Early Phase 1 Locally Advanced Clinical Trials
8 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–8 of 8 trials
Recruiting
Early Phase 1
First-in-human Study of the Theranostic Pair [68Ga]Ga DOTA-5G and [177Lu]Lu DOTA-ABM-5G in Pancreatic Cancer
Metastatic Pancreatic CancerLocally Advanced Pancreatic Adenocarcinoma
University of California, Davis30 enrolled1 locationNCT04665947
Recruiting
Early Phase 1
OMO-103 for the Treatment of Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma
Stage II Pancreatic Cancer AJCC v8Stage III Pancreatic Cancer AJCC v8Stage IV Pancreatic Cancer AJCC v8+2 more
OHSU Knight Cancer Institute12 enrolled1 locationNCT07089940
Recruiting
Early Phase 1
Targeted Pathway Inhibition in Patients With Pancreatic Cancer
Stage II Pancreatic Cancer AJCC v8Stage III Pancreatic Cancer AJCC v8Stage IV Pancreatic Cancer AJCC v8+5 more
OHSU Knight Cancer Institute90 enrolled1 locationNCT04005690
Recruiting
Early Phase 1
Neoadjuvant Therapy and Contrast-enhanced Mammography for Early Stage Breast Cancer
Breast CancerHER2-positive Breast CancerLocally Advanced Breast Cancer+1 more
Alison Stopeck30 enrolled1 locationNCT06220214
Recruiting
Early Phase 1
An Investigational Scan (64Cu-Labeled M5A Antibody) in Combination With SOC Chemotherapy and Radiotherapy in Locally Advanced Rectal Cancer
Locally Advanced Rectal CarcinomaStage III Rectal Cancer AJCC v8Stage IIIA Rectal Cancer AJCC v8+2 more
City of Hope Medical Center15 enrolled1 locationNCT05245786
Recruiting
Early Phase 1
Study of CBL0137 in Combination With Ipilimumab and Nivolumab Therapy in Melanoma
Locally Advanced or Metastatic Melanoma
Fox Chase Cancer Center12 enrolled1 locationNCT05498792
Recruiting
Early Phase 1
Neoadjuvant Dupilumab, Pembrolizumab, Paclitaxel, and Carboplatin in Locally Advanced Triple Negative Breast Cancer
TNBC - Triple-Negative Breast CancerLocally Advanced Triple Negative Breast Cancer
Rima Patel15 enrolled1 locationNCT06637306
Recruiting
Early Phase 1
Exercise for Improving Long-course Chemoradiotherapy Efficacy in People With Locally Advanced Rectal Cancer
Locally Advanced Rectal Carcinoma
University of Hull30 enrolled1 locationNCT06276686