RecruitingEarly Phase 1NCT07434895

Repeated CBD Administration and Cannabis Outcomes

The Effects of Repeated CBD Administration on Cannabis Abuse Liability and Analgesia: A Human Laboratory Study

Sponsor

Hannah Harris

Enrollment

23 participants

Start Date

Jul 29, 2026

Study Type

INTERVENTIONAL

Conditions

Cannabis Abuse Liability Experimental Pain in Healthy Human Participants

Summary

This outpatient study examines how cannabidiol (CBD) affects the behavioral and pain-relieving effects of cannabis.

Eligibility

Min Age: 18 YearsMax Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Active Inhaled Cannabis, a drug called Cannabidiol, Higher Dose, and others for people with abuse liability, cannabis, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 55 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGCannabidiol, Medium Dose

Active Cannabidiol: Active cannabidiol (medium dose) will be administered orally for 14 days.

DRUGCannabidiol, Higher Dose

Description: Active Cannabidiol: Active cannabidiol (higher dose) will be administered orally for 14 days.

DRUGActive Inhaled Cannabis

Active Marijuana: Active Marijuana (active inhaled cannabis) will be administered through a vaporizer once per study session day (Day 1, 7, 14) per block (3 blocks total).

DRUGPlacebo Cannabidiol

Inactive/Placebo Cannabidiol: Inactive/placebo cannabidiol will be administered orally for 14 days.

DRUGPlacebo Inhaled Cannabis

Inactive/Placebo Marijuana: Experimental, non-therapeutic administration of an inactive/placebo marijuana dose will be administered through a vaporizer at each study session day (Days 1, 7, 14) per block (3 blocks total).