Metabolism Clinical Trials

19 recruiting

Metabolism Trials at a Glance

106 actively recruiting trials for metabolism are listed on ClinicalTrialsFinder across 6 cities in 28 countries. The largest study group is Not Applicable with 53 trials, with the heaviest enrollment activity in Aurora, Seattle, and New York. Lead sponsors running metabolism studies include University of Texas Southwestern Medical Center, Hospital Universitari Vall d'Hebron Research Institute, and Colorado State University.

Browse metabolism trials by phase

Treatments under study

About Metabolism Clinical Trials

Looking for clinical trials for Metabolism? There are currently 19 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Metabolism trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Metabolism clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 106 trials

Recruiting
Phase 2

Regulation of Endogenous Glucose Production by Central KATP Channels

Diabetes MellitusGlucose Metabolism Disorders
Albert Einstein College of Medicine100 enrolled1 locationNCT03540758
Recruiting
Not Applicable

Amino Acid Metabolism in Fed Surgical Critically Ill Patients

Metabolism and Nutrition Disorder
Rabin Medical Center30 enrolled1 locationNCT03451968
Recruiting
Not Applicable

Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes

Insulin ResistanceHyperinsulinismDepression+5 more
Colorado State University300 enrolled2 locationsNCT05543083
Recruiting
Not Applicable

Effect of Ilex Paraguariensis Harvest Time and Consumption Method of Processed Yerba Mate on the Lipid Profile

Lipid Metabolism Disorders
Universidad Nacional de Caaguazu198 enrolled1 locationNCT06896175
Recruiting
Phase 4

Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure

Heart FailureCardiogenic ShockKetone Body Metabolism+2 more
Institute for Clinical and Experimental Medicine12 enrolled1 locationNCT07527156
Recruiting

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

Hematologic MalignanciesInherited Disorders of MetabolismInherited Abnormalities of Platelets+2 more
Center for International Blood and Marrow Transplant Research99,999 enrolled142 locationsNCT01351545
Recruiting

Clinical and Laboratory Study of Methylmalonic Acidemia

Inborn Errors of MetabolismOrganic AcidemiaMethylmalonic Acidemia
National Human Genome Research Institute (NHGRI)2,275 enrolled3 locationsNCT00078078
Recruiting
Not Applicable

Effects of Amylopectin Chromium Blend on Whole-Body Protein Kinetics and Glucose in Peri/Post-Menopausal Women

Post-menopauseGlucose Monitoring, ContinuousWhole Body Protein Metabolism+1 more
Nutrition 21, Inc.60 enrolled1 locationNCT07402382
Recruiting
Not Applicable

Effects of Food Intake Sequence on Substrate Utilisation and Endurance Performance

Healthy ParticipantsSubstrate MetabolismEndurance Exercise
Universidade do Porto19 enrolled1 locationNCT07503990
Recruiting
Not Applicable

Effects of Ketone Ester Consumption on Exercise Tolerance and Cardiac Function

Type 2 DiabetesKetone Body MetabolismKetones, Metabolism
Ohio State University30 enrolled1 locationNCT06078683
Recruiting
Not Applicable

The Effects of Daytime, Nighttime, and Combined Heat Exposure on Human Health

Metabolism ChangesCardiovascular SystemPsychology Functional Behavior+1 more
Jian Cheng35 enrolled1 locationNCT07501923
Recruiting
Not Applicable

Multicomponent Intervention Study- Blood Donors With High Cholesterol

Lipid Metabolism Disorder
University of Texas Southwestern Medical Center100 enrolled1 locationNCT05693701
Recruiting

Menstrual Cycle Mapping While Using Closed-Loop Insulin Delivery

Diabetes Mellitus, Type 1Energy Metabolism
Lia Bally40 enrolled1 locationNCT07478211
Recruiting

Imaging Oxidative Metabolism and Neurotransmitter Synthesis in the Human Brain

Brain Metabolism
University of Texas Southwestern Medical Center28 enrolled1 locationNCT03849963
Recruiting

Retrospective Monocentric Evaluation of Biomarkers Associated With Bone, Muscle and Energy Metabolism

Energy MetabolismBone Remodeling
IRCCS San Raffaele1,000 enrolled1 locationNCT07454252
Recruiting
Not Applicable

The Effect of Hydration Status on Substrate Oxidation at Rest and During Light and Moderate Exercise

Hydration StatusSubstrate Metabolism During Exercise
PepsiCo Global R&D74 enrolled1 locationNCT07298863
Recruiting
Phase 1Phase 2

A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus

Metabolic DiseaseDiabetes Mellitus, Type 1Type 1 Diabetes+14 more
Otsuka Pharmaceutical Factory, Inc.13 enrolled1 locationNCT06575426
Recruiting
Phase 4

Observing Metabolism of EPA With Consideration of Genetics And Sex

HealthyOmega 3Metabolism, Lipids
University of Toronto64 enrolled1 locationNCT06975241
Recruiting
Early Phase 1

Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC

LeukemiaInborn Errors of MetabolismBone Marrow Failure Syndromes+2 more
Children's Hospital of Philadelphia100 enrolled1 locationNCT02356653
Recruiting
Not Applicable

Nighttime Synchrony of Your Nutrition and Circadian Health

SleepCircadian RhythmLifestyle Factors+5 more
University of Utah120 enrolled1 locationNCT07329283