Phase 1 Liver Cirrhosis Clinical Trials

4 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 1–4 of 4 trials

Recruiting

Phase 1

Direct Oral Anticoagulants (Rivaroxaban and Apixaban) in Patients With Liver Cirrhosis

Liver Cirrhosis

Insel Gruppe AG, University Hospital Bern24 enrolled1 locationNCT04874428

Recruiting

Phase 1Phase 2

RTX001 Autologous Engineered Macrophages for Liver Cirrhosis

Liver DiseasesCirrhosis, LiverDecompensated Liver Cirrhosis+5 more

Resolution Therapeutics Limited30 enrolled14 locationsNCT06823713

Recruiting

Phase 1Phase 2

CRISPR-Edited HLA Donor Liver Transplant to Reduce Rejection

Liver CancerLiver MetastasesLiver Cirrhosis+4 more

AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC90 enrolled1 locationNCT07053488

Completed

Phase 1

A Phase 1 Single and Multiple Ascending Dose Study to Assess the Safety and Pharmacokinetics of SZN-043, a Novel Bispecific Fusion Protein Targeting ASGR1 and ZNRF3/RNF43, in Healthy Volunteers and Subjects with Liver Cirrhosis

Alcoholic HepatitisLiver Cirrhosis

Surrozen Operating, Inc.40 enrolled1 locationACTRN12622000392763