Phase 1 Malignant Pleural Effusion Clinical Trials

7 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 17 of 7 trials

Recruiting
Phase 1

Fast TILs to Treat Metastatic Pleural Effusions From Epithelial or Mesothelial Primary Tumors

Pleural Effusion, MalignantMalignant MesotheliomaMalignant Pleural Effusion+1 more
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)10 enrolled1 locationNCT07443020
Recruiting
Phase 1

Fast TILs to Treat Metastatic Cancer Patients With Pleural Disease

Pleural Effusion, MalignantMalignant MesotheliomaMalignant Pleural Effusion+1 more
David Bartlett, MD10 enrolled1 locationNCT07192900
Recruiting
Phase 1Phase 2

A Phase Ib/II Clinical Trial of M701 in the Treatment of Malignant Pleural Effusions Caused by NSCLC

NSCLC Stage IVMalignant Pleural Effusions
Wuhan YZY Biopharma Co., Ltd.96 enrolled1 locationNCT05543330
Recruiting
Phase 1

Tocilizumab Delivered Via Pleural and Peritoneal Catheters in Patients With Advanced Metastatic Cancer

Malignant Pleural Effusion
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)12 enrolled1 locationNCT06016179
Recruiting
Phase 1

A Phase Ib Study of JMKX000197 Injection in the Treatment of Malignant Pleural Effusion

Malignant Pleural Effusions (Mpe)
Jemincare30 enrolled1 locationNCT06740019
Recruiting
Phase 1

A Study of MT027 in Patients with Pleural Malignant Tumors

Malignant Pleural EffusionAdvanced Malignant Solid TumorPleural Metastases+3 more
Suzhou Maximum Bio-tech Co., Ltd.18 enrolled1 locationNCT06726564
Recruiting
Phase 1

OPC5: Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) in Patients With Malignant Pleural Effusion.

Pleural CarcinomatosisQuality of LifeChemotherapy Effect+4 more
Odense University Hospital20 enrolled1 locationNCT06421610