Phase 1 Inflammatory Bowel Disease Clinical Trials
16 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–16 of 16 trials
Recruiting
Phase 1
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmRheumatoid Arthritis+11 more
National Cancer Institute (NCI)300 enrolled52 locationsNCT03816345
Recruiting
Phase 1
A Phase 1 Study of PVT401 in Healthy Subjects
Inflammatory Bowel Disease (IBD)
Parvus Therapeutics, Inc.36 enrolled1 locationNCT07423000
Recruiting
Phase 1
A Phase I Study of HW201877 in Healthy Subjects
Healthy ParticipantsIBD (Inflammatory Bowel Disease)
Wuhan Humanwell Innovative Drug Research and Development Center Limited Company104 enrolled1 locationNCT07373457
Recruiting
Phase 1Phase 2
Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-TNF Therapy
Inflammatory Bowel DiseasesCrohn DiseaseUlcerative Colitis
Children's Hospital Medical Center, Cincinnati116 enrolled3 locationsNCT03847467
Recruiting
Phase 1
Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for IBD
Inflammatory Bowel Diseases
The Foundation for Orthopaedics and Regenerative Medicine15 enrolled2 locationsNCT05003947
Recruiting
Phase 1Phase 2
Microbial Restoration in Inflammatory Bowel Diseases
Inflammatory Bowel DiseasesCrohn DiseaseMicrobiome+1 more
St Vincent's Hospital Melbourne120 enrolled1 locationNCT04970446
Not Yet Recruiting
Phase 1
The Pharmacokinetics and the Effect of Extended-release Thioguanine Tablets on Symptoms in Adults with Ulcerative Colitis.
Inflammatory Bowel DiseaseActive Ulcerative Colitis
Douglas Pharmaceuticals12 enrolled1 locationACTRN12624001448538
Recruiting
Phase 1
Phase 1 Study for IPG11406 in Health Volunteer
Inflammatory Bowel Diseases
Nanjing Immunophage Biotech Co., Ltd66 enrolled1 locationNCT06255834
Recruiting
Phase 1Phase 2
Beta-Hydroxybutyrate Feasibility Treating IBD
Inflammatory Bowel DiseasesCrohn's Disease
University of Texas at Austin20 enrolled1 locationNCT06351124
Active
Phase 1
A Study to Evaluate the Effects of Food on Pharmacokinetics of AC-101
Inflammatory Bowel Disease
Accro Bioscience (Australia) Pty Ltd12 enrolled1 locationACTRN12623000243617
Active
Phase 1
Part 1 and Part 3: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics of AC-101
Inflammatory Bowel Disease
Accro Bioscience (Australia) Pty Ltd70 enrolled1 locationACTRN12623000234617
Withdrawn
Phase 1
Comparative bioavailability assessment between 2 x 10 mg R-178 tablets and 2 x 10 mg 2-amino-1,7-dihydro-6H-purine-6-thione tablets administered orally in healthy participants under fasting conditions.
2-amino-1,7-dihydro-6H-purine-6-thione is indicated for the maintenance treatment of inflammatory bowel disease (Crohn's disease or ulcerative colitis).
Zenith Technology Corporation Limited14 enrolled1 locationACTRN12622000579796
Completed
Phase 1
A Phase I Clinical Trial to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Single- and Multiple-Ascending Doses of RS1805 Tablets in Healthy Adult Subjects
Inflammatory Bowel Disease
Atridia Pty Ltd88 enrolled2 locationsACTRN12620000910909
Recruiting
Phase 1
A Randomized, Placebo-Controlled, Sequential Single and Multiple Dose-Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Oral BT-11 in Healthy Adult Male and Female Volunteers
Crohn's DiseaseInflammatory Bowel Disease
Landos Biopharma Australia Pty Ltd70 enrolled1 locationACTRN12618001210268
Completed
Phase 1
Relative Bioavailability and Effect of Food and Esomeprazole on the Pharmacokinetics of PRN1008 in Healthy Volunteers.
Rheumatoid ArthritisInflammatory Bowel DiseaseSystemic Lupus Erythematosus
Clinical Network Services Pty Ltd12 enrolled1 locationACTRN12615000936527
Completed
Phase 1
A Phase 1, Single-Center, Open-label Study to Evaluate the Pharmacokinetics of PRN1008 in Healthy Male and Female Volunteers
Rheumatoid ArthritisInflammatory Bowel DiseaseSystemic Lupus Erythematosus
Clinical Network Services (CNS) Pty Ltd12 enrolled1 locationACTRN12615000614594