Locally Advanced Clinical Trials in Shanghai, Shanghai Municipality

38 recruitingShanghai, Shanghai Municipality, China

Showing 120 of 38 trials

Recruiting
Phase 3

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or CancerLocally Advanced Unresectable Gastric Adenocarcinoma or CancerMetastatic Gastric Adenocarcinoma or Cancer+1 more
Astellas Pharma Global Development, Inc.500 enrolled224 locationsNCT06901531
Recruiting
Phase 1

A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors

Locally Advanced or Metastatic Solid Tumors
ArriVent BioPharma, Inc.405 enrolled15 locationsNCT07066657
Recruiting
Phase 1

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AST2303 Tablets (ABK3376 Tablets) in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer

Locally Advanced or Metastatic Non-small Cell Lung Cancer
Allist Pharmaceuticals, Inc.120 enrolled1 locationNCT06955988
Recruiting
Phase 1Phase 2

A Phase I/II Study of FWD1802 in Patients With ER+/HER2- Advanced BC.

Metastatic Breast CancerLocally Advanced Breast CancerBreast Cancer Stage IV+1 more
Forward Pharmaceuticals Co., Ltd.99 enrolled22 locationsNCT06064812
Recruiting
Phase 3

A Trial of SHR-A1811 Compared to Other Antitumor Therapies as Neoadjuvant Treatments in Early-stage or Locally Advanced HER2-positive Breast Cancer

Early-stage or Locally Advanced HER2-positive Breast Cancer
Jiangsu HengRui Medicine Co., Ltd.740 enrolled2 locationsNCT07196774
Recruiting
Phase 2

Induction Chemotherapy Combined With Tislelizumab for Locally Advanced Squamous Cell Carcinoma of the External Auditory Canal

Squamous Cell Carcinoma of External Auditory CanalLocally Advanced Tumor
Eye & ENT Hospital of Fudan University50 enrolled1 locationNCT07370337
Recruiting
Phase 2

IRE Combined With the Dual-Function Antibody PD-1/CTLA-4 for the Treatment of LAPC Following Failure of First-Line AG Therapy

Pancreatic Adenocarcinoma Locally Advanced
Ruijin Hospital20 enrolled1 locationNCT07306273
Recruiting
Phase 2

Cryoablation Combined With the Dual-Function Antibody PD-1/CTLA-4 for the Treatment of LAPC Following Failure of First-Line AG Therapy

Pancreatic Adenocarcinoma Locally Advanced
Ruijin Hospital20 enrolled1 locationNCT07306286
Recruiting
Phase 2

A Study of Osimertinib-based Adaptive Treatment Guided by ctDNA EGFRm+ Monitoring in NSCLC

Locally Advanced or Metastatic EGFRm Non-small Cell Lung Cancer (NSCLC)
Shanghai Chest Hospital250 enrolled1 locationNCT07058519
Recruiting
Phase 2

A Study of YL202 in Selected Patients With Advanced Solid Tumors

Breast CancerNSCLCHNSCC+1 more
MediLink Therapeutics (Suzhou) Co., Ltd.200 enrolled82 locationsNCT06107686
Recruiting
Phase 3

Phase III Trial of SYS6010 Versus Platinum-based Chemotherapy for EGFR-mutated NSCLC(SYNSTAR01)

EGFR-mutated Locally Advanced or Metastatic NSCLC
CSPC Megalith Biopharmaceutical Co.,Ltd.380 enrolled1 locationNCT06927986
Recruiting
Phase 1

A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Solid Tumor

Locally Advanced or Metastatic Solid Tumor
Sichuan Baili Pharmaceutical Co., Ltd.570 enrolled8 locationsNCT05194982
Recruiting
Phase 3

A Study of SIM0270 Combined With Everolimus vs. Treatment of Physician's Choice in Patients With ER+/HER2- Advanced Breast Cancer (SIMRISE)

Locally Advanced or Metastatic Breast Cancer
Jiangsu Simcere Pharmaceutical Co., Ltd.460 enrolled60 locationsNCT06680921
Recruiting
Phase 3

Adjuvant Study of Pyrotinib in HER-2 Positive Breast Cancer

Locally Advanced Breast Cancer
RenJi Hospital316 enrolled1 locationNCT04254263
Recruiting
Phase 2

A Single-arm, Open-label, Single-center Prospective Study of Fruquintinib Combined With Envafolimab in the Treatment of Advanced or Unresectable Locally Advanced Bone and Soft Tissue Sarcoma

Advanced or Unresectable Locally Advanced Bone and Soft Tissue Sarcoma
Shanghai 6th People's Hospital20 enrolled1 locationNCT05941325
Recruiting
Phase 3

Clinical Study of Tumor Treating Fields Combined with Gemcitabine and Albumin-bound Paclitaxel in the First-line Treatment of Locally Advanced Pancreatic Cancer

Locally Advanced Pancreatic Cancer
Jiangsu Healthy Life Innovation Medical Technology Co., Ltd512 enrolled5 locationsNCT05653453
Recruiting
Phase 2

A Phase 2 Study to Evaluate the Efficacy, Safety and Pharmacokinetics of YL202 in Patients With BC

Locally Advanced or Metastatic Breast Cancer
MediLink Therapeutics (Suzhou) Co., Ltd.180 enrolled1 locationNCT06439771
Recruiting
Phase 1Phase 2

De-escalation Radiation Strategy After NAC in Combination With ICI in LAHNSCC

Locally Advanced Head and Neck Squamous Cell Carcinoma
Ruijin Hospital20 enrolled1 locationNCT06572514
Recruiting
Phase 1Phase 2

TSN222 in Subjects With Advanced Solid Tumors or Lymphomas

Has a Pathologically Documented Unresectable Locally Advanced or Metastatic Solid Tumor or Lymphoma
Tyligand Bioscience (Shanghai) Limited162 enrolled1 locationNCT05842785
Recruiting
Phase 3

A Trial of SHR3680 in Prostate Cancer Patients Who Are Candidates for Radical Prostatectomy

Patients With High-risk Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy
Jiangsu HengRui Medicine Co., Ltd.1,256 enrolled1 locationNCT05009290