plus Study
HIV InfectionsHIV
National Institute of Allergy and Infectious Diseases (NIAID)41 enrolled2 locationsNCT06508749
Recruiting
Phase 1Phase 2
Clinical Trial of Recombinant RSV Vaccine (CHO Cell) (Adjuvanted) in Chinese Population Aged 18 Years and Older.
Respiratory Syncytial Virus Infections
Ab&B Bio-tech Co., Ltd.JS470 enrolled1 locationNCT07582796
Recruiting
Phase 1Phase 2
A Study to Investigate Cabotegravir for Neonates Exposed to HIV-1
HIV Infections
ViiV Healthcare44 enrolled1 locationNCT07275606
Recruiting
Phase 1
Safety and Immunogenicity Study of Three mRNAs Encoding HIV Immunogens in Adult Participants Without HIV and in Overall Good Health in South Africa.
HIV Infections
International AIDS Vaccine Initiative96 enrolled6 locationsNCT06694753
Recruiting
Phase 1
A Study of How Ibuzatrelvir is Taken up Into the Blood of Healthy Adults After Taking Different Tablets of Ibuzatrelvir
Upper respiratory tract infectionsrespiratory tract infectionCOVID-19 (SARS-CoV-2) infection+8 more
Pfizer18 enrolled1 locationNCT07552779
Recruiting
Phase 1Phase 2
A Study on the Safety and Immune Response of a Urinary Tract Infection (UTI) Vaccine in Adults 18-64 Years of Age and Clinical Efficacy in Females 18-64 Years of Age
Urinary Tract Infections
GlaxoSmithKline448 enrolled8 locationsNCT06702449
Recruiting
Phase 1
First Time in Human Study of Long Acting VH4524184 Formulations
HIV Infections
ViiV Healthcare268 enrolled3 locationsNCT06310551
Recruiting
Phase 1Phase 2
CAR-T Cells for HIV Infection
HIV Infections
Steven Deeks18 enrolled2 locationsNCT04648046
Recruiting
Phase 1Phase 2
FMT for the Decolonization of Carbapenem-resistant Enterobacteriaceae
Enterobacteriaceae InfectionsMulti-antibiotic Resistance
Fondazione Policlinico Universitario Agostino Gemelli IRCCS52 enrolled1 locationNCT04759001
Recruiting
Phase 1
[18F]Fluoropropyl-Trimethoprim ([18F]F-TMP) PET/CT Imaging to Evaluate Biodistribution and Kinetics in Human Subjects
Bacterial Infections
University of Pennsylvania20 enrolled1 locationNCT04263792
Recruiting
Phase 1
Single-Dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Pevifoscorvir Sodium (ALG-000184) in Subjects With Moderate Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function
Chronic Hepaititis B Infections
Aligos Therapeutics16 enrolled1 locationNCT07342868
Recruiting
Phase 1Phase 2
A Double-Blind, Active-Controlled, Multiple-Ascending Dose Study of Aerosolized RSP-1502 in Subjects With CF and Chronic PA Lung Infection
Pseudomonas aeruginosaCystic Fibrosis LungRespiratory Infections, Recurrent, Chronic
Respirion Pharmaceuticals Pty Ltd72 enrolled22 locationsNCT06016088
Recruiting
Phase 1
A Study to Investigate the Use of VH3810109 With or Without Fostemsavir (FTR) to Reduce the Size and Activity of the Viral Reservoir in People Living With HIV
HIV Infections
ViiV Healthcare100 enrolled41 locationsNCT07053384