IOP Clinical Trials

1 recruiting

Frequently Asked Questions

Common questions about IOP clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 161 trials

Recruiting
Phase 2

Safety, Tolerability and Symptomatic Efficacy of the ROCK-Inhibitor Fasudil in Patients With Parkinson's Disease

Idiopathic Parkinson´s Disease
Technical University of Munich75 enrolled1 locationNCT05931575
Recruiting
Phase 1

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.

Rheumatoid ArthritisSystemic Lupus ErythematosusIdiopathic Inflammatory Myopathies
AstraZeneca72 enrolled33 locationsNCT06916806
Recruiting
Phase 2

Urinary Tumor DNA-Guided Systemic Immunotherapy for Unresectable Very-High-Risk Non-Muscle-Invasive Bladder Cancer

Bladder CancerImmunotherapyLiquid Biopsy
Tianjin Medical University Second Hospital53 enrolled1 locationNCT07475403
Recruiting
Not Applicable

Performance of the Cardiac Microcurrent (C-MIC) System With a Less Invasively Placed Left Ventricular Lead

Non-ischemic CardiomyopathyLeft Ventricular (LV) Systolic DysfunctionIdiopathic Cardiomyopathy
Berlin Heals GmbH22 enrolled4 locationsNCT06920030
Recruiting
Not Applicable

Guiding Value of Urinary Tumor DNA Testing in Cystoscopy for High-Risk/Very High-Risk Non-Muscle-Invasive Bladder Cancer

Bladder CancerLiquid BiopsyCystoscopy
Tianjin Medical University Second Hospital360 enrolled2 locationsNCT07180212
Recruiting

Natural History of Noncirrhotic Portal Hypertension

Cystic FibrosisTurner SyndromeImmunologic Deficiency Syndrome+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)400 enrolled1 locationNCT02417740
Recruiting
Phase 3

Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders

Turner SyndromeIdiopathic Short StatureShort Stature Homeobox Gene Mutation+1 more
Ascendis Pharma A/S186 enrolled4 locationsNCT07221851
Recruiting
Not Applicable

Open-label Placebo (COLP) for Pain in Adolescent Idiopathic Scoliosis (AIS) Surgery+Surgical Treatment of Idiopathic Scoliosis

Adolescent Idiopathic Scoliosis (AIS)
University of California, San Francisco64 enrolled1 locationNCT06365892
Recruiting

Risk and Resilience in Pulmonary Arterial Hypertension and Genetically Susceptible Individuals

Idiopathic Pulmonary Arterial HypertensionHeritable Pulmonary Arterial HypertensionUnaffected Mutation Carriers: Healthy Participants With a Known BMPR2 Gene Mutation and Normal Pulmonary Pressure and RV Function on Echo+1 more
Vanderbilt University Medical Center150 enrolled1 locationNCT05584722
Recruiting

The Investigation of Kinesiophobia in Conservative Distal Radius Fractures

Distal Radius FractureKinesiophobiaFunctional Status
Pamukkale University34 enrolled2 locationsNCT07291505
Recruiting

Etiology-Phenotype-Outcome Pathway Study on Freezing of Gait (FOG)

Parkinson's DiseaseParkinsonismFreezing of Gait+2 more
Tianjin Huanhu Hospital700 enrolled1 locationNCT07386015
Recruiting

Clinical Validation of Early Detection Blood Test for Universal Large-scale Breast Cancer Screening

Breast Cancer, Liquid Biopsy, Early Detection
Syantra Inc.2,000 enrolled4 locationsNCT07219277
Recruiting
Not Applicable

Venous Stenting Evaluation in Patients With Intracranial Hypertension Under Long-term Acetazolamide

Idiopathic Intracranial Hypertension (IIH)
University Hospital, Montpellier114 enrolled3 locationsNCT06945848
Recruiting
Not Applicable

Effect of Intrarectal Ice Application on Pain, Anxiety, Cortisol Levels, Development of Complications, and Hospital Readmission in Transrectal Ultrasound-Guided Prostate Biopsy

TRANSRECTAL ULTRASOUND-GUIDED PROSTATE BIOPSY
Tarsus University84 enrolled2 locationsNCT07462390
Recruiting
Early Phase 1

Clinical Study on Targeted CD19 or CD19-BCMA CAR-T Therapy for Autoimmune Diseases

Sjogren's SyndromeAutoimmune DiseasesIdiopathic Inflammatory Myopathies+3 more
Nanjing Bioheng Biotech Co., Ltd.20 enrolled1 locationNCT06548607
Recruiting
Phase 2

Effect of Perioperative Lidocaine or High-Dose Dexamethasone on Immune Response in Colon Cancer Surgery (PILDI Study)

Colorectal, CancerColon CancerPerioperative Immune Response
Institute of Oncology Ljubljana100 enrolled1 locationNCT07432399
Recruiting

The Guiding Value of Liquid Biopsy Based on Urinary Tumor DNA/RNA in the Second Transurethral Resection of High-risk Non-muscle Invasive Bladder Cancer

Bladder CancerLiquid Biopsy
Tianjin Medical University Second Hospital60 enrolled2 locationsNCT07130578
Recruiting

Using Liquid Biopsy Testing to Identify, Monitor, Predict Recurrence in Urothelial Carcinoma

Urothelial Carcinoma (UC)Bladder (Urothelial, Transitional Cell) CancerLiquid Biopsy
Tianjin Medical University Second Hospital300 enrolled1 locationNCT07441499
Recruiting
Not Applicable

Guiding Value of Urinary Tumor DNA Testing in Repeat Transurethral Resection of Non-Muscle-Invasive Bladder Cancer

Bladder CancerLiquid BiopsyRepeat Transurethral Resection of Bladder Tumor
Tianjin Medical University Second Hospital196 enrolled2 locationsNCT07187635
Recruiting
Not Applicable

IIH Intervention: A Clinical Trial Comparing 2 Treatments (Shunts and Stents) Evaluation Of Clinical Effectiveness And Cost Effectiveness

IIH - Idiopathic Intracranial Hypertension
University of Birmingham80 enrolled15 locationsNCT07440277