lichen planus Clinical Trials

17 recruitingLast updated: May 21, 2026

There are 17 actively recruiting lichen planus clinical trials across 13 countries. Studies span Phase 2, Not Applicable, Phase 1, Phase 3, Phase 4. Top locations include Aberdeen, United Kingdom, Bangkok, Thailand, Beijing, China. Updated daily from ClinicalTrials.gov.


lichen planus Trials at a Glance

17 actively recruiting trials for lichen planus are listed on ClinicalTrialsFinder across 6 cities in 13 countries. The largest study group is Phase 2 with 6 trials, with the heaviest enrollment activity in Aberdeen, Bangkok, and Beijing. Lead sponsors running lichen planus studies include University of Palermo, Catholic University of the Sacred Heart, and Cairo University.

Browse lichen planus trials by phase

About lichen planus Clinical Trials

Looking for clinical trials for lichen planus? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new lichen planus trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about lichen planus clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 117 of 17 trials

Recruiting

Rate of Malignant Transformation and Clinical Characteristics Among an Oral Lichen Planus Cohort: a Retrospective Center Experience

Oral Lichen PlanusOral CarcinomaOral Carcinoma in Situ
Catholic University of the Sacred Heart300 enrolled1 locationNCT06934863
Recruiting
Not Applicable

Photobiomodulation, Photodynamic Therapy, and Clobetasol in the Treatment of Oral Lichen Planus.

Oral Lichen PlanusErosive Lichen PlanusMucosal Lesions
Medical University of Silesia60 enrolled1 locationNCT07278999
Recruiting
Not Applicable

The Therapeutic Effect of Curcumin in Nanogels Compared to 0.1% FAO in the Management of Oral Lichen Planus

Oral Lichen Planus
Chulalongkorn University30 enrolled1 locationNCT06932848
Recruiting
Phase 2

Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Oral Lichen Planus

Oral Lichen Planus
Cairo University42 enrolled1 locationNCT06981767
Recruiting
Not Applicable

VALOR: Vaginal Atrophy & Long-term Observation of Recovery

Atrophic vaginitisGenitourinary Syndrome of MenopauseVaginal Atrophy+3 more
Stratpharma AG2,000 enrolled14 locationsNCT05953090
Recruiting
Phase 2Phase 3

Treatment Outcomes and Patient Satisfaction of Oral Lichen Planus Treatment

Erosive Oral Lichen PlanusAtrophic Lichen Planus
Dar Al Uloom University56 enrolled1 locationNCT06988527
Recruiting
Phase 4

Evaluation of Efficacy and Safety of add-on Tofacitinib in Patients With Oral Lichen Planus

Oral Lichen Planus
All India Institute of Medical Sciences, Bhubaneswar60 enrolled1 locationNCT07131813
Recruiting
Phase 2

The Efficacy of Tranexamic Acid in the Treatment of Lichen Planus Pigmentosus and Erythema Dyschromicum Perstans

Lichen Planus PigmentosusErythema Dyschromicum PerstansAshy Dermatosis of Ramirez
Henry Ford Health System5 enrolled1 locationNCT04233749
Recruiting
Phase 2

Mucoadhesive Modified-Release Formulations for the Topical Treatment of Symptomatic Oral Lichen Planus

Oral Mucosal DiseaseOral Lichen PlanusOral Lichen Planus Related Stress+1 more
University of Palermo45 enrolled1 locationNCT07100613
Recruiting

Determinants of Chronic Inflammatory Skin Disease Trajectories

lichen planusRosaceaAlopecia Areata+5 more
University Hospital Schleswig-Holstein1,000 enrolled1 locationNCT05928169
Recruiting
Not Applicable

Cellular and Molecular Biomarkers in Patients With Lichen Planus

lichen planus
Institut Pasteur70 enrolled6 locationsNCT06451744
Recruiting

SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography

Oral CancerOral Squamous Cell CarcinomaActinic Keratoses+9 more
University of Palermo200 enrolled1 locationNCT06321003
Recruiting
Phase 1Phase 2

Evaluation of the Efficacy of 0.08% Tacrolimus Nanoencapsulated Aqueous Solution Spray Vs. 0.1% Free Tacrolimus Commercial Ointment in the Treatment of Oral Lichen Planus

Oral Erosive Lichen Planus
Hospital de Clinicas de Porto Alegre46 enrolled1 locationNCT06591884
Recruiting

Clinical and Molecular Correlates of Response to First Line Treatment in Lichen Planus

Lichen Planus of VulvaLichen Planus, Oral
University of Aberdeen110 enrolled2 locationsNCT05330572
Recruiting
Not Applicable

Treatment of Oral Lichen Planus With Paeoniflorin and Photodynamic Therapy

Oral Lichen Planus
Peking University Third Hospital156 enrolled1 locationNCT05973097
Recruiting
Phase 2

The Efficacy and Safety of Deucravacitinib to that of Methotrexate, in Patients with Vulvar Lichen Planus who have Failed Topical Therapy with Potent Corticosteroids: A Randomized Controlled Trial

Vulvar Lichen Planus
Dr Rebecca Bronwyn Saunderson116 enrolled1 locationACTRN12623000682640
Recruiting

Prediction of Malignant Transformation of Oral Leukoplakia Using a MAGE-A-based Immunoscore

Oral LeukoplakiaOral Leukoplakia of TongueOral Leukoplakia of Gingiva+1 more
University of Erlangen-Nürnberg Medical School500 enrolled1 locationNCT03975322