Phase 2 Knee Arthroplasty Clinical Trials

9 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 19 of 9 trials

Recruiting
Phase 2

Study on BT-114143 Reducing Perioperative Bleeding in Total Knee Arthroplasty(TKA)

Total Knee Arthroplasty
ScinnoHub Pharmaceutical Co., Ltd.270 enrolled1 locationNCT07127042
Recruiting
Phase 1Phase 2

Intraosseous (IO) Cefazolin and Vancomycin in Primary Total Knee Arthroplasty (TKA)

Total Knee Arthroplasty
The Methodist Hospital Research Institute40 enrolled1 locationNCT06640491
Recruiting
Phase 2

Yale Steroid Enhanced Versus Exparel Nerveblock TKA Part 2

Total Knee ReplacementKnee Arthroplasty
Yale University66 enrolled2 locationsNCT05736549
Recruiting
Phase 2

Yale Steroid Enhanced Versus Exparel Nerveblock TKA RCT Study

Total Knee ReplacementKnee Arthroplasty
Yale University250 enrolled2 locationsNCT05279092
Recruiting
Phase 2

Post-operative Analgesic Effect of Oral Nefopam

Postoperative Pain After a Total Knee Arthroplasty
Hospices Civils de Lyon40 enrolled1 locationNCT04576078
Recruiting
Phase 1Phase 2

Mitigation of Arthrofibrosis After Total Knee Arthroplasty Using Losartan

Knee Arthroplasty, Total
Steadman Philippon Research Institute120 enrolled1 locationNCT06108063
Completed
Phase 2

An Open-Label Ascending Dose Pharmacokinetic, Safety and Tolerability Study of Treatment with TKAine System (Bupivacaine HCl Monohydrate) After Total Knee Arthroplasty (TKA)

Post-operative pain in patients following Total Knee Arthroplasty (TKA) procedures
Foundry Therapeutics 1, Pty Ltd30 enrolled2 locationsACTRN12619000775112
Completed
Phase 2

This study looks into the effects of FDY-5301 in relation to skeletal muscle loss after full knee replacement.

SarcopeniaTotal Knee Arthroplasty (TKA)
Faraday Pharmaceuticals Australia PTY LTD30 enrolled4 locationsACTRN12618001014246
Completed
Phase 2Phase 3

Does the addition of inpatient aquatic physiotherapy hasten recovery after total joint replacement surgery?

hip and knee arthroplasty
Ann Rahmann60 enrolled1 locationACTRN12608000354381