Phase 2 Leiomyosarcoma Clinical Trials
19 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–19 of 19 trials
Recruiting
Phase 2
Ph 2 Elacestrant in ER Positive Uterine Sarcomas
Estrogen Receptor Positive TumorEndometrial Stromal SarcomaUterine Sarcoma+6 more
Dana-Farber Cancer Institute30 enrolled1 locationNCT07467772
Recruiting
Phase 1Phase 2
STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas
SarcomaSolid TumorLeiomyosarcoma+1 more
STORM Therapeutics LTD107 enrolled6 locationsNCT06975293
Recruiting
Phase 2
Agnostic Therapy in Rare Solid Tumors
Cancer of Unknown PrimarySoft Tissue SarcomaCholangiocarcinoma+38 more
Instituto do Cancer do Estado de São Paulo28 enrolled8 locationsNCT06638931
Recruiting
Phase 1Phase 2
Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma
Metastatic Soft Tissue SarcomaMetastatic LeiomyosarcomaAdvanced Soft Tissue Sarcoma+5 more
National Cancer Institute (NCI)74 enrolled1 locationNCT06498648
Recruiting
Phase 2
A Study of Ivonescimab in People With Leiomyosarcoma
Leiomyosarcoma
Memorial Sloan Kettering Cancer Center20 enrolled7 locationsNCT07516925
Recruiting
Phase 2
Letrozole in Uterine Leiomyosarcoma
Uterine Leiomyosarcoma
GOG Foundation40 enrolled25 locationsNCT05649956
Recruiting
Phase 2
Trial in Patients With Metastatic or Locally Advanced Leiomyosarcoma
Soft Tissue SarcomaLeiomyosarcoma of Ovary
Italian Sarcoma Group100 enrolled17 locationsNCT04383119
Recruiting
Phase 2
Phase II Decentralized Pragmatic Trial of Adjuvant Doxorubicin - Trabectedin Chemotherapy in uLMS
Uterine Leiomyosarcoma
M.D. Anderson Cancer Center48 enrolled1 locationNCT07076186
Recruiting
Phase 2
A Study to Evaluate Tabelecleucel in Participants With Epstein Barr Virus (EBV) Associated Diseases
LeiomyosarcomaSolid Organ Transplant ComplicationsLymphoproliferative Disorders+8 more
Pierre Fabre Medicament190 enrolled40 locationsNCT04554914
Recruiting
Phase 2
Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue Sarcoma
Soft Tissue Sarcoma AdultLeiomyosarcomaSynovial Sarcomas+6 more
Oslo University Hospital110 enrolled4 locationsNCT07169344
Recruiting
Phase 2
Dose-escalated, Hypofractionated, Definitive Proton Radiotherapy for Patients With Inoperable Soft Tissue Sarcoma.
Soft Tissue Sarcoma (STS)Soft Tissue Sarcoma AdultSynovial Sarcomas+7 more
Oslo University Hospital40 enrolled2 locationsNCT07173972
Recruiting
Phase 2
XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma
Metastatic LeiomyosarcomaUnresectable Leiomyosarcoma
Northwestern University29 enrolled1 locationNCT06571734
Recruiting
Phase 2
IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS)
AngiosarcomaLeiomyosarcomaDesmoplastic Small Round Cell Tumor+4 more
Fudan University45 enrolled1 locationNCT06849986
Recruiting
Phase 2
Targeting ATR in Soft-tissue Sarcomas
Leiomyosarcoma, Adult
Institut Bergonié72 enrolled6 locationsNCT04807816
Recruiting
Phase 2
Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced Leiomyosarcoma
SarcomaLeiomyosarcoma
Gabriel Tinoco16 enrolled1 locationNCT06528769
Recruiting
Phase 2
MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma
AngiosarcomaLeiomyosarcomaSynovial Sarcoma+8 more
HRYZ Biotech Co.148 enrolled1 locationNCT06277154
Recruiting
Phase 2
Interest of Post-operative Chemotherapy in Patients With Localised Uterine Leiomyosarcoma Suspected of Having a High Risk of Recurrence Based on a Biological Test Performed on the Tumour
Leiomyosarcoma Uterus
UNICANCER198 enrolled25 locationsNCT06524583
Recruiting
Phase 2
Metronomic Trabectedin, Gemcitabine, and Dacarbazine for Soft Tissue Sarcoma
Leiomyosarcoma
Sarcoma Oncology Research Center, LLC80 enrolled1 locationNCT04535271
Active
Phase 2
Phase II basket study of an ARomatase inhibitor plus PI3KCA inhibitor or CDK4/6 inhibitor in women with hormone receptor positive recurrent/metastatic Gynaecological Neoplasms (PARAGON-II)
Platinum resistant high-grade epithelial cancers of fallopian tubeOther gynaecological cancers (excluding endometrial cancers)Endometrial stromal sarcomas+5 more
The University of Sydney182 enrolled17 locationsACTRN12621000639820