Joint Infection Clinical Trials

3 recruiting

Joint Infection Trials at a Glance

19 actively recruiting trials for joint infection are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in New York, Los Angeles, and Boston. Lead sponsors running joint infection studies include First Affiliated Hospital of Fujian Medical University, Centre Hospitalier Universitaire, Amiens, and Akiva Mintz.

Browse joint infection trials by phase

Treatments under study

About Joint Infection Clinical Trials

Looking for clinical trials for Joint Infection? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Joint Infection trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Joint Infection clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 119 of 19 trials

Recruiting
Phase 2

Study to Evaluate the REMEDY SPECTRUM IM Spacer Nail in the Treatment of Ankle-Related Infections

Periprosthetic Joint Infection
OsteoRemedies, LLC60 enrolled3 locationsNCT06428448
Recruiting
Phase 1Phase 2

A Phase 1/2 Study to Evaluate the Safety, PK and Efficacy of TNP-2092 Administered Via IA Injection in PJI Participants

Periprosthetic Joint Infection (PJI)
TenNor Therapeutics Inc.33 enrolled1 locationNCT06889701
Recruiting
Not Applicable

IP-coated Revision Hip Implants

Peri-Prosthetic Joint Infection
Aesculap AG268 enrolled2 locationsNCT06737809
Recruiting
Not Applicable

Rifampin-combined Antibiotic Therapy for Staphylococcal PJI

Periprosthetic Joint Infection
First Affiliated Hospital of Fujian Medical University428 enrolled1 locationNCT07313215
Recruiting
Phase 2

Ultralow Dose PET Imaging for 18F-NaF Uptake

Healthy VolunteerArthritisBone and Joint Infection+2 more
Akiva Mintz200 enrolled2 locationsNCT07284563
Recruiting
Phase 4

The Use of CCK vs PS in Revision TKAs

Aseptic Loosening of Prosthetic JointInstability of Prosthetic JointReimplantation for Periprosthetic Joint Infection+2 more
Rush University Medical Center170 enrolled1 locationNCT06782295
Recruiting
Phase 2

Study to Evaluate the Efficacy and Safety of TRL1068 for the Treatment of Prosthetic Joint Infection

Prosthetic Joint Infections of HipProsthetic Joint Infections of Knee
Trellis Bioscience LLC60 enrolled17 locationsNCT06621251
Recruiting

A Diagnostic Test Accuracy Study Comparing Biopsy to Aspiration in Shoulder and Elbow Arthroplasty Revision Surgery (BASE Study)

Periprosthetic Joint Infection
Wrightington, Wigan and Leigh NHS Foundation Trust244 enrolled1 locationNCT06268795
Recruiting
Not Applicable

Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis

Joint InfectionInfection of Hip Joint (Disorder)Infection of Shoulder Joint
Hospital for Special Surgery, New York442 enrolled3 locationsNCT03704766
Recruiting
Not Applicable

Ofloxacin Concentration-toxicity Relationship in the Elderly

Therapeutic Drug MonitoringBone and Joint InfectionOfloxacin
Centre Hospitalier Universitaire, Amiens110 enrolled1 locationNCT04496024
Recruiting
Not Applicable

Rate of Total Joint Infection 90-day After Surgery Following Irrigation With Next Science No-Rinse Solution vs SOC Alone

Joint Infection
Northwell Health936 enrolled3 locationsNCT05519007
Recruiting

Molecular Biology in the Identification of Pathogens at Reimplantation in the Two-Stage Treatment of Periprosthetic Infections

Periprosthetic Joint Infection (PJI)
IRCCS Azienda Ospedaliero-Universitaria di Bologna100 enrolled1 locationNCT06804265
Recruiting
Not Applicable

Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth In/near Infected Bone Cavities

Periprosthetic Joint Infections
Elute, Inc.204 enrolled12 locationsNCT05361941
Recruiting

Side Effects of Antibiotics in Bone and Joint Infections

Bone InfectionJoint Infection
University Hospital, Tours300 enrolled1 locationNCT05927311
Recruiting
Not Applicable

Optimizing Infection Prophylaxis Prior to Shoulder Surgery

Arthroplasty ShoulderPeriprosthetic Joint Infection
University of Washington40 enrolled1 locationNCT06464770
Recruiting
Phase 3

Infection Prophylaxis in Total Joint Replacement

Periprosthetic Joint Infection
Hamilton Health Sciences Corporation21,006 enrolled1 locationNCT06126614
Recruiting

Bacterial evolution during golden staph infections

Bone and joint infectionsStaphylococcus aureus infectionsSepsis
University of Melbourne200 enrolled2 locationsACTRN12623001222639
Recruiting

Phage Safety Retrospective Cohort Study

Bone and Joint Infection
Hospices Civils de Lyon25 enrolled1 locationNCT04724603
Recruiting

Prospective Cohort Study on Antibiotic Course and Efficacy After Two-stage Revision in PJI.

Anti-Bacterial AgentsPeriprosthetic Joint Infection
First Affiliated Hospital of Fujian Medical University500 enrolled1 locationNCT05284318