Phase 4 Locally Advanced Clinical Trials

5 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 1–5 of 5 trials

Recruiting

Phase 4

Study Aiming to Compare the Plasma Exposure of the Payload (Free-DXd) in Patients Treated by T-DXd for Locally Advanced or Metastatic Breast Cancer According to Their BMI.

Locally Advanced or Metastatic Breast Cancers

Institut Claudius Regaud210 enrolled11 locationsNCT07195344

Recruiting

Phase 4

Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial

Metastatic Bladder Urothelial CarcinomaStage IV Bladder Cancer AJCC v8Metastatic Renal Pelvis and Ureter Urothelial Carcinoma+4 more

Mayo Clinic75 enrolled1 locationNCT06764095

Recruiting

Phase 4

Digital Monitoring of Self-reported Symptoms by Patients Treated With Cabozantinib Plus Nivolumab for Advanced Clear-cell Renal Carcinoma

Metastatic Renal Cell CarcinomaLocally AdvancedRenal Cell Carcinoma (Kidney Cancer)

Centre Francois Baclesse83 enrolled10 locationsNCT07028125

Recruiting

Phase 4

Safety and Efficacy of Pembrolizumab in Combination with Bevacizumab + CapeOX in the Neoadjuvant Treatment of RAS-mutated, BRAF Wild-type, Microsatellite-stabilized, Locally Advanced Colorectal Cancer

Locally Advanced Colorectal Cancer

yangjianjun20 enrolled1 locationNCT06550453

Recruiting

Phase 4

Select the Appropriate Population for Adding CDK4/6i to Neoadjuvant Endocrine Therapy

Locally Advanced Breast CancerHormone Receptor Positive，HER2-negative Breast Cancer

Yongsheng Wang100 enrolled1 locationNCT05809024