Phase 1 Liver Failure Clinical Trials

9 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 19 of 9 trials

Recruiting
Phase 1Phase 2

Safety and Tolerability Study of a Novel Bioartificial Liver in Liver Failure and Small-for-Size Syndrome

Liver FailureSmall-for-Size Syndrome
Beijing Friendship Hospital12 enrolled1 locationNCT07312864
Recruiting
Phase 1

Safety and Effectiveness of Mesenchymal Stem Cells in Blood Purification for the Treatment of Liver Failure

Liver Failure
Kebo Zhong10 enrolled1 locationNCT06904755
Recruiting
Phase 1

Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver Impairment

Advanced or Metastatic Solid TumorLiver Failure
Gilead Sciences30 enrolled13 locationsNCT04617522
Recruiting
Phase 1

The Microbiota Augmentation to Reestablish Commensal Organisms (MARCO) Trial

Liver DiseasesCirrhosis, LiverLiver Failure
University of Chicago24 enrolled1 locationNCT06871111
Recruiting
Phase 1Phase 2

CRISPR-Edited HLA Donor Liver Transplant to Reduce Rejection

Liver CancerLiver MetastasesLiver Cirrhosis+4 more
AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC90 enrolled1 locationNCT07053488
Recruiting
Phase 1

Micro-encapsulated Hepatocyte Intraperitoneal Transplantation in Liver Failure Adults

Acute-On-Chronic Liver FailureChronic Liver Failure
RenJi Hospital10 enrolled1 locationNCT05727722
Recruiting
Phase 1Phase 2

The Safety ,Tolerability and Efficacy Study of HepaCure in Chinese Subjects with Acute-On-Chronic Liver Failure

HepatitisLiver FailureAcute on Chronic Hepatic Failure
Hexaell Biotech Co., Ltd.92 enrolled1 locationNCT05989958
Recruiting
Phase 1Phase 2

Efficacy and Safety of BMSCs (CG-BM1) for ACLF Patients

Acute-On-Chronic Liver Failure
Sun Yat-sen University90 enrolled1 locationNCT06740149
Recruiting
Phase 1Phase 2

Human Umbilical Cord Mesenchymal Stem Cell Transplantation for The Treatment of Acute-on-Chronic Liver Failure

Acute-On-Chronic Liver Failure
Beijing 302 Hospital150 enrolled1 locationNCT05985863