Phase 4 Knee Arthroplasty Clinical Trials
16 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–16 of 16 trials
Recruiting
Phase 4
Medrol Dosepak for Outpatient Total Knee Arthroplasty
Total Knee Arthroplasty
Rush University Medical Center420 enrolled1 locationNCT05097976
Recruiting
Phase 4
Nalbuphine Timing Effects on Hemodynamics and Analgesia in Elderly Patients
Postoperative Pain, AcuteHemodynamicsTotal Knee Arthroplasty (TKA)
Qianfoshan Hospital162 enrolled1 locationNCT07271849
Recruiting
Phase 4
A Prospective, Randomized Parallel Group Study of the Efficacy of Vancomycin Administered Through Intraarticular Injection Versus Intraosseous Injection Versus Intravenous Infusion in Patients Undergoing Total Knee Arthroplasty
Total Knee Arthroplasty
University of California, San Diego30 enrolled1 locationNCT07282782
Recruiting
Phase 4
Reducing Perioperative Oxidative Stress to Prevent Postoperative Chronic Pain Following Total Knee Arthroplasty
Osteoarthritis, KneeTotal Knee ArthroplastyChronic Postsurgical Pain
Vanderbilt University Medical Center148 enrolled1 locationNCT06083480
Not Yet Recruiting
Phase 4
Extended Postoperative Oral Tranexamic Acid In Total Hip and Knee Arthroplasty: A Randomised Controlled Study
OsteoarthritisTotal Hip ArthroplastyTotal Knee Arthroplasty
North Sydney Orthopaedic Research Group200 enrolled1 locationACTRN12625000926437
Recruiting
Phase 4
The Perioperative Outcome of Epinephrine Infusion and Tranexamic Acid in Knee Arthroplasty Surgery
Knee Arthroplasty, TotalKnee Arthritis, OsteoarthritisTotal Knee Anthroplasty
King Abdullah International Medical Research Center80 enrolled1 locationNCT07089251
Recruiting
Phase 4
Kinematic and Mechanical Alignment Randomized Trial
OsteoarthritisTotal Knee Arthroplasty
McMaster University260 enrolled1 locationNCT06787417
Completed
Phase 4
Investigating the effect of tranexamic acid on recovery time in patients undergoing total knee replacements
Peri-operative bleeding with Total Knee ArthroplastyTotal Knee Arthroplasty
Wesley Medical Research80 enrolled2 locationsACTRN12621001327875
Not Yet Recruiting
Phase 4
Investigating the effectiveness of Prophylactic Hypotension Avoidance iN arThrOplasty using Midodrine (PHANTOM) pilot trial
Hip ArthroplastySurgeryHypotension+1 more
Royal Perth Hospital166 enrolled1 locationACTRN12621000943842
Recruiting
Phase 4
Optimising pain relief after knee joint replacement surgery at Counties Manukau Health; We compare two methods of local anaesthesia (numbing medicine) administration to reduce pain after knee replacement surgery.
Pain relief after Total Knee Arthroplasty
Counties Manukau Health, Middlemore Hospital Research Office72 enrolled1 locationACTRN12619000221156
Terminated
Phase 4
A clinical trial to determine if aspirin is as effective and safe as low molecular weight heparin in preventing lung and leg clots after total hip or knee replacement surgery
Venous Thromboembolic Events (VTE) after Total Hip Arthroplasty (THA) and Total Knee Arthroplasty (TKA)
University of New South Wales15,562 enrolled1 locationACTRN12618001879257
Recruiting
Phase 4
Postoperative analgesia for elective total knee arthroplasty
Postoperative analgesia for elective total knee arthroplasty
Hospital Complex of Navarra500 enrolled1 locationACTRN12616000912482
Completed
Phase 4
Comparision of Intraoperative Epidural Analgesia and Intraoperative Periarticular Injection on Pain Control After Total Knee Arthroplasty
postoperative analgesia after total knee arthroplasty
Namik Sahin128 enrolled1 locationACTRN12616000226404
Recruiting
Phase 4
Optimizing post operative outcomes in Total Knee Arthroplasty (TKR) through improved pain and fatigue management: a randomized placebo controlled trial.
Post Operative Management of Total Knee ArthroplastyKnee Osteoarthritis
ORIQL104 enrolled1 locationACTRN12615000413527
Recruiting
Phase 4
A comparison of propofol and dexmedetomidine for sedation during hip and knee arthoplasty.
Sedation during hip and knee arthroplasty, which is often associated with a need for airway support due to respiratory depression and reduced airway tone.
Dr Mark Suss40 enrolled1 locationACTRN12612000211864
Completed
Phase 3Phase 4
Assessment of microbleeding after prophylaxis with enoxaparin or rivaroxaban against venous thromboembolic disease following hip and knee surgery
Prevention and treatment of venous thromboembolism (VTE); comprising deep vein thrombosis (DVT) and pulmonary embolism (PE) after hip and knee arthroplasty.
Launceston General Hospital1,060 enrolled1 locationACTRN12609000762257