Keratitis Clinical Trials

19 recruitingLast updated: May 11, 2026

There are 19 actively recruiting keratitis clinical trials across 10 countries. Studies span Phase 2, Phase 1, Phase 3, Phase 4, Early Phase 1, Not Applicable. Top locations include San Francisco, California, United States, Carmel, Indiana, United States, Pittsburgh, Pennsylvania, United States. Updated daily from ClinicalTrials.gov.


Keratitis Trials at a Glance

19 actively recruiting trials for keratitis are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Phase 2 with 6 trials, with the heaviest enrollment activity in San Francisco, Carmel, and Pittsburgh. Lead sponsors running keratitis studies include BRIM Biotechnology Inc., CHU de Reims, and Assistance Publique - Hôpitaux de Paris.

Browse keratitis trials by phase

Treatments under study

About Keratitis Clinical Trials

Looking for clinical trials for Keratitis? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Keratitis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Keratitis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 119 of 19 trials

Recruiting
Phase 2

A Multicenter, Randomized, Vehicle-Controlled, Double-Masked to Open-Label Study to Evaluate the Safety and Efficacy of Lacripep 4 μM Ophthalmic Solution in Subjects With Neurotrophic Keratitis

Neurotrophic Keratitis
TearSolutions, Inc.54 enrolled3 locationsNCT07568730
Recruiting
Phase 3

Parasitic Ulcer Treatment Trial

Acanthamoeba keratitis
Jeremy Keenan, MD, MPH232 enrolled17 locationsNCT06213649
Recruiting
Phase 2

A Phase II Study of STSP-0902 Ophthalmic Solution in Patients With Neurotrophic Keratitis

Neurotrophic Keratitis
Staidson (Beijing) Biopharmaceuticals Co., Ltd48 enrolled1 locationNCT06975748
Recruiting

Retrospective Chart Review of Patients With Acanthamoeba Keratitis Who Have Received 0.8 mg/mL Polihexanide as Part of the "Medicines in Special Situations" (Medicamentos en Situaciones Especiales) Program in Spain.

Acanthamoeba keratitis
SIFI SpA24 enrolled5 locationsNCT07195864
Recruiting
Phase 1Phase 2

A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic Keratitis

Neurotrophic Keratitis
Krystal Biotech, Inc.60 enrolled9 locationsNCT06999733
Recruiting
Not Applicable

Intrastromal Moxifloxacin as an Adjunctive Therapy in Recalcitrant Bacterial Keratitis

Bacterial Keratitiscorneal ulcerRecalcitrant Infectious Keratitis
Minia University60 enrolled1 locationNCT07394257
Recruiting
Phase 1Phase 2

Clinical Study of Intrastromal Anti-VEGF Injection for Corneal Neovascularization.

Herpes Simplex KeratitisCorneal Neovascularization
Second Affiliated Hospital, School of Medicine, Zhejiang University100 enrolled1 locationNCT07329686
Recruiting
Phase 3

Fungal Ulcer Treatment Augmented With Natamycin and Cyclosporine A

corneal ulcerFungal Keratitis
University of California, San Francisco150 enrolled2 locationsNCT06658002
Recruiting

Complex Ocular Infection, Optimization of Microbiological Diagnosis

EndophthalmitisKeratitis
Assistance Publique - Hôpitaux de Paris153 enrolled1 locationNCT05432336
Recruiting
Phase 2

A Phase Ⅱa Study of the Safety, Tolerability and Efficacy of BD111 in Herpes Simplex Virus Type I Stromal Keratitis

Herpes Simplex Virus Type I Stromal Keratitis
Shanghai BDgene Co., Ltd.40 enrolled1 locationNCT06474442
Recruiting
Phase 4

Use of Acthar Gel Single-Dose Pre-Filled SelfJectTM Injector in Patients With Moderate-Severe Keratitis and Autoimmune Disease

Dry EyeAutoimmune DiseasesNeurotrophic Keratitis
Toyos Clinic20 enrolled1 locationNCT06964269
Recruiting
Phase 1

Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking

Bacterial KeratitisEctasia of CorneaKeratoconus, Unstable
Pacific Clear Vision Institute300 enrolled1 locationNCT03918408
Recruiting
Phase 2

Assessment of the Initial Efficacy and Safety of BRM424 Ophthalmic Solutions in Patients With Neurotrophic Keratitis

Neurotrophic Keratitis
BRIM Biotechnology Inc.12 enrolled1 locationNCT05927428
Recruiting

Use of a New Method for the Microbiological Diagnosis of Severe Corneal Infection

Microbial keratitisInfectious KeratitisCorneal Infection
CHU de Reims46 enrolled1 locationNCT05888987
Recruiting
Early Phase 1

Novel Antisense Oligonucleotide Eye Drops for Treating Antibiotic-Resistant Bacterial Keratitis

Bacterial KeratitisSensation DisordersInfections, Bacterial+7 more
Eye & ENT Hospital of Fudan University20 enrolled1 locationNCT06451172
Recruiting

OCT Evaluation of Neurotrophic Ulcer Following Treatment With Oxervate

Neurotrophic KeratitisNeurotrophic UlcerNeurotrophic Corneal Ulcer+1 more
Sight Medical Doctors PLLC10 enrolled1 locationNCT04573647
Recruiting

Non-invasive Diagnostics of Microbial Keratitis

Infectious Keratitis
Sorlandet Hospital HF125 enrolled1 locationNCT06364878
Recruiting

Corneal Collagen Cross-linking (CXL) as an adjunct in the treatment of Microbial Keratitis

Microbial keratitis
Dr Laurence Sullivan298 enrolled1 locationACTRN12611000189921
Recruiting
Phase 4

A comparison of topical anaesthesia with placebo for the managment of minor corneal trauma.

Emergency department presentations of corneal abrasion, corneal foreign bodies and UV keratitis.
Ken Barns1 locationACTRN12605000273684