Leg Ulcers Clinical Trials

10 recruitingLast updated: May 21, 2026

There are 10 actively recruiting leg ulcers clinical trials across 3 countries. Studies span Not Applicable, Phase 4, Phase 2. Top locations include Philidelphia, Pennsylvania, United States, Fort-de-France, France, Lyon, France. Updated daily from ClinicalTrials.gov.


Leg Ulcers Trials at a Glance

10 actively recruiting trials for leg ulcers are listed on ClinicalTrialsFinder across 6 cities in 3 countries. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in Philidelphia, Fort-de-France, and Lyon. Lead sponsors running leg ulcers studies include BioLab Holdings, Laboratoires URGO, and Kerecis Ltd..

Browse leg ulcers trials by phase

About Leg Ulcers Clinical Trials

Looking for clinical trials for Leg Ulcers? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Leg Ulcers trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Leg Ulcers clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 110 of 10 trials

Recruiting
Not Applicable

Clinical Trial Evaluating NuShield® Plus Standard of Care (SOC) Versus Standard of Care (SOC) Alone in the Management of Non-Healing Venous Leg Ulcers (VLUs)

venous leg ulcers
Organogenesis200 enrolled1 locationNCT07510412
Recruiting
Phase 4

A Multicenter, Prospective, Controlled Modified Multi-Platform Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers.

Venous UlcerDiabetic Foot UlcerUlcer+6 more
BioLab Holdings50 enrolled1 locationNCT07364630
Recruiting
Not Applicable

Study of Miro3D Wound Matrix for Healing Wounds and Ulcers in Outpatient Care

Pressure ulcersChronic woundsDiabetic Foot Ulcers (DFUs)+3 more
Reprise Biomedical, Inc.20 enrolled2 locationsNCT06939673
Recruiting
Phase 4

Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers

Diabetic Foot UlcerDiabetic FootFoot Ulcer, Diabetic+6 more
BioLab Holdings650 enrolled1 locationNCT07089602
Recruiting

A Real-World Registry of Chronic Wounds and Ulcers

pressure injuryLymphedemaSurgical Complication+17 more
U.S. Wound Registry300,000 enrolled1 locationNCT02280733
Recruiting
Not Applicable

Efficacy and Safety of Light Compression System in the Local Treatment of Mixed Leg Ulcers (PROMETHEE Clinical Investigation)

Leg Ulcers
Laboratoires URGO210 enrolled3 locationsNCT06899919
Recruiting
Not Applicable

Effectiveness of Musicotherapy in Reducing Pain Induced by Leg Ulcer Care

PainLeg UlcerDebridement Care+1 more
University Hospital Center of Martinique180 enrolled1 locationNCT06153589
Recruiting
Phase 4

Evaluating Intact Fish Skin Graft and Standard of Care Versus Standard of Care Alone in Nonhealing Venous Leg Ulcers

venous leg ulcersVenous Leg Ulcer (VLU)Venous Leg+1 more
Kerecis Ltd.150 enrolled1 locationNCT06693570
Recruiting
Not Applicable

Clinical Trial Evaluating an Amnion Membrane Allograft Intended for Use in the Management of Non- Healing Venous Leg Ulcers Versus Standard Of Care Alone

venous leg ulcers
Skye Biologics Holdings, LLC100 enrolled1 locationNCT06764953
Recruiting
Phase 2

Evaluation of glyceryl trinitrate ointment as treatment for leg ulcers

Chronic venous leg ulcers
The Prince Charles Hospital40 enrolled1 locationACTRN12616000520437