Phase 1 Leg Clinical Trials
9 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–9 of 9 trials
Recruiting
Phase 1
Study to Evaluate Safety of C-1101 Versus Sterile Saline in Adults With Chronic Painful Lumbosacral Radiculopathy
Lumbosacral RadiculopathySciaticaSciatic Radiculopathy+3 more
Consano Bio24 enrolled3 locationsNCT07264270
Recruiting
Phase 1
Novel Calcium Channel Modulators in RLS and Variants: Efficacy & Safety
Restless Leg Syndrome (RLS)Variant Restless Legs Syndrome
Beijing Friendship Hospital20 enrolled1 locationNCT07453862
Recruiting
Phase 1
Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability
chronic strokeStrokeIschemic Stroke+9 more
Johns Hopkins University20 enrolled1 locationNCT07053917
Recruiting
Phase 1Phase 2
Safety and Preliminary Efficacy of TrophiPatch, an Adipose-Derived Stromal Cell Patch for Chronic Leg Ulcers
Diabetic Foot Ulcer (DFU)Venous Leg Ulcer (VLU)
Nicolò Brembilla18 enrolled1 locationNCT07048054
Recruiting
Phase 1Phase 2
A Study of XSTEM-VLU in Patients With Difficult-to-heal Venous Leg Ulcers
Venous Leg Ulcer
Xintela AB6 enrolled4 locationsNCT05549609
Recruiting
Phase 1
Low or High Botox Dilution for the Hemiplegic Gait?
Post Stroke Spastic Hemiplegia
University of Ioannina20 enrolled1 locationNCT04630873
Recruiting
Phase 1Phase 2
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt)
Spasticity, MuscleSpastic ParaplegiaMicrocephaly+3 more
Elpida Therapeutics SPC4 enrolled1 locationNCT05518188
Withdrawn
Phase 1
A trial to evaluate the effect of Flex-Aid beverage on frequency of nocturnal foot and/or leg cramps and its safety and tolerability
Nocturnal foot and/or leg cramps
Flex Pharma, Inc.80 enrolled1 locationACTRN12615001245583
Completed
Phase 1
Can singing training can improve voice projection for people with a spinal cord injury?
Quadriplegia
Austin Health40 enrolled1 locationACTRN12607000291482