Phase 1 Metastatic Pancreatic Cancer Clinical Trials
13 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–13 of 13 trials
Recruiting
Phase 1
Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors
Advanced Breast CancerAdvanced Solid TumorsMetastatic Pancreatic Cancer+3 more
National Cancer Institute (NCI)116 enrolled2 locationsNCT04222413
Recruiting
Phase 1Phase 2
Basal-like PDAC Treated With Gemcitabine, Erlotinib, and Nab-paclitaxel
Metastatic Pancreatic CancerPancreatic AdenocarcinomaBasal Cell Neoplasm
UNC Lineberger Comprehensive Cancer Center104 enrolled1 locationNCT06483555
Recruiting
Phase 1
A Phase 1 First-In-Human Study of the Anti-CD73 IPH5301 Alone or in Combination With Chemotherapy and Trastuzumab in Patients With Advanced Solid Tumors
Metastatic Breast CancerEndometrial CancerAdvanced Solid Tumor+6 more
Institut Paoli-Calmettes27 enrolled1 locationNCT05143970
Recruiting
Phase 1Phase 2
Nab-Paclitaxel + Cisplatin + Gemcitabine + TTF in pt. w/ Metastatic PAC
Metastatic Pancreatic CancerPancreas CancerPancreatic Adenocarcinoma+1 more
Mayo Clinic40 enrolled1 locationNCT04605913
Recruiting
Phase 1
SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells
Breast Cancer MetastaticPancreatic CancerHER2-negative Breast Cancer+9 more
General Oncology, Inc.24 enrolled2 locationsNCT04150042
Recruiting
Phase 1Phase 2
HRS-4642 Combination With Other Antitumor Therapies in Patients With Solid Tumors
Locally Advanced or Metastatic Pancreatic Cancer With
Shanghai Hengrui Pharmaceutical Co., Ltd.60 enrolled1 locationNCT07296341
Recruiting
Phase 1
A Phase 1 Trial of ERX-315 in Participants With Advanced Solid Tumors
Metastatic Breast CancerAdvanced Solid TumorMetastatic Ovarian Cancer+3 more
EtiraRx Australia Pty Ltd15 enrolled4 locationsNCT06533332
Recruiting
Phase 1Phase 2
Evaluation of Safety and Efficacy in BEY1107 in Monotherapy Gemcitabine Combination in Patient with Pancreatic Cancer
Locally Advanced or Metastatic Pancreatic Cancer
BeyondBio Inc.75 enrolled1 locationNCT03579836
Recruiting
Phase 1Phase 2
Combining Anti-PD-L1 Immune Checkpoint Inhibitor Durvalumab With TLR-3 Agonist Rintatolimod in Patients With Metastatic Pancreatic Ductal Adenocarcinoma for Therapy Efficacy
Metastatic Pancreatic Cancer
Joachim Aerts, MD PhD43 enrolled1 locationNCT05927142
Recruiting
Phase 1Phase 2
A Study of Evofosfamide in Combination with Zalifrelimab and Balstilimab
Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Pancreatic CancerMetastatic Prostate Cancer
ImmunoGenesis71 enrolled1 locationNCT06782555
Recruiting
Phase 1Phase 2
mFOLFIRINOX Plus Anlotinib and Sintilimab for Advanced Pancreatic Cancer
Metastatic Pancreatic CancerLocally Advanced Pancreatic Cancer
Fujian Provincial Hospital29 enrolled4 locationsNCT06761027
Recruiting
Phase 1Phase 2
Phase Ib/II Clinical Study of Adebrelimab in Combination With Decitabine, Albumin-bound Paclitaxel, and Gemcitabine for the First-line Treatment of Metastatic Pancreatic Cancer
Metastatic Pancreatic CancerAdebrelimab (SHR-1316)Decitabine
Tianjin Medical University Cancer Institute and Hospital20 enrolled1 locationNCT06454448
Recruiting
Phase 1Phase 2
Study of Effect of Azeliragon in Patients Refractory to Prior Treatment of Metastatic Pancreatic Cancer
Metastatic Pancreatic Cancer
Cantex Pharmaceuticals30 enrolled6 locationsNCT05766748