Phase 2 Kidney Clinical Trials
166 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 166 trials
Recruiting
Phase 2
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
Stage IV Renal Cell Cancer AJCC v8Stage IVB Prostate Cancer AJCC v8Large Cell Neuroendocrine Carcinoma+42 more
National Cancer Institute (NCI)314 enrolled582 locationsNCT03866382
Recruiting
Phase 2
Biomarker and Renal Angina Validation to Assess Heart-Kidney Outcomes After Amino Acid Therapy
Acute Kidney InjuryMechanical Ventilation
Dana Fuhrman30 enrolled1 locationNCT07212595
Recruiting
Phase 2
A Study of Luspatercept in People With Anemia
Chronic Kidney DiseaseAnemia
Memorial Sloan Kettering Cancer Center30 enrolled7 locationsNCT07725497
Recruiting
Phase 2
A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia
End Stage Renal Disease on DialysisHyperphosphatemiaChronic Kidney Disease Requiring Chronic Dialysis
R1 Therapeutics168 enrolled31 locationsNCT06712654
Recruiting
Phase 1Phase 2
Trastuzumab Deruxtecan (DS-8201a) for the Treatment of Recurrent or Refractory Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor
OsteosarcomaRecurrent OsteosarcomaWilms Tumor+5 more
National Cancer Institute (NCI)55 enrolled28 locationsNCT04616560
Recruiting
Phase 2Phase 3
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
End-stage Kidney Disease
CSL Behring3,110 enrolled548 locationsNCT05485961
Recruiting
Phase 2
Study to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney Disease
Diabetic Kidney Disease (DKD)
Regeneron Pharmaceuticals270 enrolled57 locationsNCT07271186
Recruiting
Phase 2
Safety and Efficacy of Mesenchymal Stromal Cells (Amimestrocel ) in Diabetic Kidney Disease
Diabetic Kidney Disease (DKD)
Chinese PLA General Hospital120 enrolled6 locationsNCT06969807
Recruiting
Phase 2
Clinical Study to Evaluate the Efficacy and Safety of Mesenchymal Stromal Cells (Amimestrocel ) in Patients With Acute Kidney Injury
Acute Kidney Injury
Chinese PLA General Hospital50 enrolled6 locationsNCT06954740
Recruiting
Phase 2
Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
Breast CancerLiver CancerColorectal, Cancer+19 more
University of California, Irvine75 enrolled1 locationNCT06580002
Recruiting
Phase 2
PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease
Proteinuric Kidney Diseases
Boehringer Ingelheim132 enrolled161 locationsNCT07355296
Recruiting
Phase 1Phase 2
Breakthrough - T1DM and Chronic Kidney Disease
Chronic Kidney DiseaseDiabete Type 1
University of Chicago10 enrolled1 locationNCT07592000
Recruiting
Phase 2
A Study to Evaluate the Efficacy and Safety of BX-001N in Preventing Cardiac Surgery-Associated Acute Kidney Injury (CSA-AKI) and Major Adverse Kidney Events (MAKE)
Cardiac Surgery associated Acute kidney injuryIschemia Reperfusion Injury
Bilix Co.,Ltd.50 enrolled8 locationsNCT07164833
Recruiting
Phase 2
Perioperative Ursodeoxycholic Acid for Renal Protection in Adults Undergoing Partial Nephrectomy for Renal Tumors
Kidney Cancer
Jinling Hospital, China146 enrolled1 locationNCT07672860
Recruiting
Phase 2
The Evaluation of the Drug R3R01 for the Excretion of Protein in the Urine in Patients With Diabetic Kidney Disease.
Diabetic Kidney Disease
River 3 Renal Corp.60 enrolled1 locationNCT06600412
Recruiting
Phase 2Phase 3
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
Proteinuric Kidney Disease
Vertex Pharmaceuticals Incorporated466 enrolled318 locationsNCT05312879
Recruiting
Phase 2
Dose-Ranging Safety, Tolerability, and Efficacy Study of AZD2373 in Participants With APOL1-Mediated Kidney Disease
APOL1-mediated Kidney Disease
AstraZeneca136 enrolled89 locationsNCT06824987
Recruiting
Phase 2
A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.
SepsisAcute Kidney Injury
AstraZeneca124 enrolled72 locationsNCT07215702
Recruiting
Phase 1Phase 2
Intradialytic Exercise Combined With Creatine Monohydrate in Patients With Chronic Kidney Disease Undergoing Hemodialysis.
Chronic Kidney Disease 5D
Pedro Julian Flores Moreno48 enrolled1 locationNCT07666815
Recruiting
Phase 2Phase 3
A Study to Investigate the Efficacy and Safety of Frexalimab Versus Tacrolimus in Adults Undergoing Kidney Transplantation
Kidney Transplant Rejection
Sanofi526 enrolled26 locationsNCT07412470