Early Phase 1 Men Clinical Trials
51 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 51 trials
Recruiting
Early Phase 1
Repeated CBD Administration and Cannabis Outcomes
CannabisAbuse LiabilityExperimental Pain in Healthy Human Participants
Hannah Harris23 enrolled1 locationNCT07434895
Recruiting
Early Phase 1
MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction (MOCHA Trial)
Post-traumatic OsteoarthritisACL InjuryMeniscus Tear
Austin V Stone30 enrolled1 locationNCT04572256
Recruiting
Early Phase 1
Educational Support Group Program for Bilingual and Spanish-speaking Carepartners and People With Progressive Aphasia
DementiaAlzheimer DiseaseProgressive Aphasia+3 more
University of Texas at Austin120 enrolled1 locationNCT06511752
Recruiting
Early Phase 1
Development of a Preparation for Supportive Supplementation of Probiotics in Patients With Reflux
MicrobiomeReflux DiseaseProbiotics Supplement
University Hospital Olomouc50 enrolled1 locationNCT07600008
Recruiting
Early Phase 1
Replacement of the Native Mitral Valve Using the ReValve System
Mitral Valve Replacement
ReValve Solutions Inc.25 enrolled2 locationsNCT07601269
Recruiting
Early Phase 1
Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease
Alzheimer DiseaseMild Cognitive ImpairmentLogopenic Progressive Aphasia+1 more
Massachusetts General Hospital30 enrolled1 locationNCT06538311
Recruiting
Early Phase 1
Personalized DBS Targeting for Treating Depression
Treatment Resistant Depression (TRD)
Second Affiliated Hospital, School of Medicine, Zhejiang University5 enrolled1 locationNCT06784388
Recruiting
Early Phase 1
Intraoperative Contrast-Enhanced Ultrasound Evaluation of Blood Flow at the Time of Surgical Hip Reduction for DDH
Developmental Dysplasia of the Hip
Children's Hospital of Philadelphia125 enrolled1 locationNCT03107520
Recruiting
Early Phase 1
Effect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients
Arterial HypertensionMicrovascular FunctionResistant Hypertension+1 more
National Institute of Cardiology, Laranjeiras, Brazil50 enrolled1 locationNCT06169241
Recruiting
Early Phase 1
Safety and Efficacy Study of Novel Gene Therapy ZM-02 for Retinitis Pigmentosa Patients
Retinitis Pigmentosa
Zhongmou Therapeutics12 enrolled1 locationNCT06292650
Recruiting
Early Phase 1
Ceftriaxone Pulse Dose for Post-Treatment Lyme Disease
Post-Treatment Lyme Disease
State University of New York - Upstate Medical University44 enrolled1 locationNCT06611111
Recruiting
Early Phase 1
Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease
DepressionDepressive SymptomsAlzheimer Disease+1 more
Johns Hopkins University20 enrolled1 locationNCT04123314
Recruiting
Early Phase 1
Human Amniotic-Derived Mesenchymal Stem Cell Therapy for Calciphylaxis
EfficacyTreatmentChronic Kidney Diseases+3 more
The First Affiliated Hospital with Nanjing Medical University9 enrolled1 locationNCT04592640
Recruiting
Early Phase 1
Effects of Nicotinamide Riboside on Bioenergetics and Oxidative Stress in Mild Cognitive Impairment/Alzheimer's Dementia
Mild Cognitive ImpairmentMild Alzheimer Disease
Mclean Hospital50 enrolled1 locationNCT04430517
Recruiting
Early Phase 1
Ketamine for Shoulder Pain Following Laparoscopic Gastric Sleeve Surgery
Pain ManagementLaparascopic Sleeve Gastrectomy
King Abdullah University Hospital50 enrolled1 locationNCT07429916
Recruiting
Early Phase 1
Biologic Therapy to Prevent Osteoarthritis After ACL Injury
Anterior Cruciate Ligament Injuries
University of California, Los Angeles32 enrolled1 locationNCT03968913
Recruiting
Early Phase 1
Efficacy and Safety Study of DC-CIK Cell Therapy Combined With Epaloliposide, Vortexil, and Regorafenib as Third-line Treatment for Advanced Colorectal Cancer.
Colorectal, CancerDC-CIK TreatmentRegorafenib+2 more
JIANG LONGWEI14 enrolled1 locationNCT07343791
Recruiting
Early Phase 1
Nutrition in Patient With Critical Limb Ischemia
MalnutritionNutritional SupplementsCritical Limb Ischemia
Boston Medical Center30 enrolled1 locationNCT03529019
Recruiting
Early Phase 1
PET Imaging Evaluation of [11C]SY08
Multiple System AtrophyDementia With Lewy BodiesParkinson's Disease+1 more
Massachusetts General Hospital40 enrolled1 locationNCT06098612
Recruiting
Early Phase 1
Time-in-bed Restriction in Older Adults With Sleep Difficulties With and Without Risk for Alzheimer's Disease
Cognitive ChangeSleepMild Cognitive Impairment+2 more
University of Pittsburgh116 enrolled1 locationNCT05138848