Phase 3 Infections Clinical Trials
49 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 49 trials
Recruiting
Phase 3
PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation
InfectionsInjury LegAmputation+6 more
Major Extremity Trauma Research Consortium250 enrolled13 locationsNCT05699174
Recruiting
Phase 3
Letermovir (Prevymis) for CMV in Kidney and Pancreas Transplant Recipients
Cytomegalovirus InfectionsKidney Transplant InfectionPancreas Transplant
University of Wisconsin, Madison90 enrolled1 locationNCT06407232
Recruiting
Phase 3
STI Testing to Enhance PrEP Use in Pregnancy
PregnancySexually Transmitted Infections (STIs)PrEP Adherence
Botswana Harvard AIDS Institute Partnership600 enrolled1 locationNCT06919614
Recruiting
Phase 3
VE303 for Prevention of Recurrent Clostridioides Difficile Infection
Clostridium Difficile Infection RecurrenceClostridium DifficileClostridioides Difficile Infection+7 more
Vedanta Biosciences, Inc.852 enrolled215 locationsNCT06237452
Recruiting
Phase 3
A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1
HIV Infections
ViiV Healthcare332 enrolled89 locationsNCT06694805
Recruiting
Phase 3
A Study on the Immune Response and Safety of Vaccine Against Respiratory Syncytial Virus Given to Chinese Adults 18 to 59 Years of Age at Increased Risk of Respiratory Syncytial Virus Disease
Respiratory Syncytial Virus Infections
GlaxoSmithKline750 enrolled15 locationsNCT07220109
Recruiting
Phase 3
A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Infections.
Invasive Mold Infections
Basilea Pharmaceutica234 enrolled52 locationsNCT06925321
Recruiting
Phase 3
Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)
Central Line Associated Blood Stream Infections (CLABSI)
CorMedix200 enrolled22 locationsNCT06822426
Recruiting
Phase 3
A Clinical Trial on Safety in Pregnant Women and How Well the Infant is Protected Against RSV-associated Lower Respiratory Tract Infection When the Pregnant Woman Receives the Approved RSV Vaccine Compared to a Placebo.
preterm labourRSV ImmunisationRSV Infections
University of Witwatersrand, South Africa13,000 enrolled11 locationsNCT06955728
Recruiting
Phase 3
Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID
SARS-CoV-2 infectionCOVID-19Long COVID+1 more
Wes Ely550 enrolled17 locationsNCT06631287
Recruiting
Phase 3
Effect of Bismuth Add-on to Dual Therapy for Helicobacter Pylori Eradication
Helicobacter Pylori Infections
National Taiwan University Hospital990 enrolled1 locationNCT07576959
Recruiting
Phase 3
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
Adenovirus Infections
SymBio Pharmaceuticals180 enrolled61 locationsNCT07387367
Recruiting
Phase 3
A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma
Non-Hodgkin LymphomaBacterial InfectionsHypogammaglobulinemia+2 more
Grifols Therapeutics LLC386 enrolled62 locationsNCT05645107
Recruiting
Phase 3
Light-Activated Antimicrobial Therapy to Prevent Surgical Site Infections
Surgical Site Infections
Ondine Biomedical Inc.4,514 enrolled14 locationsNCT06702878
Recruiting
Phase 3
A Study to Evaluate the Immunogenicity and Safety of 13-valent Pneumococcal Conjugate Vaccine (PCV13i) in Healthy Infants Aged 2 Months (Minimum 6 Weeks)
Bacterial InfectionsPneumococcal InfectionsStreptococcal Infections
CanSino Biologics Inc.600 enrolled3 locationsNCT07017777
Recruiting
Phase 3
Low Dose Trimethoprim-Sulfamethoxazole for the Treatment of Pneumocystis Jirovecii Pneumonia
Pneumocystis PneumoniaPneumocystisPneumocystis Jirovecii Infection+5 more
Todd C. Lee MD MPH FIDSA416 enrolled1 locationNCT04851015
Recruiting
Phase 3
Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children
Respiratory Syncytial Virus Infections
University of Alabama at Birmingham370 enrolled15 locationsNCT05026749
Recruiting
Phase 2Phase 3
A Follow-up Trial of GBS-NN/NN2 Vaccine in Healthy Pregnant Women
Neonatal SepsisPneumoniaInfections+6 more
Minervax ApS338 enrolled6 locationsNCT06592586
Recruiting
Phase 3
Assessment of Immunogenicity, Reactogenicity and Safety of the Drug GNG-DE in Comparison With the Reference Drug
InfectionsMeningococcal
NPO Petrovax240 enrolled17 locationsNCT06834100
Recruiting
Phase 3
Long-term Follow-up of Long-acting Cabotegravir (CAB LA) for PrEP (Pre-exposure Prophylaxis) in Participants at Risk of Acquiring HIV (Human Immunodeficiency Virus)
HIV Infections
ViiV Healthcare3,508 enrolled34 locationsNCT06134362