Early Phase 1 Lung Clinical Trials
24 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 24 trials
Recruiting
Early Phase 1
Early Use of Long-acting Tacrolimus in Lung Transplant Recipients
Lung Transplant; Complications
Vanderbilt University Medical Center48 enrolled1 locationNCT04469842
Recruiting
Early Phase 1
PET Imaging CCR2 in Lung Inflammation
Lung Inflammation
Washington University School of Medicine110 enrolled1 locationNCT03492762
Recruiting
Early Phase 1
Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA CAR-NK Cell Injection for the Treatment of Refractory Pediatric Rheumatic Diseases
Systemic Lupus Erythematosus (SLE)Rheumatic DiseasesPediatric Rheumatological Condition (i.e., Arthritis, SLE, Kawasaki's Disaese)+1 more
The Children's Hospital of Zhejiang University School of Medicine36 enrolled1 locationNCT07490041
Recruiting
Early Phase 1
Hydroxychloroquine in Children's Interstitial Lung Diseases With Genetic Causes
Interstitial Lung DiseaseSurfactant Dysfunction
Children's Hospital of Fudan University60 enrolled1 locationNCT04532346
Recruiting
Early Phase 1
Testing the Safety of Dapagliflozin Prior to Surgery for the Treatment of Patients With Stage IA Lung Adenocarcinoma
Lung CancerLung AdenocarcinomaStage IA1 Lung Cancer American Joint Committee on Cancer (AJCC) v8+2 more
Jonsson Comprehensive Cancer Center48 enrolled1 locationNCT07235280
Recruiting
Early Phase 1
177Lu-anti-PD-L1 sdAb in Metastatic Solid Tumors
Endometrial CancerNon-small Cell Lung CancerTNBC - Triple-Negative Breast Cancer+6 more
Radiopharm Theranostics, Ltd30 enrolled5 locationsNCT06305962
Recruiting
Early Phase 1
Low-Dose Interleukin-2 and Pembrolizumab for the Treatment of Stage IV Non-Small Cell Lung Cancer
Stage IV Lung Cancer AJCC v8Stage IVA Lung Cancer AJCC v8Stage IVB Lung Cancer AJCC v8+1 more
Emory University15 enrolled1 locationNCT05493566
Recruiting
Early Phase 1
Autologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer
Lung CancerNon-small Cell Lung CancerSmall Cell Lung Carcinoma
UNC Lineberger Comprehensive Cancer Center24 enrolled1 locationNCT05620342
Recruiting
Early Phase 1
[177Lu]Lu-AKIR001 First-in-human Study
Thyroid Gland Anaplastic CarcinomaPoorly Differentiated Thyroid CarcinomaCancer Head and Neck+3 more
Karolinska University Hospital15 enrolled1 locationNCT06639191
Recruiting
Early Phase 1
Universal CAR-T Cells (REVO-UWD-03) for Advanced Hepatocellular Carcinoma and Lung Cancer
NSCLC (Advanced Non-small Cell Lung Cancer)HCC - Hepatocellular Carcinoma
Wondercel Biotech (ShenZhen)60 enrolled2 locationsNCT06653023
Recruiting
Early Phase 1
Inhaled mRNA Tumor-associated Antigen Dry Powder Vaccine in Advanced Lung Cancer and Lung Metastasis of Solid Tumors.
Advanced Lung CancerLung Metastasis
Cancer Institute and Hospital, Chinese Academy of Medical Sciences83 enrolled1 locationNCT06928922
Recruiting
Early Phase 1
PET-imaging of Two Vartumabs in Patients With Solid Tumors
Breast CancerBladder CarcinomaEsophageal Carcinoma+11 more
Var2 Pharmaceuticals32 enrolled1 locationNCT06645808
Recruiting
Early Phase 1
TC-D101 Cell Therapy for Patients With DLL3-Positive SCLC
Small Cell Lung Cancer ( SCLC )CAR-T Cell Therapy
TCRCure Biopharma Ltd.24 enrolled1 locationNCT07246304
Recruiting
Early Phase 1
Feasibility Study of Personalized Ultra-fractionated Stereotactic Ablative Radiotherapy (PULSAR) for Cancers of the Central Lung
MetastasisCancer, Lung
University of Texas Southwestern Medical Center30 enrolled1 locationNCT06712745
Recruiting
Early Phase 1
FAPI PET for Lung Fibrosis
PneumoconiosisRadiation PneumonitisInterstitial Lung Disease+4 more
University of California, Los Angeles30 enrolled1 locationNCT05365802
Recruiting
Early Phase 1
68Ga-FAPI-RGD PET/CT Imaging in the Lung Cancer Patients
Lung Neoplasms
Peking Union Medical College Hospital60 enrolled1 locationNCT05543954
Recruiting
Early Phase 1
EGFR/B7H3 CAR-T on Lung Cancer and Triple Negative Breast Cancer
EGFR/ B7H3-positive Advanced Lung CancerEGFR/ B7H3-positive Advanced Triple-negative Breast Cancer
Second Affiliated Hospital of Guangzhou Medical University30 enrolled1 locationNCT05341492
Recruiting
Early Phase 1
Study of CXCR5 Modified EGFR Targeted CAR-T Cells for Advanced NSCLC
Non-small Cell Lung Cancer
Second Affiliated Hospital of Guangzhou Medical University11 enrolled1 locationNCT05060796
Recruiting
Early Phase 1
An Exploratory Study of Efficacy and Safety of Iruplinalkib Tablets in Patients With ROS1 Positive Non-small Cell Lung Cancer
Non-small Cell Lung Cancer
Henan Cancer Hospital39 enrolled1 locationNCT06436885
Recruiting
Early Phase 1
WTX212A Monotherapy and in Combination With PD -1/PD-L1 Monoclonal Antibody
Advanced Lung Cancer
Second Affiliated Hospital, School of Medicine, Zhejiang University20 enrolled1 locationNCT06106152