Metabolism Clinical Trials

137 recruitingLast updated: June 18, 2026

There are 137 actively recruiting metabolism clinical trials across 31 countries. Studies span Not Applicable, Phase 2, Phase 4, Early Phase 1, Phase 1, Phase 3. Top locations include New York, New York, United States, Philadelphia, Pennsylvania, United States, Toronto, Ontario, Canada. Updated daily from ClinicalTrials.gov.


Metabolism Trials at a Glance

137 actively recruiting trials for metabolism are listed on ClinicalTrialsFinder across 6 cities in 31 countries. The largest study group is Not Applicable with 76 trials, with the heaviest enrollment activity in New York, Philadelphia, and Toronto. Lead sponsors running metabolism studies include Texas A&M University, Colorado State University, and Maastricht University Medical Center.

Browse metabolism trials by phase

Treatments under study

About Metabolism Clinical Trials

Looking for clinical trials for Metabolism? There are currently 20 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Metabolism trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Metabolism clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 137 trials

Recruiting

Clinical and Laboratory Study of Methylmalonic Acidemia

Inborn Errors of MetabolismOrganic AcidemiaMethylmalonic Acidemia
National Human Genome Research Institute (NHGRI)2,275 enrolled3 locationsNCT00078078
Recruiting

Impact of Shift Work on Glucose and Lipid Metabolism of Hospital Workers

Shift-work DisorderChronodisruptionGlucose and Lipid Metabolism
Olga Ramich (formerly Pivovarova)48 enrolled2 locationsNCT07426211
Recruiting

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

Hodgkin LymphomaNon-Hodgkin LymphomaHematologic Malignancies+14 more
Center for International Blood and Marrow Transplant Research99,999 enrolled142 locationsNCT01351545
Recruiting
Not Applicable

Exploration of Potential Biomarkers of Polyphenol Intake From Artichoke By-product Supplements

healthy adult participantsADMEPolyphenols Absorption Profile+1 more
Iziar Amaia Ludwig Sanz Orrio16 enrolled1 locationNCT07615673
Recruiting

Changes in Resting Metabolic Rate Following Orthopedic Surgery

Resting Metabolic RateMetabolism; Disorder, PostproceduralPost Operative Nutrition
University of Kansas Medical Center100 enrolled1 locationNCT06107959
Recruiting

Brain Metabolism Observed at 3 Tesla or 7 Tesla in Health and Metabolic Disease

EpilepsyGlucose Metabolism DisordersGlut1 Deficiency Syndrome 1+4 more
Weill Medical College of Cornell University20 enrolled2 locationsNCT05085704
Recruiting
Not Applicable

Energy Cost and Metabolic Intensity of Pilates Exercises in Older Adults

ExerciseAgingEnergy Metabolism
Universidade Estadual do Norte do Parana20 enrolled1 locationNCT07621523
Recruiting

Glucose-Level During Endurance Exercise

Glucose metabolism
University of Ulm100 enrolled1 locationNCT07543705
Recruiting
Not Applicable

Effect of Dairy Protein Yogourt vs Plant-based Yogourt on Body Weight, Body Composition, Bone Health and Gut Microbiota

bone metabolismMetabolic HealthGut Microbiota+3 more
Laval University75 enrolled1 locationNCT07578103
Recruiting
Not Applicable

Animal and Plant Proteins and Glucose Metabolism

Metabolic SyndromeGlucose Metabolism DisordersMetabolic Syndrome, Protection Against
University of Missouri-Columbia100 enrolled1 locationNCT03994367
Recruiting
Not Applicable

Stable Isotopes- Adults With Obesity

Protein metabolismGlucose metabolismObese Patients (BMI ≥ 30 kg/m²)
University of Illinois at Urbana-Champaign8 enrolled1 locationNCT07020741
Recruiting
Not Applicable

Diet Synergy in Muscle Protein Synthesis

Protein metabolismMuscle Protein SynthesisMuscle Health+3 more
University of Illinois at Urbana-Champaign15 enrolled2 locationsNCT07367854
Recruiting

Validating a New Machine-Learned Accelerometer Algorithm Using Doubly Labeled Water

Movement DisordersEnergy Metabolism
University of Wisconsin, Milwaukee125 enrolled1 locationNCT05736302
Recruiting
Phase 2

Regulation of Endogenous Glucose Production by Central KATP Channels

Diabetes MellitusGlucose Metabolism Disorders
Albert Einstein College of Medicine100 enrolled1 locationNCT03540758
Recruiting
Not Applicable

Amino Acid Metabolism in Fed Surgical Critically Ill Patients

Metabolism and Nutrition Disorder
Rabin Medical Center30 enrolled1 locationNCT03451968
Recruiting
Not Applicable

Amino Acid Oxidation of Whole-Food Protein: a Dose-Response Crossover Trial in Young Adults

Protein metabolism
Maastricht University Medical Center20 enrolled1 locationNCT07547176
Recruiting
Not Applicable

Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes

Insulin ResistanceHyperinsulinismDepression+5 more
Colorado State University300 enrolled2 locationsNCT05543083
Recruiting
Not Applicable

Effect of Ilex Paraguariensis Harvest Time and Consumption Method of Processed Yerba Mate on the Lipid Profile

Lipid Metabolism Disorders
Universidad Nacional de Caaguazu198 enrolled1 locationNCT06896175
Recruiting
Phase 3

A Phase 3 Study of NTLA-2001 in ATTRv-PN

Nervous system diseasePeripheral nervous system diseaseAmyloidosis+17 more
Intellia Therapeutics60 enrolled14 locationsNCT06672237
Recruiting
Phase 1Phase 2

Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

LeukemiaInborn Errors of MetabolismHLH+11 more
Children's Hospital of Philadelphia100 enrolled1 locationNCT06839456