Early Phase 1 IOP Clinical Trials
13 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–13 of 13 trials
Recruiting
Early Phase 1
MTS109 in Patients With Refractory Autoimmune Diseases
Systemic Lupus ErythematosusIdiopathic Inflammatory MyopathiesSystemic Sclerosis (SSc)
Shanghai Changzheng Hospital15 enrolled1 locationNCT07526350
Recruiting
Early Phase 1
A Study of CC312 for Relapsed/Refractory Autoimmune Diseases
SLE - Systemic Lupus ErythematosusSSc-Systemic SclerosisIIM- Idiopathic Inflammatory Myopathies
CytoCares Inc6 enrolled1 locationNCT07193810
Recruiting
Early Phase 1
A Clinical Study to Evaluate Safety, Tolerability and Pharmacokinetics of SV001 in Chinese Healthy Adult Volunteers.
Idiopathic Pulmonary Fibrosis
Shanghai Synvida Biotechnology Co.,Ltd.53 enrolled1 locationNCT06267183
Recruiting
Early Phase 1
Efficacy and Safety of Pozelimab and Cemdisiran Combination Therapy in Patients With Sporadic Inclusion Body Myositis
Idiopathic Inflammatory MyopathiesSporadic Inclusion Body Myositis (sIBM)
Austin Neuromuscular Center10 enrolled2 locationsNCT06479863
Recruiting
Early Phase 1
GC012F Injection in Refractory Idiopathic Inflammatory Myopathy
Idiopathic Inflammatory Myopathy (IIM)
Daishi Tian12 enrolled1 locationNCT07086404
Recruiting
Early Phase 1
the Safety and Efficacy of Targeted BCMA In Vivo LV Injection for Recurrent or Refractory Autoimmune Diseases
Recurrent or Refractory Systemic Lupus ErythematosusRecurrent or Refractory IgG4 Related DiseasesRecurrent or Refractory Systemic Sclerosis+2 more
Tongji Hospital45 enrolled1 locationNCT07339540
Recruiting
Early Phase 1
An Exploratory Study of CD19/CD22/BCMA CAR-T Cells (BZE2204) in Subjects With Relapsed or Refractory Autoimmune Diseases
Idiopathic Inflammatory Myopathies(IIM)
Shanghai Cell Therapy Group Co.,Ltd20 enrolled1 locationNCT07174843
Recruiting
Early Phase 1
Safety Study of CC312 in Autoimmune Disease Patients
Rheumatoid Arthritis (RA)Autoimmune Hemolytic AnemiaSystemic Lupus Erythematosus (SLE)+3 more
CytoCares Inc18 enrolled1 locationNCT06888960
Recruiting
Early Phase 1
Hyperpolarized Xenon-129 MRI in Idiopathic Pulmonary Fibrosis
Idiopathic Pulmonary Fibrosis
University of Virginia6 enrolled1 locationNCT06853145
Recruiting
Early Phase 1
FAPI PET for Lung Fibrosis
PneumoconiosisRadiation PneumonitisInterstitial Lung Disease+4 more
University of California, Los Angeles30 enrolled1 locationNCT05365802
Recruiting
Early Phase 1
Safety and Efficacy of CT103A Cells for Relapsed/Refractory Antibody-associated Inflammatory Diseases of the Nervous System
Myasthenia GravisAutoimmune EncephalitisMultiple Sclerosis+7 more
Tongji Hospital36 enrolled1 locationNCT04561557
Recruiting
Early Phase 1
Inhaled Nitric Oxide (iNO) in Idiopathic Pulmonary Fibrosis (IPF).
Idiopathic Pulmonary Fibrosis
Dr. Denis O'Donnell40 enrolled1 locationNCT05052229
Completed
Early Phase 1
A Single Microdose Study to Evaluate the Pharmacokinetics of INS018_055 in Healthy Participants
Idiopathic Pulmonary Fibrosis (IPF)
Insilico Medicine Hong Kong Limited8 enrolled1 locationACTRN12621001541897