Joint Disease Clinical Trials

2 recruiting

Joint Disease Trials at a Glance

31 actively recruiting trials for joint disease are listed on ClinicalTrialsFinder across 6 cities in 28 countries. The largest study group is Not Applicable with 13 trials, with the heaviest enrollment activity in Miami, Salt Lake City, and Cleveland. Lead sponsors running joint disease studies include Aesculap AG, Zimmer Biomet, and Dedienne Sante S.A.S..

Browse joint disease trials by phase

Treatments under study

About Joint Disease Clinical Trials

Looking for clinical trials for Joint Disease? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Joint Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Joint Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 31 trials

Recruiting

Oxidative Stress in Autoimmune Rheumatic Diseases

Psoriatic Arthritis (PsA)Ankylosing Spondylitis (AS)Rheumatoid Arthritis (RA)+1 more
University of Thessaly200 enrolled1 locationNCT07536529
Recruiting
Phase 2

A Study of SPY072 in Rheumatic Disease

Rheumatoid ArthritisPsoriatic ArthritisRheumatic Diseases+5 more
Spyre Therapeutics, Inc.285 enrolled57 locationsNCT07148414
Recruiting
Not Applicable

Patient Outcomes Following Kinematic and Functional Alignment in Robotic-Assisted Total Knee Arthroplasty With Randomized Insert Types

Knee OsteoarthritisDegenerative Joint Disease of the Knee
Singapore General Hospital240 enrolled1 locationNCT07533188
Recruiting

Comparative Study of Navigation-assisted OrthoPilot® Elite and Robotic-assisted MAKO® Total Knee Arthroplasty

Osteoarthritis, KneePosttraumatic ArthropathyJoint Diseases+1 more
Aesculap AG140 enrolled1 locationNCT05980442
Recruiting

Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry

Musculoskeletal DiseasesOsteoarthritisJoint Diseases+3 more
Xiaojuan Li88 enrolled1 locationNCT04536103
Recruiting
Not Applicable

Long-Term Study of CartiPRO for Knee Pain Due to Osteoarthritis or Cartilage Damage

Knee OsteoarthritisOsteoarthritisDegenerative Joint Disease of Knee+2 more
DALIM TISSEN Co., Ltd.194 enrolled5 locationsNCT07267793
Recruiting

Zimmer Biomet Shoulder Arthroplasty PMCF Study

Degenerative Joint DiseaseShoulder PainShoulder Fractures+3 more
Zimmer Biomet40 enrolled2 locationsNCT06920459
Recruiting
Not Applicable

Safety and Effectiveness of the HIT Reverse HRS

Degenerative Joint DiseaseOsteoarthritis, HipAvascular Necrosis of Hip+1 more
Hip Innovation Technology288 enrolled6 locationsNCT05357378
Recruiting

Study to Evaluate the Performance of Navigated TKA With OrthoPilot® pheno4u TKA Level 1

Osteoarthritis, KneePosttraumatic ArthropathyJoint Diseases+1 more
Aesculap AG120 enrolled4 locationsNCT06955481
Recruiting

Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

Rheumatic Joint Disease
Duke University20,000 enrolled82 locationsNCT02418442
Recruiting
Not Applicable

Genicular Artery Embolization Vs Observation for Symptomatic Knee Osteoarthritis

Knee OsteoarthritisDegenerative Joint Disease of Knee
University of California, Los Angeles100 enrolled1 locationNCT04682652
Recruiting

Evaluating the Safety and Efficacy of the ROMAX Resurfacing System in patients undergoing hip resurfacing.

Congenital or Developmental disordersHip ResurfacingDegenerative Joint Disease
Medacta Australia Pty Ltd280 enrolled1 locationACTRN12625000948493
Recruiting
Not Applicable

Cryoneurolysis of the Suprascapular Nerve for Perioperative Pain Control After Receiving a Reverse Total Shoulder Arthroplasty (RTSA)

Degenerative Joint Disease of Shoulder
North Texas Medical Research Institute, PLLC20 enrolled1 locationNCT07125833
Recruiting
Not Applicable

G7 Acetabular System With Vivacit-E or Longevity Liner PMCF Study

Osteoarthritis, HipTotal Hip ArthroplastyDegenerative Joint Disease of Hip+5 more
Zimmer Biomet300 enrolled11 locationsNCT04754087
Recruiting
Not Applicable

A Prospective, Pre-market, Multi-center Study of Insignia Hip Stem in THA to Determine Implant Survivorship and PROMS.

Arthritis (E.G., Degenerative Joint Disease (DJD), Osteoarthritis, and Rheumatoid Arthritis (RA))
Stryker Australia Pty Ltd.313 enrolled1 locationNCT06108934
Recruiting

The Application of Artificial Intelligence in Wrist and Hand Joint Ultrasound

Joint DiseasesEducation
West China Hospital500 enrolled1 locationNCT06883669
Recruiting

Extracellular Vesicles in Fibrin Gel for Cartilage Repair

Joint Disease
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio51 enrolled1 locationNCT06713902
Recruiting
Not Applicable

Evaluating Replacement of Standard-of-care Low Dose Computer Tomography (CT) Scans With Radiation-free Bone Imaging by Deep-learning Augmented Zero Echo Time (DL-ZTE) Magnetic Resonance Tomography (MRT)

Joint DiseasesJoint Inflammation
Roman Guggenberger100 enrolled1 locationNCT06579547
Recruiting

Safety and Performance Assessment of the SYMBOL Range of Medical Devices in Patients Underlying Total Hip Arthroplasty

Avascular Necrosis of the Femoral HeadPost-traumatic OsteoarthritisHip Arthritis+3 more
Dedienne Sante S.A.S.747 enrolled9 locationsNCT05227924
Recruiting
Not Applicable

Hyaluronic Acid and Adelmidrol (Hyadrol®) in Patients With Degenerative Joint Disease

Degenerative Joint Disease
University of Roma La Sapienza59 enrolled1 locationNCT06506656