Phase 1 Metabolism Clinical Trials
4 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–4 of 4 trials
Recruiting
Phase 1Phase 2
A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus
Metabolic DiseaseDiabetes Mellitus, Type 1Type 1 Diabetes+14 more
Otsuka Pharmaceutical Factory, Inc.13 enrolled1 locationNCT06575426
Not Yet Recruiting
Phase 1
A study to assess the safety of increasing single doses of AP003 in healthy adults.
Liver-associated inborn errors of metabolismArg-TGA premature termination codon mutationsLiver stop codon disease+1 more
Alltrna, Incorporated30 enrolled1 locationACTRN12626000194369
Recruiting
Phase 1Phase 2
An Open-Label, FIH Study Evaluating the Safety, Tolerability, and Efficacy of VCTX211 Combination Product in Subjects With T1D
Diabetes MellitusMetabolic DiseaseDiabetes Mellitus, Type 1+4 more
CRISPR Therapeutics AG40 enrolled2 locationsNCT05565248
Completed
Phase 1
Effects of sitagliptin, a dipeptidyl peptidase IV (DPP IV) inhibitor, on blood glucose and plasma incretin and insulin responses to small intestinal glucose infusion, in healthy lean and obese subjects, and alone or in combination with metformin in patients with type 2 diabetes mellitus.
Incretin hormone secretion and metabolism
Royal Adelaide Hospital36 enrolled1 locationACTRN12608000433303